N-Substituted-3-alkoxy-derivatives of dextromethorphan are functional NMDA receptor antagonists in vivo: Evidence from an NMDA-induced seizure model in rats
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[1] M. Hall,et al. The Opioid Crisis and the Future of Addiction and Pain Therapeutics , 2019, The Journal of Pharmacology and Experimental Therapeutics.
[2] S. Bergese,et al. A comprehensive literature review , 2019 .
[3] T. Gould,et al. Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms , 2018, Pharmacological Reviews.
[4] J. Witkin,et al. Rapid-Acting Antidepressants. , 2018, Current pharmaceutical design.
[5] Joshua B. Ewen,et al. Randomized open-label trial of dextromethorphan in Rett syndrome , 2017, Neurology.
[6] R. Matsumoto,et al. Deuterated (d6)-dextromethorphan elicits antidepressant-like effects in mice , 2017, Pharmacology Biochemistry and Behavior.
[7] M. Ghasemi,et al. Mechanisms of action and clinical efficacy of NMDA receptor modulators in mood disorders , 2017, Neuroscience & Biobehavioral Reviews.
[8] B. Lucke-Wold,et al. Behavioral and biochemical effects of ketamine and dextromethorphan relative to its antidepressant-like effects in Swiss Webster mice , 2016, Neuroreport.
[9] E. Lauterbach. Treatment Resistant Depression with Loss of Antidepressant Response: Rapid-Acting Antidepressant Action of Dextromethorphan, A Possible Treatment Bridging Molecule. , 2016, Psychopharmacology bulletin.
[10] S. Traynelis,et al. Pharmacology of dextromethorphan: Relevance to dextromethorphan/quinidine (Nuedexta®) clinical use. , 2016, Pharmacology & therapeutics.
[11] Kelan Thomas,et al. Dextromethorphan: An update on its utility for neurological and neuropsychiatric disorders. , 2016, Pharmacology & therapeutics.
[12] Jang-Han Lee,et al. The Effects of Long-Term Ketamine Treatment on Cognitive Function in Complex Regional Pain Syndrome: A Preliminary Study. , 2016, Pain medicine.
[13] R. Matsumoto,et al. Involvement of AMPA receptors in the antidepressant-like effects of dextromethorphan in mice , 2015, Behavioural Brain Research.
[14] Pierre N Tariot,et al. Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial. , 2015, JAMA.
[15] Allison C. Nugent,et al. Ketamine and other N-methyl-D-aspartate receptor antagonists in the treatment of depression: a perspective review , 2015, Therapeutic advances in chronic disease.
[16] K. Chen,et al. A Placebo-Controlled Trial of Dextromethorphan as an Adjunct in Opioid-Dependent Patients Undergoing Methadone Maintenance Treatment , 2015, The international journal of neuropsychopharmacology.
[17] Daniel Z Lieberman,et al. The utility of the combination of dextromethorphan and quinidine in the treatment of bipolar II and bipolar NOS. , 2014, Journal of affective disorders.
[18] R. Matsumoto,et al. Involvement of Sigma-1 Receptors in the Antidepressant-like Effects of Dextromethorphan , 2014, PloS one.
[19] S. Amiri,et al. The Therapeutic Effect of Adding Dextromethorphan to Clonidine for Reducing Symptoms of Opioid Withdrawal: A Randomized Clinical Trial , 2013, ISRN psychiatry.
[20] Wang-Tso Lee,et al. Dextromethorphan in the treatment of early myoclonic encephalopathy evolving into migrating partial seizures in infancy. , 2012, Journal of the Formosan Medical Association = Taiwan yi zhi.
[21] S. Schachter,et al. The NMDA receptor complex as a therapeutic target in epilepsy: a review , 2011, Epilepsy & Behavior.
[22] J. Witkin. Commentary [the mood in the field of antidepressant drug discovery]. , 2011, CNS & neurological disorders drug targets.
[23] Jeffrey Cummings,et al. Dextromethorphan Plus Ultra Low‐Dose Quinidine Reduces Pseudobulbar Affect , 2010, Annals of neurology.
[24] P. Skolnick,et al. Glutamate-based antidepressants: 20 years on. , 2009, Trends in pharmacological sciences.
