Susceptibility of non-enveloped DNA- and RNA-type viruses to photodynamic inactivation

The comparative susceptibility of DNA- and RNA-type viruses to photodynamic inactivation has not yet been clearly addressed. In this study the effect of the tricationic porphyrin Tri-Py^+-Me-PF on the inactivation of four DNA and three RNA non-enveloped phages was compared. The results obtained show that the photodynamic efficiency varied with the phage type, the RNA-type phages being much more easily photoinactivated than the DNA-type ones.

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