High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1
暂无分享,去创建一个
A Sewing | A C Lloyd | A. Lloyd | A. Sewing | B. Wiseman | H. Land | H Land | B Wiseman | Bryony Wiseman | Alison C. Lloyd | B. Wiseman | A. C. Lloyd
[1] A. Ogura,et al. Sarcoma viruses carrying ras oncogenes induce differentiation-associated properties in a neuronal cell line , 1985, Nature.
[2] C. Marshall,et al. Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation , 1995, Cell.
[3] S. Goff,et al. Retroviral Gene Transfer Using Safe and Efficient Packaging Cell Lines , 1990, Annals of the New York Academy of Sciences.
[4] C. Marshall,et al. MAP kinase kinase kinase, MAP kinase kinase and MAP kinase. , 1994, Current opinion in genetics & development.
[5] M. McMahon,et al. Inhibition of platelet-derived growth factor- and epidermal growth factor-mediated mitogenesis and signaling in 3T3 cells expressing delta Raf-1:ER, an estradiol-regulated form of Raf-1 , 1994, Molecular and cellular biology.
[6] X. Breakefield,et al. Self-contained, tetracycline-regulated retroviral vector system for gene delivery to mammalian cells , 1996, Journal of virology.
[7] F. Di Cunto,et al. The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression. , 1996, Genes & development.
[8] P. Cohen,et al. Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases , 1991, Nature.
[9] I. Herskowitz,et al. Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2 , 1990, Cell.
[10] A. Brunet,et al. Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts , 1993, The Journal of cell biology.
[11] Y. Wang,et al. Regulation of the cell cycle machinery by oncogenic ras. , 1996, Oncogene.
[12] Andreas Sewing,et al. Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27Kip1 binding to newly formed complexes , 1997, Oncogene.
[13] K. Walsh,et al. MyoD-induced expression of p21 inhibits cyclin-dependent kinase activity upon myocyte terminal differentiation , 1995, Molecular and cellular biology.
[14] M. Weber,et al. Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase. , 1993, Science.
[15] Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product , 1985 .
[16] S. Lowe,et al. Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a , 1997, Cell.
[17] M. Noble,et al. Ras‐mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. , 1988, The EMBO journal.
[18] S. Elledge,et al. Inhibition of cyclin-dependent kinases by p21. , 1995, Molecular biology of the cell.
[19] H. Herzog,et al. cDNA encoding the human homologue of rat ribosomal protein L35a. , 1990, Nucleic acids research.
[20] P. Cohen,et al. EGF triggers neuronal differentiation of PC12 cells that overexpress the EGF receptor , 1994, Current Biology.
[21] S. Shurtleff,et al. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. , 1993, Genes & development.
[22] Kung,et al. Induction of transformation and DNA synthesis after microinjection of raf proteins , 1990, Molecular and cellular biology.
[23] K. Kinzler,et al. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. , 1995, Genes & development.
[24] Xiao-Fan Wang,et al. Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[25] Miller Ad,et al. Improved Retroviral Vectors for Gene Transfer and Expression , 1989 .
[26] M. McMahon,et al. Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase , 1993, Molecular and cellular biology.
[27] Yi-Song Wang,et al. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. , 1994, Cancer research.
[28] S. Decker. Nerve Growth Factor-induced Growth Arrest and Induction of p21 in NIH-3T3 Cells Expressing TrkA (*) , 1995, The Journal of Biological Chemistry.
[29] E. Wilson,et al. Androgen receptor phosphorylation, turnover, nuclear transport, and transcriptional activation. Specificity for steroids and antihormones. , 1992, The Journal of biological chemistry.
[30] S. Ng,et al. Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells , 1995, Molecular and cellular biology.
[31] M. Gorospe,et al. Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway. , 1996, Cancer research.
[32] J. R. Smith,et al. CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein. , 1996, Genes & development.
[33] Philip R. Cohen,et al. MAP kinase activator from insulin‐stimulated skeletal muscle is a protein threonine/tyrosine kinase. , 1992, The EMBO journal.
[34] A. Levine,et al. Cyclin D1 and p21/waf1 are both involved in p53 growth suppression. , 1996, Oncogene.
[35] E. Hafen,et al. The sevenless signalling cassette mediates Drosophila EGF receptor function during epidermal development. , 1994, Development.
[36] M. Ewen,et al. Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein , 1997, Nature.
[37] T. Graf,et al. v-mil induces autocrine growth and enhanced tumorigenicity in v-myc-transformed avian macrophages , 1986, Cell.
[38] F. C. Lucibello,et al. Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP. , 1993, Journal of cell science.
[39] A. Miller,et al. Improved retroviral vectors for gene transfer and expression. , 1989, BioTechniques.
[40] F. Cross,et al. Ste12 and Mcm1 regulate cell cycle-dependent transcription of FAR1 , 1996, Molecular and cellular biology.
[41] T. Metz,et al. Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes , 1995, Cell.
[42] R. Lurz,et al. Two unrelated cell‐derived sequences in the genome of avian leukemia and carcinoma inducing retrovirus MH2. , 1983, EMBO Journal.
[43] Jonathan A. Cooper,et al. Mammalian Ras interacts directly with the serine/threonine kinase raf , 1993, Cell.
[44] Y. Ueyama,et al. B-raf, a new member of the raf family, is activated by DNA rearrangement , 1988, Molecular and cellular biology.
