Chitosan and Its Derivatives for Drug Delivery Perspective
暂无分享,去创建一个
[1] M. Rekha,et al. Bioadhesive hydrophobic chitosan microparticles for oral delivery of insulin: In vitro characterization and in vivo uptake studies , 2011 .
[2] C. Sharma,et al. In vitro evaluation of N-(2-hydroxy) propyl-3-trimethyl ammonium chitosan for oral insulin delivery , 2011 .
[3] Peter Wick,et al. Nanotoxicology: an interdisciplinary challenge. , 2011, Angewandte Chemie.
[4] R. Franke,et al. Inside Cover: A General and Efficient Iridium‐Catalyzed Hydroformylation of Olefins (Angew. Chem. Int. Ed. 1/2011) , 2011 .
[5] M. Veiga,et al. In vitro Evaluation of Acyclovir/Chitosan Floating Systems , 2010, Materials.
[6] W. Jiskoot,et al. Dual role of CpG as immune modulator and physical crosslinker in ovalbumin loaded N-trimethyl chitosan (TMC) nanoparticles for nasal vaccination. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[7] M. Rekha,et al. Dextran-protamine polycation: an efficient nonviral and haemocompatible gene delivery system. , 2010, Colloids and surfaces. B, Biointerfaces.
[8] M. Tabrizian,et al. Advances in using chitosan-based nanoparticles for in vitro and in vivo drug and gene delivery , 2010, Expert opinion on drug delivery.
[9] S. Jon,et al. A novel approach to oral delivery of insulin by conjugating with low molecular weight chitosan. , 2010, Bioconjugate chemistry.
[10] Shantikumar V. Nair,et al. Biomedical applications of chitin and chitosan based nanomaterials—A short review , 2010 .
[11] T. Yen,et al. Biodistribution, pharmacodynamics and pharmacokinetics of insulin analogues in a rat model: Oral delivery using pH-responsive nanoparticles vs. subcutaneous injection. , 2010, Biomaterials.
[12] A. Nokhodchi,et al. Development of pH-sensitive Insulin Nanoparticles using Eudragit L100-55 and Chitosan with Different Molecular Weights , 2010, AAPS PharmSciTech.
[13] D. K. Majumdar,et al. Eudragit S-100 entrapped chitosan microspheres of valdecoxib for colon cancer , 2010, Journal of materials science. Materials in medicine.
[14] S. Gu,et al. Thiolated trimethyl chitosan nanocomplexes as gene carriers with high in vitro and in vivo transfection efficiency. , 2010, Journal of controlled release : official journal of the Controlled Release Society.
[15] Sun‐mi Lee,et al. Galactosylated chitosan-g-PEI/DNA complexes-loaded poly(organophosphazene) hydrogel as a hepatocyte targeting gene delivery system , 2010, Archives of pharmacal research.
[16] M. Rekha,et al. Dextran-glycidyltrimethylammonium chloride conjugate/DNA nanoplex: A potential non-viral and haemocompatible gene delivery system. , 2010, International journal of pharmaceutics.
[17] C. Sharma,et al. Acyl modified chitosan derivatives for oral delivery of insulin and curcumin , 2010, Journal of materials science. Materials in medicine.
[18] C. Sharma,et al. Development and characterization of self-aggregated nanoparticles from anacardoylated chitosan as a carrier for insulin , 2010 .
[19] I. Aranaz,et al. Chitosan Amphiphilic Derivatives. Chemistry and Applications , 2010 .
[20] Miqin Zhang,et al. Chitosan-based hydrogels for controlled, localized drug delivery. , 2010, Advanced drug delivery reviews.
[21] Ick Chan Kwon,et al. Targeted delivery of low molecular drugs using chitosan and its derivatives. , 2010, Advanced drug delivery reviews.
[22] Lichen Yin,et al. Drug permeability and mucoadhesion properties of thiolated trimethyl chitosan nanoparticles in oral insulin delivery. , 2009, Biomaterials.
