Transcriptional Activators of TGF-β Responses: Smads

[1]  H. Lodish,et al.  Synergistic cooperation of TFE3 and smad proteins in TGF-beta-induced transcription of the plasminogen activator inhibitor-1 gene. , 1998, Genes & development.

[2]  Yigong Shi,et al.  Crystal Structure of a Smad MH1 Domain Bound to DNA Insights on DNA Binding in TGF-β Signaling , 1998, Cell.

[3]  J. Massagué,et al.  Physical and Functional Interaction of SMADs and p300/CBP* , 1998, The Journal of Biological Chemistry.

[4]  R. Derynck,et al.  Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β-induced transcription , 1998, Nature.

[5]  K. Isselbacher,et al.  Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[6]  M. Whitman.  Smads and early developmental signaling by the TGFbeta superfamily. , 1998, Genes & development.

[7]  C. Heldin,et al.  Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer* , 1998, The Journal of Biological Chemistry.

[8]  J. D. Brown,et al.  CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[9]  M. Frasch,et al.  Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. , 1998, Genes & development.

[10]  R. Derynck,et al.  The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation. , 1998, Genes & development.

[11]  J. Massagué,et al.  Determinants of specificity in TGF-beta signal transduction. , 1998, Genes & development.

[12]  T. Hunter,et al.  TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300. , 1998, Genes & development.

[13]  M. Bienz,et al.  Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm induction. , 1998, Genes & development.

[14]  P. Hoodless,et al.  Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2. , 1998, Molecular cell.

[15]  K. Kinzler,et al.  Characterization of human FAST-1, a TGFβ and activin signal transducer , 1998 .

[16]  A. Moustakas,et al.  Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[17]  Denis Vivien,et al.  Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene , 1998, The EMBO journal.

[18]  Kohei Miyazono,et al.  TGF-β signalling from cell membrane to nucleus through SMAD proteins , 1997, Nature.

[19]  J. Massagué,et al.  Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes. , 1997, Genes & development.

[20]  Xiao-Fan Wang,et al.  Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein , 1997, Molecular and cellular biology.

[21]  J. Darnell.  STATs and gene regulation. , 1997, Science.

[22]  Minoru Watanabe,et al.  Smad4 and FAST-1 in the assembly of activin-responsive factor , 1997, Nature.

[23]  Kirby D. Johnson,et al.  Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic , 1997, Nature.

[24]  J. Massagué,et al.  Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4 , 1997, Nature.

[25]  Xin Chen,et al.  A transcriptional partner for MAD proteins in TGF-β signalling , 1996, Nature.

[26]  Xiao-Fan Wang,et al.  Functional Analysis of the Transforming Growth Factor βResponsive Elements in the WAF1/Cip1/p21 Promoter (*) , 1995, The Journal of Biological Chemistry.

[27]  M. Goebl,et al.  A chimeric ubiquitin conjugating enzyme that combines the cell cycle properties of CDC34 (UBC3) and the DNA repair properties of RAD6 (UBC2): implications for the structure, function and evolution of the E2s. , 1992, The EMBO journal.

[28]  J. Massagué.  TGF-beta signal transduction. , 1998, Annual review of biochemistry.