Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues
暂无分享,去创建一个
Hae Kyung Im | Dan L Nicolae | Nancy J Cox | Kaanan P. Shah | Jonathon Brenner | Heather E Wheeler | Keston Aquino-Michaels | D. Nicolae | H. Im | H. Wheeler | K. Aquino-Michaels | J. Brenner | Kaanan P Shah | Tzintzuni Garcia | N. Cox | Tzintzuni I. Garcia | Jonathon Brenner
[1] P. Visscher,et al. Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets , 2016, Nature Genetics.
[2] Trevor Hastie,et al. Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent. , 2011, Journal of statistical software.
[3] Trevor Hastie,et al. Regularization Paths for Generalized Linear Models via Coordinate Descent. , 2010, Journal of statistical software.
[4] H. Zou,et al. Regularization and variable selection via the elastic net , 2005 .
[5] J. Marchini,et al. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing , 2012, Nature Genetics.
[6] Gonçalo R. Abecasis,et al. Minimac2: Faster Genotype Imputation , 2015, Bioinform..
[7] Adan Valladares-Salgado,et al. Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait. , 2014, American journal of human genetics.
[8] Han Xu,et al. Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases. , 2014, American journal of human genetics.
[9] D. Bates,et al. Fitting Linear Mixed-Effects Models Using lme4 , 2014, 1406.5823.
[10] T. Speed,et al. Summaries of Affymetrix GeneChip probe level data. , 2003, Nucleic acids research.
[11] Justin Zobel,et al. Performance and Robustness of Penalized and Unpenalized Methods for Genetic Prediction of Complex Human Disease , 2013, Genetic epidemiology.
[12] Andrew J. Hill,et al. Analysis of protein-coding genetic variation in 60,706 humans , 2015, bioRxiv.
[13] A. Long,et al. Genetic Dissection of the Drosophila melanogaster Female Head Transcriptome Reveals Widespread Allelic Heterogeneity , 2014, PLoS genetics.
[14] C. Wallace,et al. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics , 2013, PLoS genetics.
[15] Kaanan P. Shah,et al. A gene-based association method for mapping traits using reference transcriptome data , 2015, Nature Genetics.
[16] E. Dermitzakis,et al. Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations , 2010, PLoS genetics.
[17] Bronwen L. Aken,et al. GENCODE: The reference human genome annotation for The ENCODE Project , 2012, Genome research.
[18] M. Stephens,et al. A Statistical Framework for Joint eQTL Analysis in Multiple Tissues , 2012, PLoS genetics.
[19] Christopher D. Brown,et al. Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs , 2012, PLoS genetics.
[20] D. Koller,et al. Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals , 2013, Genome research.
[21] Robert L. Grossman,et al. The Design of a Community Science Cloud: The Open Science Data Cloud Perspective , 2012, 2012 SC Companion: High Performance Computing, Networking Storage and Analysis.
[22] Andrey A. Shabalin,et al. Matrix eQTL: ultra fast eQTL analysis via large matrix operations , 2011, Bioinform..
[23] Peter Kraft,et al. Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis , 2012, Nature Genetics.
[24] Alan M. Kwong,et al. A reference panel of 64,976 haplotypes for genotype imputation , 2015, Nature Genetics.
[25] Tanya M. Teslovich,et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes , 2012, Nature Genetics.
[26] Daniel Gianola,et al. Predicting genetic predisposition in humans: the promise of whole-genome markers , 2010, Nature Reviews Genetics.
[27] T. Lehtimäki,et al. Integrative approaches for large-scale transcriptome-wide association studies , 2015, Nature Genetics.
[28] R. Durbin,et al. Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses , 2012, Nature Protocols.
[29] Lude Franke,et al. Mediation Analysis Demonstrates That Trans-eQTLs Are Often Explained by Cis-Mediation: A Genome-Wide Analysis among 1,800 South Asians , 2014, PLoS genetics.
[30] P. Deloukas,et al. Patterns of Cis Regulatory Variation in Diverse Human Populations , 2012, PLoS genetics.
[31] Robert L. Grossman,et al. Bionimbus: a cloud for managing, analyzing and sharing large genomics datasets , 2014, J. Am. Medical Informatics Assoc..
[32] R. Tibshirani. Regression Shrinkage and Selection via the Lasso , 1996 .
[33] L. Kruglyak,et al. The role of regulatory variation in complex traits and disease , 2015, Nature Reviews Genetics.
[34] P. Visscher,et al. GCTA: a tool for genome-wide complex trait analysis. , 2011, American journal of human genetics.
[35] A. E. Hoerl,et al. Ridge Regression: Applications to Nonorthogonal Problems , 1970 .
[36] R Core Team,et al. R: A language and environment for statistical computing. , 2014 .
[37] Carson C Chow,et al. Second-generation PLINK: rising to the challenge of larger and richer datasets , 2014, GigaScience.
[38] N. Cox,et al. Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS , 2010, PLoS genetics.
[39] Hae Kyung Im,et al. Poly‐Omic Prediction of Complex Traits: OmicKriging , 2013, Genetic epidemiology.
[40] Eran Segal,et al. Robust Prediction of Expression Differences among Human Individuals Using Only Genotype Information , 2013, PLoS genetics.
[41] Jun S. Liu,et al. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans , 2015, Science.
[42] Alkes L. Price,et al. Single-Tissue and Cross-Tissue Heritability of Gene Expression Via Identity-by-Descent in Related or Unrelated Individuals , 2011, PLoS genetics.
[43] P. Visscher,et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder , 2009, Nature.
[44] Roby Joehanes,et al. Identification of common genetic variants controlling transcript isoform variation in human whole blood , 2015, Nature Genetics.
[45] Xia Yang,et al. Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS. , 2013, American journal of human genetics.
[46] P. Sullivan,et al. Heritability and Genomics of Gene Expression in Peripheral Blood , 2014, Nature Genetics.
[47] Justin O Borevitz,et al. Genetic architecture of regulatory variation in Arabidopsis thaliana. , 2011, Genome research.
[48] Xiang Zhou,et al. Polygenic Modeling with Bayesian Sparse Linear Mixed Models , 2012, PLoS genetics.
[49] Doug Speed,et al. Improved heritability estimation from genome-wide SNPs. , 2012, American journal of human genetics.
[50] John D. Storey,et al. Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis , 2007, PLoS genetics.
[51] O. Delaneau,et al. A linear complexity phasing method for thousands of genomes , 2011, Nature Methods.
[52] Joshua T. Burdick,et al. Mapping determinants of human gene expression by regional and genome-wide association , 2005, Nature.
[53] Benjamin D. Greenberg,et al. Partitioning the Heritability of Tourette Syndrome and Obsessive Compulsive Disorder Reveals Differences in Genetic Architecture , 2013, PLoS genetics.
[54] M. Stephens,et al. Genome-wide Efficient Mixed Model Analysis for Association Studies , 2012, Nature Genetics.
[55] Christopher D. Brown,et al. Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue , 2011, PLoS genetics.