[23] G. Bhat,et al. The evaluation of a biodegradable dental chip containing chlorhexidine in chitosan base as a targeted drug delivery in the management of chronic periodontitis in patients , 2009 .
[24] C. Pillai,et al. Chitin and chitosan polymers: Chemistry, solubility and fiber formation , 2009 .
[25] Chandra P Sharma,et al. Synthesis and evaluation of lauryl succinyl chitosan particles towards oral insulin delivery and absorption. , 2009, Journal of controlled release : official journal of the Controlled Release Society.
[26] Hsing-Wen Sung,et al. In vivo evaluation of safety and efficacy of self-assembled nanoparticles for oral insulin delivery. , 2009, Biomaterials.
[27] Changren Zhou,et al. Polysaccharides-based nanoparticles as drug delivery systems. , 2008, Advanced drug delivery reviews.
[28] K. M. Lin,et al. Multi-ion-crosslinked nanoparticles with pH-responsive characteristics for oral delivery of protein drugs. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[29] M. Rekha,et al. Phthalyl Chitosan-Poly(ethylene oxide) Semi-Interpenetrating Polymer Network Microparticles for Oral Protein Delivery : An In Vitro Characterization , 2008 .
[30] P. Nydert,et al. Chitosan as a carrier for non‐viral gene transfer in a cystic‐fibrosis cell line , 2008, Biotechnology and applied biochemistry.
[31] M. Prabaharan. Review Paper: Chitosan Derivatives as Promising Materials for Controlled Drug Delivery , 2008, Journal of biomaterials applications.
[32] Yu-Hsin Lin,et al. Oral delivery of peptide drugs using nanoparticles self-assembled by poly(gamma-glutamic acid) and a chitosan derivative functionalized by trimethylation. , 2008, Bioconjugate chemistry.
[33] I. Bravo-Osuna,et al. Specific permeability modulation of intestinal paracellular pathway by chitosan-poly(isobutylcyanoacrylate) core-shell nanoparticles. , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[34] M. Rafiee-Tehrani,et al. Preparation and characterization of insulin nanoparticles using chitosan and its quaternized derivatives. , 2008, Nanomedicine : nanotechnology, biology, and medicine.
[35] Nazma N. Inamdar,et al. Chitosan-modifications and applications: Opportunities galore , 2008 .
[36] Sanjay K. Jain,et al. Target-specific drug release to the colon , 2008, Expert opinion on drug delivery.
[37] T. Coviello,et al. Recent advances and perspectives on coated alginate microspheres for modified drug delivery , 2008, Expert opinion on drug delivery.
[38] S. Nie,et al. Therapeutic Nanoparticles for Drug Delivery in Cancer Types of Nanoparticles Used as Drug Delivery Systems , 2022 .
[39] Shirui Mao,et al. Gene delivery using chitosan, trimethyl chitosan or polyethylenglycol-graft-trimethyl chitosan block copolymers: establishment of structure-activity relationships in vitro. , 2008, Journal of controlled release : official journal of the Controlled Release Society.
[40] R. Khar,et al. Development and characterization of chitosan succinate microspheres for the improved oral bioavailability of insulin. , 2007, Journal of pharmaceutical sciences.
[41] P. Diwan,et al. Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[42] C. Laurencin,et al. Biodegradable polymers as biomaterials , 2007 .
[43] B. Sarmento,et al. Insulin-loaded alginate microspheres for oral delivery – Effect of polysaccharide reinforcement on physicochemical properties and release profile , 2007 .
[44] B. Sarmento,et al. Alginate/Chitosan Nanoparticles are Effective for Oral Insulin Delivery , 2007, Pharmaceutical Research.
[45] Tommasina Coviello,et al. Polysaccharide hydrogels for modified release formulations. , 2007, Journal of controlled release : official journal of the Controlled Release Society.
[46] Y. Sultana,et al. Chitosan Phthalate Microspheres for Oral Delivery of Insulin: Preparation, Characterization, and In Vitro Evaluation , 2007, Drug delivery.
