Glimepiride and Serum Adiponectin Level in Type 2 Diabetic Subjects: Response to Yoshioka, Yoshida, and Yoshikawa

We thank Yoshioka, Yoshida, and Yoshikawa for their comments on our article (1) in this issue of Diabetes Care (2). We reported that serum adiponectin concentration increased after 3 months’ glimepiride treatment in type 2 diabetic patients (1). They indicated that baseline values of serum adiponectin (22.1 ± 2.7 μg/ml, mean ± SE) seem to be higher than those expected from subjects with greater BMI (26.5 ± 0.9 kg/m2) and homeostasis model assessment of insulin resistance (5.0 ± 0.8) levels. First, we must apologize …