ONTOGÊNESE DO SISTEMA DE TEMPORIZAÇÃO - A CONSTRUÇÃO E AS REFORMAS DOS RITMOS BIOLÓGICOS AO LONGO DA VIDA HUMANA

Nesta revisao apresentamos fatos e comentarios sobre a evolucao dos sistemas de temporizacao ("relogios biologicos") na especie humana. Na Introducao definimos alguns conceitos basicos da Cronobiologia que serao utilizados ao longo do artigo. Nas quatro secoes subsequentes, discutimos fatos marcantes que caracterizam a ritmicidade biologica em distintas etapas da ontogenese: bebes, adolescentes, adultos e idosos. Concluimos o artigo com um convite a reflexao sobre as perspectivas que se abrem com esse novo campo do conhecimento.

[1]  M. Härmä.  Ageing, physical fitness and shiftwork tolerance. , 1996, Applied ergonomics.

[2]  R. Kronauer,et al.  Stability, precision, and near-24-hour period of the human circadian pacemaker. , 1999, Science.

[3]  W. B. Webb.  Sleep, biological rhythms and aging. , 1978, Advances in experimental medicine and biology.

[4]  M. F. Ceolim,et al.  Sleep/wake cycle and physical activity in healthy elderly people. , 2000, Sleep research online : SRO.

[5]  F. Louzada,et al.  A Four-Year Follow-Up Study of the Sleep-Wake Cycle of an Infant , 1996 .

[6]  Drew Dawson,et al.  Daytime melatonin and temazepam in young adult humans: equivalent effects on sleep latency and body temperatures , 1999, The Journal of physiology.

[7]  S. Chinn,et al.  Sleep habits and height at ages 5 to 11. , 1990, Archives of disease in childhood.

[8]  Lúcia Rotenberg,et al.  Trabalho em turnos e noturno na sociedade 24 horas , 2003 .

[9]  A. Sadeh,et al.  Sleep patterns and sleep disruptions in school-age children. , 2000, Developmental psychology.

[10]  A. Bartke,et al.  Could a deficiency in growth hormone signaling be beneficial to the aging brain? , 2004, Physiology & Behavior.

[11]  P Valdez,et al.  Delaying and extending sleep during weekends: sleep recovery or circadian effect? , 1996, Chronobiology international.

[12]  M. Carskadon,et al.  Sleep fragmentation in the elderly: Relationship to daytime sleep tendency , 1982, Neurobiology of Aging.

[13]  Yuichi Inoue,et al.  Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome , 2001, EMBO reports.

[14]  Alan Fogel,et al.  Systems, Cycles, and Developmental Pathways , 1999, Human Development.

[15]  G. Klackenberg.  SLEEP BEHAVIOUR STUDIED LONGITUDINALLY , 1982, Acta paediatrica Scandinavica.

[16]  F. Louzada,et al.  Sleep-Wake Cycle Expression in Adolescence: Influences of Social Context , 2003 .

[17]  M. Carskadon,et al.  Association between puberty and delayed phase preference. , 1993, Sleep.

[18]  S. Reppert.  Pre-natal development of a hypothalamic biological clock. , 1992, Progress in brain research.

[19]  Patricia R. Houck,et al.  Circadian temperature rhythms of older people , 1995, Experimental Gerontology.

[20]  M. Brock.  Chronobiology and Aging , 1991, Journal of the American Geriatrics Society.

[21]  A. H. Parmelee,et al.  Sleep patterns of the newborn. , 1961, The Journal of pediatrics.

[22]  P. Zee,et al.  Effects of age on the circadian system , 1995, Neuroscience & Biobehavioral Reviews.

[23]  R. Moore,et al.  A retinohypothalamic projection in the rat , 1972, The Journal of comparative neurology.

[24]  K. Pettigrew,et al.  Motor activity and sleep duration as a function of age in healthy men , 1987, Physiology & Behavior.

[25]  M. Mirmiran,et al.  Aging and circadian rhythms. , 1986, Progress in brain research.

[26]  Claudio Stampi,et al.  Why we nap : evolution, chronobiology, and functions of polyphasic and ultrashort sleep , 1992 .

[27]  C A Czeisler,et al.  CONTRIBUTION OF CIRCADIAN PHYSIOLOGY AND SLEEP HOMEOSTASIS TO AGE-RELATED CHANGES IN HUMAN SLEEP , 2000, Chronobiology international.

[28]  N. Kleitman,et al.  Sleep characteristics of infants. , 1953, Journal of applied physiology.

[29]  A. Díez-Noguera,et al.  A functional model of the circadian system based on the degree of intercommunication in a complex system. , 1994, The American journal of physiology.

[30]  R. Dahl,et al.  Pathways to adolescent health sleep regulation and behavior. , 2002, The Journal of adolescent health : official publication of the Society for Adolescent Medicine.

[31]  D J Foley,et al.  Sleep complaints among elderly persons: an epidemiologic study of three communities. , 1995, Sleep.

[32]  F. Carandente,et al.  From the Glossary of chronobiology , 1984, La Ricerca in clinica e in laboratorio.

[33]  A. Healy.  The Sleep Patterns of Preschool Children , 1972, Clinical pediatrics.

[34]  J. Aschoff,et al.  Desynchronization of human circadian rhythms. , 1967, The Japanese journal of physiology.

[35]  L Menna-Barreto,et al.  Sleep characteristics of adolescents: a longitudinal study. , 1993, The Journal of adolescent health : official publication of the Society for Adolescent Medicine.

[36]  A. Wirz-Justice,et al.  Circadian Rhythm Mechanisms in Affective Illness and in Antidepressant Drug Action , 1982, Pharmacopsychiatria.

[37]  M. Sterman,et al.  Studies of maternal-fetal interaction during the last trimester of pregnancy: Ontogenesis of the basic rest-activity cycle , 1978, Experimental Neurology.

[38]  F. Louzada,et al.  A Longitudinal Study of the Sleep-Wake Cycle in Children Living on the Same School Schedules , 1996 .

[39]  R. Soussignan,et al.  The sleep/wake cycle in 4- to 14-month old children: general aspects and sex differences. , 1989, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

[40]  Y. Fuyama,et al.  Application of the gene search system to screen for longevity genes in Drosophila , 2004, Biogerontology.

[41]  R. Brandstaetter.  Circadian lessons from peripheral clocks: is the time of the mammalian pacemaker up? , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[42]  Samis Hv.  Aging: the loss of temporal organization. , 1968 .

[43]  R. Dahl,et al.  The impact of inadequate sleep on children's daytime cognitive function. , 1996, Seminars in pediatric neurology.

[44]  D. Swaab,et al.  Senescence, sleep, and circadian rhythms , 2002, Ageing Research Reviews.

[45]  M Weissbluth,et al.  Naps in children: 6 months-7 years. , 1995, Sleep.

[46]  M. Ralph,et al.  The Significance of Circadian Organization for Longevity in the Golden Hamster , 1998, Journal of biological rhythms.

[47]  R. Soussignan,et al.  New Data on the Wake‐Sleep Rhythm of Children Aged from 2 1/2 to 4 1/2 Years , 1984, Acta paediatrica Scandinavica.

[48]  E. van Cauter,et al.  Effects of ageing on modulation of hormonal secretions by sleep and circadian rhythmicity. , 1995, Hormone research.