Experimental study of intraperitoneal suramin on the healing of colonic anastomoses

The effect of the antiangiogenic agent suramin on the healing of colonic anastomoses was studied in a rat model.

[1]  L. Ellis,et al.  p53, vessel count, and vascular endothelial growth factor expression in human colon cancer , 1998, International journal of cancer.

[2]  R. Scheuermann,et al.  Cancer dormancy: Opportunities for new therapeutic approaches , 1997, Nature Medicine.

[3]  S. Fox,et al.  Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. , 1996, European journal of cancer.

[4]  V. Hombach,et al.  Suramin is a potent inhibitor of vascular endothelial growth factor. A contribution to the molecular basis of its antiangiogenic action. , 1996, Journal of molecular and cellular cardiology.

[5]  D. Danforth,et al.  Postoperative complications in patients receiving suramin therapy. , 1994, Surgery.

[6]  W Blumenfeld,et al.  Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. , 1993, The American journal of pathology.

[7]  C. Stein,et al.  Suramin: a novel antineoplastic agent with multiple potential mechanisms of action. , 1993, Cancer research.

[8]  F. Sola,et al.  Suramin prevents neovascularisation and tumour growth through blocking of basic fibroblast growth factor activity. , 1992, British Journal of Cancer.

[9]  H. Gralnick,et al.  The Effect of Suramin on Laboratory Tests of Coagulation , 1992, Thrombosis and Haemostasis.

[10]  J. Folkman,et al.  Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma. , 1991, The New England journal of medicine.

[11]  M. Dalakas,et al.  Suramin‐induced polyneuropathy , 1990, Neurology.

[12]  M. Fukushima,et al.  Differential inhibition of various deoxyribonucleic and ribonucleic acid polymerases by suramin. , 1988, European journal of biochemistry.

[13]  T. Hendriks,et al.  Wound healing in the intestinal wall , 1984, Diseases of the colon and rectum.

[14]  B. Cragg,et al.  Experimental animal model for mucopolysaccharidosis: suramin-induced glycosaminoglycan and sphingolipid accumulation in the rat. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[15]  T. K. Hunt,et al.  Effect of Malnutrition on Colonic Healing , 1974, Annals of surgery.

[16]  C. Loveday,et al.  Effects of suramin on complement, blood clotting, fibrinolysis and kinin formation , 1973, British journal of pharmacology.