The Endocrine Regulation of Aging by Insulin-like Signals
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[1] Donald L Riddle,et al. DAF-9, a cytochrome P450 regulating C. elegans larval development and adult longevity. , 2002, Development.
[2] C. Finch,et al. Genetics of aging. , 1997, Science.
[3] C. Kenyon,et al. A C. elegans mutant that lives twice as long as wild type , 1993, Nature.
[4] R. Nusse,et al. Ablation of Insulin-Producing Neurons in Flies: Growth and Diabetic Phenotypes , 2002, Science.
[5] C. Thummel,et al. Steroid Regulation of Postembryonic Development and Reproduction in Drosophila , 2000, Trends in Endocrinology & Metabolism.
[6] S. Tobe,et al. The Regulation of Juvenile Hormone Production in Arthropods: Functional and Evolutionary Perspectives , 1999, Annals of the New York Academy of Sciences.
[7] V. Rottiers,et al. A hormonal signaling pathway influencing C. elegans metabolism, reproductive development, and life span. , 2001, Developmental cell.
[8] A. Spradling,et al. Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis. , 2001, Developmental biology.
[9] Leo X. Liu,et al. Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family. , 2001, Genes & development.
[10] E. Hafen,et al. An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control , 2001, Current Biology.
[11] M. Riehle,et al. Insulin stimulates ecdysteroid production through a conserved signaling cascade in the mosquito Aedes aegypti. , 1999, Insect biochemistry and molecular biology.
[12] D. Ingram,et al. Biomarkers of Caloric Restriction May Predict Longevity in Humans , 2002, Science.
[13] D. Riddle,et al. Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans. , 1998, Genetics.
[14] Yong Xu,et al. Activation of transcription through the ligand-binding pocket of the orphan nuclear receptor ultraspiracle. , 2002, European journal of biochemistry.
[15] Nicholas K. Priest,et al. Negligible Senescence during Reproductive Dormancy in Drosophila melanogaster , 2001, The American Naturalist.
[16] M. Mckeown,et al. SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. , 1999, Molecular cell.
[17] M. Tatar,et al. A Mutant Drosophila Insulin Receptor Homolog That Extends Life-Span and Impairs Neuroendocrine Function , 2001, Science.
[18] M. Ravenel. Pulmonary Tuberculosis and Its Complications , 1909 .
[19] W. Sellers,et al. A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. , 2002, Cancer cell.
[20] Cynthia Kenyon,et al. Timing Requirements for Insulin/IGF-1 Signaling in C. elegans , 2002, Science.
[21] D. Rudman,et al. Effects of human growth hormone in men over 60 years old. , 1990, The New England journal of medicine.
[22] M. Tatar,et al. Impaired ovarian ecdysone synthesis of Drosophila melanogaster insulin receptor mutants , 2002, Aging cell.
[23] M. Arbeitman,et al. Molecular Chaperones Activate the Drosophila Ecdysone Receptor, an RXR Heterodimer , 2000, Cell.
[24] Andrzej Bartke,et al. Longevity: Extending the lifespan of long-lived mice , 2001, Nature.
[25] G. Fink,et al. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration , 2002, Nature.
[26] M. Romero,et al. Effect of thyroid hormones on mitochondrial oxygen free radical production and DNA oxidative damage in the rat heart , 2000, Molecular and Cellular Endocrinology.
[27] Chi-Yung Lai,et al. Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. , 1999, Molecular biology of the cell.
[28] D. Clemmons,et al. Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. , 2000, Endocrinology.
[29] R. Garofalo. Genetic analysis of insulin signaling in Drosophila , 2002, Trends in Endocrinology & Metabolism.
[30] J. Cline,et al. Growth hormone-deficient dwarf animals are resistant to dimethylbenzanthracine (DMBA)-induced mammary carcinogenesis. , 2002, Endocrinology.
