Patterns of Comorbidity in Older Adults with Heart Failure: The Cardiovascular Research Network PRESERVE Study

To examine whether the total burden of comorbidity and pattern of co‐occurring conditions varies in individuals with heart failure (HF) with preserved left ventricular ejection fraction (LVEF) (HF‐P) or HF with reduced LVEF (HF‐R).

[1]  Charles E McCulloch,et al.  Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. , 2004, The New England journal of medicine.

[2]  A. Go,et al.  Hemoglobin Level, Chronic Kidney Disease, and the Risks of Death and Hospitalization in Adults With Chronic Heart Failure: The Anemia in Chronic Heart Failure: Outcomes and Resource Utilization (ANCHOR) Study , 2006, Circulation.

[3]  Longjian Liu Changes in cardiovascular hospitalization and comorbidity of heart failure in the United States: findings from the National Hospital Discharge Surveys 1980-2006. , 2011, International journal of cardiology.

[4]  J. Cromwell,et al.  Results of the Medicare Health Support disease-management pilot program. , 2011, The New England journal of medicine.

[5]  E. D. de Kemp,et al.  Dementia and depression symptomatology as assessed through screening tests of older patients in an outpatient clinic. , 1994, Family practice research journal.

[6]  A. Go,et al.  Comparative effectiveness of different beta-adrenergic antagonists on mortality among adults with heart failure in clinical practice. , 2008, Archives of internal medicine.

[7]  B. Winblad,et al.  Patterns of Chronic Multimorbidity in the Elderly Population , 2009, Journal of the American Geriatrics Society.

[8]  Terri R. Fried,et al.  Change in Comorbidity Prevalence with Advancing Age Among Persons with Heart Failure , 2011, Journal of General Internal Medicine.

[9]  Sangeeta C. Ahluwalia,et al.  Impact of Comorbidity on Mortality Among Older Persons with Advanced Heart Failure , 2012, Journal of General Internal Medicine.

[10]  R. Deyo,et al.  Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. , 1992, Journal of clinical epidemiology.

[11]  A. Nobili,et al.  Adverse drug reactions caused by drug–drug interactions in elderly outpatients: a prospective cohort study , 2012, European Journal of Clinical Pharmacology.

[12]  William D. Marder,et al.  Multiple Chronic Conditions: Prevalence, Health Consequences, and Implications for Quality, Care Management, and Costs , 2007, Journal of General Internal Medicine.

[13]  H. Cohen,et al.  Report of the national institute on aging task force on comorbidity. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

[14]  Cynthia M Boyd,et al.  From Bedside to Bench: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Comorbidity and Multiple Morbidity in Older Adults , 2008, Aging clinical and experimental research.

[15]  Bruce Leff,et al.  Informing Clinical Practice Guideline Development and Implementation: Prevalence of Coexisting Conditions Among Adults with Coronary Heart Disease , 2011, Journal of the American Geriatrics Society.

[16]  Albert W Wu,et al.  Noncardiac comorbidity increases preventable hospitalizations and mortality among Medicare beneficiaries with chronic heart failure. , 2003, Journal of the American College of Cardiology.

[17]  Harlan M Krumholz,et al.  Trends in comorbidity, disability, and polypharmacy in heart failure. , 2011, The American journal of medicine.

[18]  C. Lang,et al.  Non-cardiac comorbidities in chronic heart failure , 2006, Heart.

[19]  Peter C Austin,et al.  Outcome of heart failure with preserved ejection fraction in a population-based study. , 2006, The New England journal of medicine.

[20]  C. Büla,et al.  Cognitive impairment in elderly medical inpatients: detection and associated six-month outcomes. , 2004, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[21]  B. Starfield,et al.  Prevalence, expenditures, and complications of multiple chronic conditions in the elderly. , 2002, Archives of internal medicine.

[22]  Robert N. Doughty,et al.  The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: an individual patient data meta-analysis. , 2011, European heart journal.

[23]  H. Krumholz,et al.  Polypharmacy and comorbidity in heart failure , 2003, BMJ : British Medical Journal.

[24]  A. Parekh,et al.  The challenge of multiple comorbidity for the US health care system. , 2010, JAMA.

[25]  V. Roger,et al.  Trends in prevalence and outcome of heart failure with preserved ejection fraction. , 2006, The New England journal of medicine.

[26]  A. Wu,et al.  Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. , 2005, JAMA.

[27]  A. Go,et al.  Statin therapy and risks for death and hospitalization in chronic heart failure. , 2006, JAMA.

[28]  W. Kannel,et al.  The natural history of congestive heart failure: the Framingham study. , 1971, The New England journal of medicine.

[29]  Jerry H Gurwitz,et al.  Creating a research data network for cardiovascular disease: the CVRN , 2008, Expert review of cardiovascular therapy.

[30]  B. Greenberg,et al.  Transforming health care through the medical home: the example of heart failure. , 2009, Journal of cardiac failure.

[31]  D. Blumenthal,et al.  Mortality Rate in Veterans with Multiple Chronic Conditions , 2007, Journal of General Internal Medicine.

[32]  Laura Fratiglioni,et al.  Prevalence of chronic diseases and multimorbidity among the elderly population in Sweden. , 2008, American journal of public health.