The double spike toolbox

The double spike technique is a well established method for correcting for instrumental mass fractionation in mass spectrometry. The precision of the technique is controlled by the choices of double spike composition and the proportions in which the double spike and sample are mixed. To make these choices easier, we provide software (“the double spike toolbox”) for calculating optimal double spikes, which are chosen purely on the basis of minimising error propagation. In addition, we provide “cocktail lists” of optimal double spikes for all 33 elements that have 4 or more naturally occurring isotopes, using some sensible default parameters. As examples, we discuss the application of the software to Fe, Pb, and Ca isotopes.

[1]  K. Gopalan,et al.  Evaluation of a 42Ca–43Ca double-spike for high precision Ca isotope analysis , 2006 .

[2]  T. Tombrello,et al.  Ca isotope fractionation on the Earth and other solar system materials , 1978 .

[3]  A. Hofmann.  Fractionation corrections for mixed-isotope spikes of Sr, K, and Pb , 1971 .

[4]  F. Albarède,et al.  Analytical Methods for Non-Traditional Isotopes , 2004 .

[5]  H. Thode,et al.  Variations in the S33, S34, and S36 contents of meteorites and their relation to chemical and nuclear effects , 1965 .

[6]  B. Beard,et al.  Correction of instrumentally produced mass fractionation during isotopic analysis of fe by thermal ionization mass spectrometry , 1999 .

[7]  A. Galy,et al.  Kinetic and equilibrium mass-dependent isotope fractionation laws in nature and their geochemical and cosmochemical significance , 2002 .

[8]  M. Fantle,et al.  Essentials of iron, chromium, and calcium isotope analysis of natural materials by thermal ionization mass spectrometry , 2009 .

[9]  D. DePaolo.  Calcium isotopic variations produced by biological, kinetic, radiogenic and nucleosynthetic processes , 2004 .

[10]  C. Jeandel,et al.  Measurement of the isotopic composition of dissolved iron in the open ocean , 2008 .

[11]  F. Poitrasson,et al.  Applications of non-traditional stable isotopes in high-temperature geochemistry , 2009 .

[12]  Simon M. Nelms,et al.  Inductively coupled plasma mass spectrometry handbook , 2005 .

[13]  R. Russell.  The systematics of double spiking , 1971 .

[14]  G. L. Cumming.  Propagation of experimental errors in lead isotope ratio measurements using the double spike method , 1973 .

[15]  M. H. Dodson.  A theoretical study of the use of internal standards for precise isotopic analysis by the surface ionization technique: Part I - General first-order algebraic solutions , 1963 .

[16]  P. D. P. Taylor,et al.  Isotopic Compositions of the Elements 1997 , 1998 .

[17]  K. Gopalan,et al.  High Precision Determination of 48Ca/42Ca Ratio by TIMS for Ca Isotope Fractionation Studies , 2007 .

[18]  M. H. Dodson.  Simplified equations for double-spiked isotopic analyses , 1970 .

[19]  M. Thirlwall,et al.  An assessment of mass discrimination in MC-ICPMS using Nd isotopes , 2002 .

[20]  M. H. Dodson.  A theoretical study of the use of internal standards for precise isotopic analysis by the surface ionization technique Part II: Error relationships , 1969 .

[21]  F. Albarède,et al.  Precise and accurate isotopic measurements using multiple-collector ICPMS 1 1 Associate editor: Y. Amelin , 2004 .

[22]  M. Thirlwall,et al.  Multidynamic isotope ratio analysis using MC–ICP–MS and the causes of secular drift in Hf, Nd and Pb isotope ratios , 2004 .

[23]  S. Galer.  Optimal double and triple spiking for high precision lead isotopic measurement , 1999 .

[24]  Diane Beauchemin.  Inductively coupled plasma mass spectrometry handbook , 2007, Journal of the American Society for Mass Spectrometry.

[25]  W. Compston,et al.  Lead isotopic analysis using a double spike , 1969 .

[26]  D. Papanastassiou,et al.  Calcium isotope fractionation in ion-exchange chromatography , 1978 .

[27]  M. Thirlwall.  Multicollector ICP-MS analysis of Pb isotopes using a 207pb-204pb double spike demonstrates up to 400 ppm/amu systematic errors in Tl-normalization , 2002 .

[28]  R. Carlson,et al.  High precision iron isotope measurements of meteoritic material by cold plasma ICP-MS , 2003 .

[29]  G. Manhès,et al.  Precise lead isotope measurements by the double spike technique: A reconsideration , 1985 .