[31] Katherine A. Kelley,et al. Comparative endocrinology of the insulin-like growth factor-binding protein. , 2002, The Journal of endocrinology.
[32] R. Evans,et al. Nuclear receptors and lipid physiology: opening the X-files. , 2001, Science.
[33] J L Wang,et al. Dual modes of aging in Mediterranean fruit fly females. , 1998, Science.
[34] C. Kahn,et al. Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. , 2002, Developmental cell.
[35] Martin Holzenberger,et al. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice , 2003, Nature.
[36] P. Holland,et al. Were vertebrates octoploid? , 2002, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[37] S. Jazwinski,et al. Distinct roles of processes modulated by histone deacetylases Rpd3p, Hda1p, and Sir2p in life extension by caloric restriction in yeast , 2002, Experimental Gerontology.
[38] Matthias Blüher,et al. Extended Longevity in Mice Lacking the Insulin Receptor in Adipose Tissue , 2003, Science.
[39] S. Woods,et al. Central nervous system control of food intake , 2000, Nature.
[40] Cynthia Kenyon,et al. Signals from the reproductive system regulate the lifespan of C. elegans , 1999, Nature.
[41] M. Tatar,et al. The demography of slow aging in male and female Drosophila mutant for the insulin‐receptor substrate homologue chico , 2002, Aging cell.
[42] A. Force,et al. Preservation of duplicate genes by complementary, degenerative mutations. , 1999, Genetics.
[43] T. Johnson,et al. daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans , 2001, Current Biology.
[44] P. L. Larsen. Aging and resistance to oxidative damage in Caenorhabditis elegans. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[45] Marc Tatar,et al. Chaperoning extended life , 1997, Nature.
[46] F. Dominici,et al. Increased insulin sensitivity and upregulation of insulin receptor, insulin receptor substrate (IRS)-1 and IRS-2 in liver of Ames dwarf mice. , 2002, The Journal of endocrinology.
[47] Andrzej Bartke,et al. Dwarf mice and the ageing process , 1996, Nature.
[48] D. Riddle,et al. Genes that regulate both development and longevity in Caenorhabditis elegans. , 1995, Genetics.
[49] Richard A. Miller,et al. Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[50] E. Hafen,et al. Extension of Life-Span by Loss of CHICO, a Drosophila Insulin Receptor Substrate Protein , 2001, Science.
[51] A. Bartke,et al. Reduced Levels of Thyroid Hormones, Insulin, and Glucose, and Lower Body Core Temperature in the Growth Hormone Receptor/Binding Protein Knockout Mouse , 2001, Experimental biology and medicine.
[52] T. W. Moon,et al. Insulin, insulin-like growth factor-I (IGF-I) and glucagon: the evolution of their receptors. , 1999, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
[53] Pier Paolo Pandolfi,et al. The p66shc adaptor protein controls oxidative stress response and life span in mammals , 1999, Nature.
[54] L. Partridge,et al. Interpreting interactions between treatments that slow aging , 2002, Aging cell.
[55] J. Apfeld,et al. Cell Nonautonomy of C. elegans daf-2 Function in the Regulation of Diapause and Life Span , 1998, Cell.
[56] H. Ooka,et al. Pituitary-thyroid activity and longevity in neonatally thyroxine-treated rats , 1983, Mechanisms of Ageing and Development.
[57] S. R. Datta,et al. DNA Repair Pathway Stimulated by the Forkhead Transcription Factor FOXO3a Through the Gadd45 Protein , 2002, Science.
[58] M. Bownes,et al. Control of oocyte maturation in sexually mature Drosophila females. , 1999, Developmental biology.
[59] R. Hosono,et al. Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot‐2 (mortalin)/mthsp70/Grp75 , 2002, FEBS letters.
[60] G. Bray,et al. Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.
[61] Koutarou D. Kimura,et al. Regulation of C. elegans life-span by insulinlike signaling in the nervous system. , 2000, Science.