Anti-apoptotic treatments prevent cartilage degradation after acute trauma to human ankle cartilage.

[1]  B. Morrey BMP-7 Protects Against Progression of Cartilage Degeneration after Impact Injury , 2010 .

[2]  F. Guilak,et al.  Viability and apoptosis of human chondrocytes in osteochondral fragments following joint trauma. , 2007, The Journal of bone and joint surgery. British volume.

[3]  Thomas D Brown,et al.  Posttraumatic Osteoarthritis: A First Estimate of Incidence, Prevalence, and Burden of Disease , 2006, Journal of orthopaedic trauma.

[4]  A. Dang,et al.  Beneficial effects of intra-articular caspase inhibition therapy following osteochondral injury. , 2006, Osteoarthritis and cartilage.

[5]  D. D’Lima,et al.  Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis. , 2006, Arthritis and rheumatism.

[6]  M. Davies,et al.  Validation of an in vitro single‐impact load model of the initiation of osteoarthritis‐like changes in articular cartilage , 2006, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[7]  M. Hurtig,et al.  Characterization of experimentally induced post-traumatic osteoarthritis in the medial femorotibial joint of horses. , 2006, American journal of veterinary research.

[8]  T. Schwenke,et al.  Application of reproducible impulse loading to study osteochondral grafting procedures , 2006 .

[9]  R. Haut,et al.  The limitation of acute necrosis in retro‐patellar cartilage after a severe blunt impact to the in vivo rabbit patello‐femoral joint , 2005, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[10]  P. Torzilli,et al.  Influence of stress rate on water loss, matrix deformation and chondrocyte viability in impacted articular cartilage. , 2005, Journal of biomechanics.

[11]  T. Oegema,et al.  Role of acute trauma in development of osteoarthritis , 1993, Agents and Actions.

[12]  R. Haut,et al.  The use of a non‐ionic surfactant (P188) to save chondrocytes from necrosis following impact loading of chondral explants , 2004, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[13]  Marna Ericson,et al.  Cell death after cartilage impact occurs around matrix cracks , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[14]  H T Kim,et al.  Chondrocyte apoptosis following intraarticular fracture in humans. , 2002, Osteoarthritis and cartilage.

[15]  Raphael C. Lee,et al.  Direct observation of poloxamer 188 insertion into lipid monolayers. , 2002, Biophysical journal.

[16]  R. Loeser,et al.  Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. , 2002, Arthritis and rheumatism.

[17]  G. Lust,et al.  Intercellular signaling as a cause of cell death in cyclically impacted cartilage explants. , 2001, Osteoarthritis and cartilage.

[18]  D. D’Lima,et al.  Human chondrocyte apoptosis in response to mechanical injury. , 2001, Osteoarthritis and cartilage.

[19]  G. Lust,et al.  Chondrocyte necrosis and apoptosis in impact damaged articular cartilage , 2001, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[20]  C. Archer,et al.  The reactions of articular cartilage to experimental wounding: role of apoptosis. , 2000, Arthritis and rheumatism.

[21]  P. Torzilli,et al.  Effect of impact load on articular cartilage: cell metabolism and viability, and matrix water content. , 1999, Journal of biomechanical engineering.

[22]  Y. Lazebnik,et al.  Caspases: enemies within. , 1998, Science.

[23]  F. Blanco,et al.  Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology. , 1998, Arthritis and rheumatism.

[24]  K. Kuettner,et al.  Prevalence of degenerative morphological changes in the joints of the lower extremity. , 1997, Osteoarthritis and cartilage.

[25]  K. Kuettner,et al.  Biochemistry of articular cartilage in health and disease. , 1992, Clinical biochemistry.

[26]  H. Dorfman,et al.  Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. , 1971, The Journal of bone and joint surgery. American volume.

[27]  L. Rosenberg Chemical basis for the histological use of safranin O in the study of articular cartilage. , 1971, The Journal of bone and joint surgery. American volume.