The geometric model of the human mitral valve

The mitral valve, which lies between the left atrium and the left ventricle, plays an important role in controlling the uniflux of blood from the left atrium to the left ventricle as one of the four human heart valves. A precise description of the shape of human mitral valve has vital significance in studying its physiological structure and periodic movement. Unsatisfyingly, there is almost no unified mathematical description of the same shape of human mitral valve in literature. In this paper, we present a geometric model for human mitral valve, as an elastic shell with a special shape. Parametric equations for the shape of human mitral valve are provided, including the anterior and the posterior parts, which can be thought as portions of two interfacing semi-elliptic cylindrical shells. The minor axis of one ellipse is equal to the major axis of the other. All the parameters are determined from the statistical data. Comparison of fitting results with existing examples validates the accuracy of our geometric model. Based on the fitting shape, one can further simulate the physiological function of the mitral valve using a suitable dynamic physical equation.

[1]  Boyce E. Griffith,et al.  Image-based fluid-structure interaction model of the human mitral valve , 2013 .

[2]  Alberto Redaelli,et al.  Mitral valve finite element modeling: implications of tissues' nonlinear response and annular motion. , 2009, Journal of biomechanical engineering.

[3]  A. Yoganathan,et al.  Heart valve function: a biomechanical perspective , 2008, Philosophical Transactions of the Royal Society B: Biological Sciences.

[4]  Daoqiang Zhang,et al.  View‐centralized multi‐atlas classification for Alzheimer's disease diagnosis , 2015, Human brain mapping.

[5]  Robert D. Howe,et al.  Patient-Specific Mitral Leaflet Segmentation from 4D Ultrasound , 2011, MICCAI.

[6]  David Liang,et al.  Aorto-mitral annular dynamics. , 2003, The Annals of thoracic surgery.

[7]  J. Edwards,et al.  Studies of the Mitral Valve. I. Anatomic Features of the Normal Mitral Valve and Associated Structures , 1952, Circulation.

[8]  R. Schneider Semi-Automatic Delineation of the Mitral Valve from Clinical Four-Dimensional Ultrasound Imaging , 2011 .

[9]  Colin Berry,et al.  Modelling mitral valvular dynamics–current trend and future directions , 2017, International journal for numerical methods in biomedical engineering.

[10]  Gunnar Seemann,et al.  Functional Imaging and Modeling of the Heart , 2003, Lecture Notes in Computer Science.

[11]  P Dagum,et al.  Three-dimensional geometric comparison of partial and complete flexible mitral annuloplasty rings. , 2001, Journal of Thoracic and Cardiovascular Surgery.

[12]  W. S. Ring,et al.  Finite element analysis of the mitral valve. , 1993, The Journal of heart valve disease.

[13]  E D Wigle,et al.  Morphology of the Human Mitral Valve: II. The Valve Leaflets , 1970, Circulation.

[14]  Eli J Weinberg,et al.  A finite shell element for heart mitral valve leaflet mechanics, with large deformations and 3D constitutive material model. , 2007, Journal of biomechanics.

[15]  M. A. Chiechi,et al.  Functional anatomy of the normal mitral valve. , 1956, The Journal of thoracic surgery.

[16]  K S Kunzelman,et al.  Anatomic basis for mitral valve modelling. , 1994, The Journal of heart valve disease.

[17]  Robert D. Howe,et al.  Modeling Mitral Valve Leaflets from Three-Dimensional Ultrasound , 2011, FIMH.

[18]  J. Dominik,et al.  Heart valve surgery , 2010 .

[19]  Daoqiang Zhang,et al.  Relationship Induced Multi-Template Learning for Diagnosis of Alzheimer’s Disease and Mild Cognitive Impairment , 2016, IEEE Transactions on Medical Imaging.