A point mutation in the last intron responsible for increased expression and transforming activity of the c-Ha-ras oncogene
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[1] J. Sambrook,et al. Molecular Cloning: A Laboratory Manual , 2001 .
[2] S. Rosenberg,et al. Important advances in oncology 1986 , 1994 .
[3] A. Levinson,et al. High-level expression of c-H-ras1 fails to fully transform rat-1 cells , 1988, Molecular and cellular biology.
[4] R. Gelinas,et al. A fetal globin gene mutation in A gamma nondeletion hereditary persistence of fetal hemoglobin increases promoter strength in a nonerythroid cell , 1988, Molecular and cellular biology.
[5] C. Marshall,et al. Activated N-ras controls the transformed phenotype of HT1080 human fibrosarcoma cells , 1987, Cell.
[6] M. Groudine,et al. Mutations in the first exon are associated with altered transcription of c-myc in Burkitt lymphoma. , 1987, Science.
[7] Y. Kan,et al. Detection of sickle cell anaemia and thalassaemias , 1987, Nature.
[8] S. Weissman,et al. Expression of the affected A gamma globin gene associated with Greek nondeletion hereditary persistence of fetal hemoglobin , 1987, Molecular and cellular biology.
[9] D. Spandidos,et al. Transcriptional enhancer activity in the variable tandem repeat DNA sequence downstream of the human Ha‐ras1 gene , 1987, FEBS letters.
[10] E. Racker,et al. Opposing effects of a ras oncogene on growth factor-stimulated phosphoinositide hydrolysis: desensitization to platelet-derived growth factor and enhanced sensitivity to bradykinin. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[11] B. Wasylyk,et al. The c-Ha-ras oncogene and a tumor promoter activate the polyoma virus enhancer , 1987, Cell.
[12] D. Moore,et al. Human growth hormone as a reporter gene in regulation studies employing transient gene expression , 1986, Molecular and cellular biology.
[13] D. Goeddel,et al. Expression in rat fibroblasts of a human transforming growth factor-α cDNA results in transformation , 1986, Cell.
[14] R. Weinberg,et al. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts , 1986, Molecular and cellular biology.
[15] P. Chambon,et al. A mutated polyoma virus enhancer which is active in undifferentiated embryonal carcinoma cells is not repressed by adenovirus-2 E1A products , 1986, Nature.
[16] R. Myers,et al. Fine structure genetic analysis of a beta-globin promoter. , 1986, Science.
[17] B. Franza,et al. In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes , 1986, Cell.
[18] I. Pastan,et al. Promoter region of the human Harvey ras proto-oncogene: similarity to the EGF receptor proto-oncogene promoter. , 1985, Science.
[19] K. Mullis,et al. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. , 1985, Science.
[20] M. Barbacid,et al. ras gene Amplification and malignant transformation , 1985, Molecular and cellular biology.
[21] L. Kedes,et al. Evolution of the functional human beta-actin gene and its multi-pseudogene family: conservation of noncoding regions and chromosomal dispersion of pseudogenes , 1985, Molecular and cellular biology.
[22] P. Rigby,et al. Negative regulation of viral enhancers in undifferentiated embryonic stem cells , 1985, Cell.
[23] B. Stillman,et al. Replication and supercoiling of simian virus 40 DNA in cell extracts from human cells , 1985, Molecular and cellular biology.
[24] Michael Boshart,et al. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus , 1985, Cell.
[25] R. Kaufman. Identification of the components necessary for adenovirus translational control and their utilization in cDNA expression vectors. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[26] P. Seeburg,et al. Biological properties of human c-Ha-ras1 genes mutated at codon 12 , 1984, Nature.
[27] M. Kraus,et al. A position 12-activated H-ras oncogene in all HS578T mammary carcinosarcoma cells but not normal mammary cells of the same patient. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[28] D. Goeddel,et al. Comparative biochemical properties of normal and activated human ras p21 protein , 1984, Nature.
[29] D. Spandidos,et al. Malignant transformation of early passage rodent cells by a single mutated human oncogene , 1984, Nature.
[30] H. Ruley. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture , 1983, Nature.
[31] R. Newbold,et al. Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene , 1983, Nature.
[32] Robert A. Weinberg,et al. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes , 1983, Nature.
[33] E. Reddy,et al. Nucleotide sequence analysis of the T24 human bladder carcinoma oncogene. , 1983, Science.
[34] E. Chen,et al. Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue , 1983, Nature.
[35] A. Levinson,et al. Plasmid-directed synthesis of hepatitis B surface antigen in monkey cells , 1983, Molecular and cellular biology.
[36] Kenji Shimizu,et al. Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change , 1982, Nature.
[37] Eugenio Santos,et al. A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene , 1982, Nature.
[38] Cori Bargmann,et al. Mechanism of activation of a human oncogene , 1982, Nature.
[39] S. McKnight,et al. Transcriptional control signals of a eukaryotic protein-coding gene. , 1982, Science.
[40] D. Lowy,et al. Tumorigenic transformation of mammalian cells induced by a normal human gene homologous to the oncogene of Harvey murine sarcoma virus , 1982, Nature.
[41] Stephen M. Mount,et al. A catalogue of splice junction sequences. , 1982, Nucleic acids research.
[42] D. Moore,et al. Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. , 1981, Nucleic acids research.
[43] E. L. Springer,et al. Two syngeneic cell lines from human breast tissue: the aneuploid mammary epithelial (Hs578T) and the diploid myoepithelial (Hs578Bst) cell lines. , 1977, Journal of the National Cancer Institute.
[44] A. van der Eb,et al. A new technique for the assay of infectivity of human adenovirus 5 DNA. , 1973, Virology.
[45] Henry A. Erlich,et al. Characterization of β-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA , 1987, Nature.
[46] M. Aebi,et al. Precision and orderliness in splicing , 1987 .
[47] A. Godwin,et al. Regulation of a metallothionein-rasT24 fusion gene by zinc results in graded alterations in cell morphology and growth. , 1987, Oncogene.
[48] A. Levinson,et al. A repetitive sequence element 3′ of the human c‐Ha‐ras1 gene has enhancer activity , 1987, Journal of cellular physiology. Supplement.
[49] C. Benjamin,et al. Loss of platelet-derived growth factor-stimulated phospholipase activity in NIH-3T3 cells expressing the EJ-ras oncogene. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[50] J. Rhim,et al. Ha-ras oncogenes are activated by somatic alterations in human urinary tract tumours , 1984, Nature.
[51] H. Varmus. The molecular genetics of cellular oncogenes. , 1984, Annual review of genetics.