[45] M. Pagano,et al. Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines. , 1994, Oncogene.
[46] R. Hipskind,et al. v-raf confers CSF-1 independent growth to a macrophage cell line and leads to immediate early gene expression without MAP-kinase activation. , 1993, Oncogene.
[47] Ivan Dikic,et al. PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation , 1994, Current Biology.
[48] A. Lloyd,et al. Cooperating oncogenes converge to regulate cyclin/cdk complexes. , 1997, Genes & development.
[49] James Brugarolas,et al. Radiation-induced cell cycle arrest compromised by p21 deficiency , 1995, Nature.
[50] P. Warne,et al. Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro , 1993, Nature.
[51] Gustav Ammerer,et al. FAR1 links the signal transduction pathway to the cell cycle machinery in yeast , 1993, Cell.
[52] R. Treisman,et al. Regulation of transcription by MAP kinase cascades. , 1996, Current opinion in cell biology.
[53] C. Marshall,et al. A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21ras. , 1993, The Journal of biological chemistry.
[54] C. Marshall,et al. Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells , 1994, Cell.
[55] F. C. Lucibello,et al. Deregulation of cyclins D1 and E and suppression of cdk2 and cdk4 in senescent human fibroblasts. , 1993, Journal of cell science.
[56] P. Cohen,et al. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. , 1992, The Biochemical journal.
[57] David L. Brautigan,et al. Raf-1 activates MAP kinase-kinase , 1992, Nature.
[58] M. Gossen,et al. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system. , 1994, Molecular and cellular biology.
[59] S. Reed,et al. Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[60] C. Marshall,et al. Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein , 1997, Current Biology.
[61] S. Leevers,et al. Activation of extracellular signal‐regulated kinase, ERK2, by p21ras oncoprotein. , 1992, The EMBO journal.
[62] Sally J. Leevers,et al. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane , 1994, Nature.
[63] H. Ruley. Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture , 1983, Nature.
[64] T. Bonner,et al. The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirus. , 1987, Nucleic acids research.
[65] A. Hayday,et al. Raf regulates positive selection , 1996, European journal of immunology.
[66] D. Lowy,et al. Function and regulation of ras. , 1993, Annual review of biochemistry.
[67] G. Blandino,et al. Interference with p53 protein inhibits hematopoietic and muscle differentiation , 1996, The Journal of cell biology.
[68] C. Pritchard,et al. Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells , 1995, Molecular and cellular biology.
[69] H. Land,et al. Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. , 1990, Nucleic acids research.
[70] K. Pumiglia,et al. Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[71] E. Nishida,et al. Xenopus MAP kinase activator is a serine/threonine/tyrosine kinase activated by threonine phosphorylation. , 1992, The EMBO journal.
[72] G. Guroff,et al. Nerve growth factor-induced alteration in the response of PC12 pheochromocytoma cells to epidermal growth factor , 1981, The Journal of cell biology.
[73] Stephen J. Elledge,et al. Mice Lacking p21 CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control , 1995, Cell.
[74] E. Lees,et al. Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1 , 1997, Molecular and cellular biology.
[75] Robert A. Weinberg,et al. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes , 1983, Nature.
[76] J. Trent,et al. WAF1, a potential mediator of p53 tumor suppression , 1993, Cell.
[77] Xin-Yuan Fu,et al. Activation of Statl by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism , 1997, Nature.
[78] R. Weinberg,et al. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters , 1985, Nature.
[79] G. Stamp,et al. Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. , 1995, Genes & development.
[80] P. Cohen,et al. Activation of the MAP kinase pathway by the protein kinase raf , 1992, Cell.
[81] J. Southgate,et al. Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ , 1989, Cell.
[82] W. Rutter,et al. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. , 1979, Biochemistry.
[83] J. Cleveland,et al. Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus , 1985, Nature.
[84] Thea D. Tlsty,et al. Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53 , 1992, Cell.
[85] G K Lewis,et al. Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product , 1985, Molecular and cellular biology.
[86] M. Levine,et al. Threshold responses to the dorsal regulatory gradient and the subdivision of primary tissue territories in the Drosophila embryo. , 1996, Current opinion in genetics & development.
[87] J. Blenis,et al. Nuclear localization and regulation of erk- and rsk-encoded protein kinases , 1992, Molecular and cellular biology.
[88] W. Kolch,et al. Raf-1 protein kinase is required for growth of induced NIH/3T3 cells , 1991, Nature.
[89] R. Müller,et al. Alternative splicing of human cyclin E. , 1994, Journal of cell science.
[90] C. Guillouf,et al. Induction of p21 (WAF-1/CIP1) during differentiation. , 1994, Oncogene.
[91] E. Krebs,et al. Multiple components in an epidermal growth factor-stimulated protein kinase cascade. In vitro activation of a myelin basic protein/microtubule-associated protein 2 kinase. , 1991, The Journal of biological chemistry.
[92] P. Savatier,et al. Effect of nerve growth factor on the expression of cell cycle regulatory proteins in PC12 cells: dissection of the neurotrophic response from the anti-mitogenic response. , 1996, Oncogene.
[93] T. Roberts,et al. The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[94] M. Dahmer,et al. Insulin and insulin-like growth factors stimulate deoxyribonucleic acid synthesis in PC12 pheochromocytoma cells. , 1988, Endocrinology.
[95] M. Freeman,et al. Cell determination strategies in the Drosophila eye. , 1997, Development.