Cutaneous T cell lymphoma associated with recurrent panniculitis and reactive histiocytosis.

As is the case in other areas of research where advances in basic science have changed concepts in clinical medicine, it has become evident that clinical or morphological criteria alone no longer suffice to classify lymphocytic neoplasms. A definition of the subclass of the cells involved, their immunocytochemical characteristics, and their original role in the immune system appears necessary to arrive at more accurate diagnosis, prognosis, and more appropriate treatment for this group of diseases.