[25] Suneil K. Kalia,et al. NMDA receptors in clinical neurology: excitatory times ahead , 2008, The Lancet Neurology.
[26] Paul J Carlson,et al. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. , 2006, Archives of general psychiatry.
[27] F. Tortella,et al. Attenuation of the stimulant and convulsant effects of cocaine by 17-substituted-3-hydroxy and 3-alkoxy derivatives of dextromethorphan , 2003, Pharmacology Biochemistry and Behavior.
[28] D. Hewitt. The Use of NMDA‐Receptor Antagonists in the Treatment of Chronic Pain , 2000, The Clinical journal of pain.
[29] John H Krystal,et al. Antidepressant effects of ketamine in depressed patients , 2000, Biological Psychiatry.
[30] V. Mirtsou-Fidani,et al. A phase I clinical trial of dextromethorphan in intractable partial epilepsy. , 1999, Methods and findings in experimental and clinical pharmacology.
[31] J. Witkin,et al. Behavioral effects and anticonvulsant efficacies of low-affinity, uncompetitive NMDA antagonists in mice , 1999, Psychopharmacology.
[32] W. Danysz,et al. Low-affinity NMDA receptor channel blockers inhibit acquisition of intravenous morphine self-administration in naive mice. , 1999, European journal of pharmacology.
[33] C. Parsons,et al. Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data , 1999, Neuropharmacology.
[34] F. Tortella,et al. Anticonvulsant efficacy of N-methyl-D-aspartate antagonists against convulsions induced by cocaine. , 1999, The Journal of pharmacology and experimental therapeutics.
[35] C. Parsons,et al. Amino-alkyl-cyclohexanes are novel uncompetitive NMDA receptor antagonists with strong voltage-dependency and fast blocking kinetics: in vitro and in vivo characterization , 1999, Neuropharmacology.
[36] P. Popik,et al. Opiate withdrawal with dextromethorphan. , 1997, The American journal of psychiatry.
[37] F. Vocci,et al. The Effects of NMDA Receptor Antagonists and Nitric Oxide Synthase Inhibitors on Opioid Tolerance and Withdrawal , 1995, Neuropsychopharmacology.
[38] J. Witkin,et al. Sensitive and rapid behavioral differentiation ofN-methyl-d-aspartate receptor antagonists , 1994, Psychopharmacology.
[39] F. Tortella,et al. Novel anticonvulsant analogs of dextromethorphan: improved efficacy, potency, duration and side-effect profile. , 1994, The Journal of pharmacology and experimental therapeutics.
[40] F. Tortella,et al. Synthesis and evaluation of 3-substituted 17-methylmorphinan analogs as potential anticonvulsant agents. , 1992, Journal of medicinal chemistry.
[41] J. Leander,et al. The behavioral pharmacology of NMDA receptor antagonists. , 1990, Trends in pharmacological sciences.
[42] P. Skolnick,et al. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. , 1990, European journal of pharmacology.
[43] J. Bormann,et al. Memantine displaces [3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex. , 1989, European journal of pharmacology.
[44] M. Pontecorvo,et al. Dextromethorphan inhibits NMDA-induced convulsions. , 1988, European journal of pharmacology.
[45] P. Ornstein,et al. N-Methyl-d-aspartic acid-induced lethality in mice: selective antagonism by phencylidine-like drugs , 1988, Brain Research.
[46] F. Wilcoxon,et al. A simplified method of evaluating dose-effect experiments. , 1948, The Journal of pharmacology and experimental therapeutics.
[47] P. Reddy,et al. Role of Glutamate and NMDA Receptors in Alzheimer's Disease. , 2017, Journal of Alzheimer's disease : JAD.
[48] M. Chamanara,et al. The role of NMDA receptor and nitric oxide/cyclic guanosine monophosphate pathway in the antidepressant-like effect of dextromethorphan in mice forced swimming test and tail suspension test. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[49] T. Reisine. Opioid analgesics and antagonists , 1996 .
[50] H. Wieser,et al. Improvement of medically refractory temporal lobe epilepsy with dextromethorphan , 1992 .
[51] F. Tortella,et al. Modulators of N-methyl-D-aspartate protect against diazepam- or phenobarbital-resistant cocaine convulsions. , 1991, Life sciences.