Vitamin D deficiency as a risk factor for infection, sepsis and mortality in the critically ill: systematic review and meta-analysis

[1]  C. Camargo,et al.  Prospective Study of Vitamin D Status at Initiation of Care in Critically Ill Surgical Patients and Risk of 90-Day Mortality* , 2014, Critical care medicine.

[2]  T. Pieber,et al.  Vitamin D status and its association with season, hospital and sepsis mortality in critical illness , 2014, Critical Care.

[3]  E. Giovannucci,et al.  Association of Low Serum 25-Hydroxyvitamin D Levels and Sepsis in the Critically Ill , 2014, Critical care medicine.

[4]  P. Autier,et al.  Vitamin D status and ill health: a systematic review. , 2014, The lancet. Diabetes & endocrinology.

[5]  G. Aygencel,et al.  Is Vitamin D Insufficiency Associated with Mortality of Critically Ill Patients? , 2013, Critical care research and practice.

[6]  L. Su,et al.  Significance of low serum vitamin D for infection risk, disease severity and mortality in critically ill patients. , 2013, Chinese medical journal.

[7]  Russell R. Miller,et al.  Vitamin D and delirium in critically ill patients: a preliminary investigation. , 2013, Journal of critical care.

[8]  P. Pickkers,et al.  Vitamin D status is not associated with inflammatory cytokine levels during experimental human endotoxaemia , 2013, Clinical and experimental immunology.

[9]  J. Eisman,et al.  Significant perturbation of vitamin D–parathyroid–calcium axis and adverse clinical outcomes in critically ill patients , 2013, Intensive Care Medicine.

[10]  W. Bos,et al.  Addition of vitamin D status to prognostic scores improves the prediction of outcome in community-acquired pneumonia. , 2012, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[11]  Y. Ahmed,et al.  Worsening severity of vitamin D deficiency is associated with increased length of stay, surgical intensive care unit cost, and mortality rate in surgical intensive care unit patients. , 2012, American journal of surgery.

[12]  H. Amital,et al.  Vitamin D deficiency is associated with poor outcomes and increased mortality in severely ill patients. , 2012, QJM : monthly journal of the Association of Physicians.

[13]  J. Christensen,et al.  A reverse J-shaped association of all-cause mortality with serum 25-hydroxyvitamin D in general practice: the CopD study. , 2012, The Journal of clinical endocrinology and metabolism.

[14]  D. Heyland,et al.  Relationship of vitamin D deficiency to clinical outcomes in critically ill patients. , 2012, JPEN. Journal of parenteral and enteral nutrition.

[15]  C. Gordon,et al.  Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited. , 2012, The Journal of clinical endocrinology and metabolism.

[16]  E. Giovannucci,et al.  Low serum 25-hydroxyvitamin D levels and acute kidney injury in the critically ill , 2012, Critical Care.

[17]  R. Wilson,et al.  Effects of vitamin D deficiency in critically ill surgical patients. , 2012, American journal of surgery.

[18]  E. Giovannucci,et al.  Low serum 25-hydroxyvitamin D at critical care initiation is associated with increased mortality* , 2012, Critical care medicine.

[19]  S. Chilimuri,et al.  Vitamin D deficiency is associated with mortality in the medical intensive care unit , 2011, Critical care.

[20]  Paul Lee.  Vitamin D metabolism and deficiency in critical illness. , 2011, Best practice & research. Clinical endocrinology & metabolism.

[21]  Michelino Di Rosa,et al.  Vitamin D3: a helpful immuno‐modulator , 2011, Immunology.

[22]  G. Zagli,et al.  Vitamin D deficiency in septic patients at ICU admission is not a mortality predictor. , 2011, Minerva anestesiologica.

[23]  J. M. Mata-Granados,et al.  PP150-T25-hydroxyvitamin D3 treatment normalize the vitamin D status and the innate immune response mediated by cathelicidin in critically ill patients , 2011 .

[24]  E. Giovannucci,et al.  Association of low serum 25-hydroxyvitamin D levels and mortality in the critically ill* , 2011, Critical care medicine.

[25]  T. Pieber,et al.  Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study , 2011, Critical care.

[26]  B. Bailey,et al.  Relationship between vitamin D status and ICU outcomes in veterans. , 2011, Journal of the American Medical Directors Association.

[27]  JoAnn E. Manson,et al.  The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know , 2010, The Journal of clinical endocrinology and metabolism.

[28]  M. Netea,et al.  1,25-dihydroxyvitamin D3 modulates cytokine production induced by Candida albicans: impact of seasonal variation of immune responses. , 2011, The Journal of infectious diseases.

[29]  Mark Jones,et al.  Do random estimations of vitamin D3 and parathyroid hormone reflect the 24-h profile in the critically ill? , 2011, Intensive Care Medicine.

[30]  J. M. Mata-Granados,et al.  Evaluation of vitamin D endocrine system (VDES) status and response to treatment of patients in intensive care units (ICUs) using an on-line SPE-LC-MS/MS method , 2010, Journal of Steroid Biochemistry and Molecular Biology.

[31]  O. Lucidarme,et al.  Incidence and risk factors of vitamin D deficiency in critically ill patients: results from a prospective observational study , 2010, Intensive Care Medicine.

[32]  H. O. Oudemans-van Straaten,et al.  High prevalence of severe vitamin D deficiency in intensive care patients , 2010, Critical Care.

[33]  J. Eisman,et al.  Vitamin D deficiency in the intensive care unit: an invisible accomplice to morbidity and mortality? , 2009, Intensive Care Medicine.

[34]  G. Tenderich,et al.  Circulating calcitriol concentrations and total mortality. , 2009, Clinical chemistry.

[35]  G. Martin,et al.  Journal of Translational Medicine BioMed Central Review , 2008 .

[36]  H. Weber,et al.  Accuracy and clinical implications of seven 25-hydroxyvitamin D methods compared with liquid chromatography–tandem mass spectrometry as a reference , 2008, Annals of clinical biochemistry.

[37]  T. Marshall.  Vitamin D discovery outpaces FDA decision making , 2008, BioEssays : news and reviews in molecular, cellular and developmental biology.

[38]  Sara Gandini,et al.  Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. , 2007, Archives of internal medicine.

[39]  W. Willett,et al.  The urgent need to recommend an intake of vitamin D that is effective. , 2007, The American journal of clinical nutrition.

[40]  J. Adams,et al.  Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response , 2006, Science.

[41]  D. Zehnder,et al.  Vitamin D and barrier function: a novel role for extra-renal 1α-hydroxylase , 2004, Molecular and Cellular Endocrinology.

[42]  D. Zehnder,et al.  Vitamin D and barrier function: a novel role for extra-renal 1 alpha-hydroxylase. , 2004, Molecular and cellular endocrinology.

[43]  G. Van den Berghe,et al.  Bone turnover in prolonged critical illness: effect of vitamin D , 2003, The Journal of clinical endocrinology and metabolism.

[44]  I. Olkin,et al.  Meta-analysis of observational studies in epidemiology - A proposal for reporting , 2000 .

[45]  B. Chernow,et al.  Hypocalcemia in critical illness. , 1986, JAMA.