[47] B. Sarmento,et al. Development and characterization of new insulin containing polysaccharide nanoparticles. , 2006, Colloids and surfaces. B, Biointerfaces.
[48] Aldo R Boccaccini,et al. Processing and characterization of porous structures from chitosan and starch for tissue engineering scaffolds. , 2006, Biomacromolecules.
[49] Cui Tang,et al. Chitosan graft copolymer nanoparticles for oral protein drug delivery: preparation and characterization. , 2006, Biomacromolecules.
[50] Gerrit Borchard,et al. Uptake studies in rat Peyer's patches, cytotoxicity and release studies of alginate coated chitosan nanoparticles for mucosal vaccination. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[51] Swarnlata Saraf,et al. Nanocarriers: promising vehicle for bioactive drugs. , 2006, Biological & pharmaceutical bulletin.
[52] T. E. Abraham,et al. Polyionic hydrocolloids for the intestinal delivery of protein drugs: alginate and chitosan--a review. , 2006, Journal of controlled release : official journal of the Controlled Release Society.
[53] David J Mooney,et al. Alginate hydrogels as biomaterials. , 2006, Macromolecular bioscience.
[54] M. Rinaudo,et al. Chitin and chitosan: Properties and applications , 2006 .
[55] P. Couvreur,et al. Nanotechnology: Intelligent Design to Treat Complex Disease , 2006, Pharmaceutical Research.
[56] Shizuka Yamada,et al. Chitosan monomer promotes tissue regeneration on dental pulp wounds. , 2006, Journal of biomedical materials research. Part A.
[57] Sanyog Jain,et al. Chitosan nanoparticles encapsulated vesicular systems for oral immunization: preparation, in‐vitro and in‐vivo characterization , 2006, The Journal of pharmacy and pharmacology.
[58] R. Reis,et al. GRAFT COPOLYMERIZED CHITOSAN-PRESENT STATUS AND APPLICATIONS , 2005 .
[59] Nan-jin Zhou,et al. [The role of local immune response in gastric mucosa in the protection induced by Helicobacter pylori vaccine with chitosan as adjuvant]. , 2005, Zhonghua yi xue za zhi.
[60] D. Fischer,et al. Uptake and Transport of PEG-Graft-Trimethyl-Chitosan Copolymer–Insulin Nanocomplexes by Epithelial Cells , 2005, Pharmaceutical Research.
[61] A. Bernkop‐Schnürch,et al. Preparation and in vitro evaluation of thiolated chitosan microparticles , 2005, Journal of microencapsulation.
[62] Hsing-Wen Sung,et al. Preparation of nanoparticles composed of chitosan/poly-gamma-glutamic acid and evaluation of their permeability through Caco-2 cells. , 2005, Biomacromolecules.
[63] Y. Jeong,et al. Drug release from core-shell type nanoparticles of poly(DL-lactide-co-glycolide)-grafted dextran , 2005, Journal of microencapsulation.
[64] A. Domb,et al. Chitosan chemistry and pharmaceutical perspectives. , 2004, Chemical reviews.
[65] Tejraj M Aminabhavi,et al. Recent advances on chitosan-based micro- and nanoparticles in drug delivery. , 2004, Journal of controlled release : official journal of the Controlled Release Society.
[66] K. Leong,et al. The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. , 2004, Biomaterials.
[67] A. Gupta,et al. Hydrogel pullulan nanoparticles encapsulating pBUDLacZ plasmid as an efficient gene delivery carrier. , 2004, Journal of controlled release : official journal of the Controlled Release Society.
[68] S. Xiong,et al. Intranasal delivery of chitosan-DNA vaccine generates mucosal SIgA and anti-CVB3 protection. , 2004, Vaccine.
[69] H E Junginger,et al. Trimethylated chitosan as polymeric absorption enhancer for improved peroral delivery of peptide drugs. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[70] P. Hubert,et al. Hydrophobically modified alginate hydrogels as protein carriers with specific controlled release properties. , 2004, Journal of controlled release : official journal of the Controlled Release Society.
