Detection of protein-protein interactions in vivo based on protein splicing.

[1]  Y. Umezawa,et al.  Split luciferase as an optical probe for detecting protein-protein interactions in mammalian cells based on protein splicing. , 2001, Analytical chemistry.

[2]  D. Ladant,et al.  Genetic systems for analyzing protein-protein interactions in bacteria. , 2000, Research in microbiology.

[3]  A. Aronheim.  Protein recruitment systems for the analysis of protein-protein interactions. , 2000, Biochemical pharmacology.

[4]  Y. Ohya,et al.  A fluorescent indicator for detecting protein-protein interactions in vivo based on protein splicing. , 2000, Analytical chemistry.

[5]  K. Isselbacher,et al.  A green fluorescent protein-reporter mammalian two-hybrid system with extrachromosomal maintenance of a prey expression plasmid: application to interaction screening. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[6]  T. C. Evans,et al.  Protein trans-Splicing and Cyclization by a Naturally Split Intein from the dnaE Gene ofSynechocystis Species PCC6803* , 2000, The Journal of Biological Chemistry.

[7]  Noren,et al.  Dissecting the Chemistry of Protein Splicing and Its Applications. , 2000, Angewandte Chemie.

[8]  Michelle Palmer,et al.  Epidermal growth factor receptor dimerization monitored in live cells , 2000, Nature Biotechnology.

[9]  S. Benkovic,et al.  Production of cyclic peptides and proteins in vivo. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[10]  Y. Kyōgoku,et al.  NMR observation of selected segments in a larger protein: central-segment isotope labeling through intein-mediated ligation. , 1999, Biochemistry.

[11]  Andreas Plückthun,et al.  Circular β‐lactamase: stability enhancement by cyclizing the backbone , 1999 .

[12]  T. C. Evans,et al.  The Cyclization and Polymerization of Bacterially Expressed Proteins Using Modified Self-splicing Inteins* , 1999, The Journal of Biological Chemistry.

[13]  T. Muir,et al.  Biosynthesis of a Head-to-Tail Cyclized Protein with Improved Biological Activity , 1999 .

[14]  S. Michnick,et al.  Clonal selection and in vivo quantitation of protein interactions with protein-fragment complementation assays. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[15]  R G Smith,et al.  Discovery of a small molecule insulin mimetic with antidiabetic activity in mice. , 1999, Science.

[16]  I. Wilson,et al.  Erythropoietin receptor activation by a ligand-induced conformation change. , 1999, Science.

[17]  T. Muir,et al.  Insertion of a Synthetic Peptide into a Recombinant Protein Framework: A Protein Biosensor , 1999 .

[18]  D Cowburn,et al.  Chemical ligation of folded recombinant proteins: segmental isotopic labeling of domains for NMR studies. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[19]  A. Aronheim,et al.  The Ras recruitment system, a novel approach to the study of protein–protein interactions , 1998, Current Biology.

[20]  Z. Hu,et al.  Protein trans-splicing by a split intein encoded in a split DnaE gene of Synechocystis sp. PCC6803. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[21]  T. Muir,et al.  Expressed Protein Ligation, a Novel Method for Studying Protein-Protein Interactions in Transcription* , 1998, The Journal of Biological Chemistry.

[22]  T. Muir,et al.  Expressed protein ligation: a general method for protein engineering. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[23]  D. Ladant,et al.  A bacterial two-hybrid system based on a reconstituted signal transduction pathway. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[24]  I. Stagljar,et al.  A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[25]  H. Blau,et al.  Monitoring protein-protein interactions in intact eukaryotic cells by beta-galactosidase complementation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[26]  A. Aronheim,et al.  Improved efficiency sos recruitment system: expression of the mammalian GAP reduces isolation of Ras GTPase false positives. , 1997, Nucleic acids research.

[27]  F. Perler,et al.  Single-column purification of free recombinant proteins using a self-cleavable affinity tag derived from a protein splicing element. , 1997, Gene.

[28]  S. Elledge,et al.  Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions , 1997, Molecular and cellular biology.

[29]  Roger Y. Tsien,et al.  Crystal Structure of the Aequorea victoria Green Fluorescent Protein , 1996, Science.

[30]  P. Brick,et al.  Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes. , 1996, Structure.

[31]  A. Varshavsky,et al.  Split ubiquitin as a sensor of protein interactions in vivo. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[32]  S. Fields,et al.  The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[33]  P. Kane,et al.  Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar H(+)-adenosine triphosphatase. , 1990, Science.

[34]  R. Hirata,et al.  Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. , 1990, The Journal of biological chemistry.

[35]  S. Fields,et al.  A novel genetic system to detect protein–protein interactions , 1989, Nature.

[36]  H. Paulus,et al.  Protein splicing and related forms of protein autoprocessing. , 2000, Annual review of biochemistry.

[37]  C. Chien.  A novel genetic system to detect protein-protein interactions , 1991 .