[71] A. Poso,et al. Drug release from starch-acetate microparticles and films with and without incorporated alpha-amylase. , 2004, Biomaterials.
[72] K. Akiyoshi,et al. Single molecular mechanics of a cholesterol-bearing pullulan nanogel at the hydrophobic interfaces. , 2004, Biomaterials.
[73] C. van Nostrum,et al. Biodegradable dextran hydrogels crosslinked by stereocomplex formation for the controlled release of pharmaceutical proteins. , 2004, International journal of pharmaceutics.
[74] A. Bernkop‐Schnürch,et al. Thiolated chitosans: development and in vitro evaluation of a mucoadhesive, permeation enhancing oral drug delivery system. , 2004, Journal of controlled release : official journal of the Controlled Release Society.
[75] J. Mano,et al. Chitosan-Based Particles as Controlled Drug Delivery Systems , 2004, Drug delivery.
[76] M. K. Chourasia,et al. Polysaccharides for Colon Targeted Drug Delivery , 2004, Drug delivery.
[77] A. Bernkop‐Schnürch,et al. Permeation enhancing polymers in oral delivery of hydrophilic macromolecules: thiomer/GSH systems. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[78] M. Lacroix,et al. N-acylated chitosan: hydrophobic matrices for controlled drug release. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[79] J. de Braekeleer,et al. Generation of Toxoplasma gondii GRA1 protein and DNA vaccine loaded chitosan particles: preparation, characterization, and preliminary in vivo studies. , 2003, International journal of pharmaceutics.
[80] Mansoor Amiji,et al. Chitosan-based gastrointestinal delivery systems. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[81] H. Junginger,et al. Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice. , 2003, Vaccine.
[82] Eun Seong Lee,et al. Adriamycin loaded pullulan acetate/sulfonamide conjugate nanoparticles responding to tumor pH: pH-dependent cell interaction, internalization and cytotoxicity in vitro. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[83] A. Bernkop‐Schnürch,et al. In vitro evaluation of polymeric excipients protecting calcitonin against degradation by intestinal serine proteases. , 2003, International journal of pharmaceutics.
[84] Yumin Du,et al. Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles. , 2003, International journal of pharmaceutics.
[85] Tsutomu Suzuki,et al. Chitosan capsules for colon-specific drug delivery: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats. , 2002, Journal of controlled release : official journal of the Controlled Release Society.
[86] G. Hardee,et al. Characterization of alginate/poly-L-lysine particles as antisense oligonucleotide carriers. , 2002, International journal of pharmaceutics.
[87] Kazushi Fujimoto,et al. Hierarchical Self-Assembly of Hydrophobically Modified Pullulan in Water: Gelation by Networks of Nanoparticles , 2002 .
[88] H. Tønnesen,et al. Alginate in Drug Delivery Systems , 2002, Drug development and industrial pharmacy.
[89] H E Junginger,et al. Chitosan for mucosal vaccination. , 2001, Advanced drug delivery reviews.
[90] I. Kwon,et al. Structural characteristics of size-controlled self-aggregates of deoxycholic acid-modified chitosan and their application as a DNA delivery carrier. , 2001, Bioconjugate chemistry.
[91] A. Maitra,et al. Tumour targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier. , 2001, Journal of controlled release : official journal of the Controlled Release Society.
[92] M. Taha,et al. Synthesis of iron-crosslinked chitosan succinate and iron-crosslinked hydroxamated chitosan succinate and their in vitro evaluation as potential matrix materials for oral theophylline sustained-release beads. , 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[93] H E Junginger,et al. Chitosan microparticles for oral vaccination: preparation, characterization and preliminary in vivo uptake studies in murine Peyer's patches. , 2001, Biomaterials.
[94] K. Janes,et al. Polysaccharide colloidal particles as delivery systems for macromolecules. , 2001, Advanced drug delivery reviews.
[95] H E Junginger,et al. In Vivo Uptake of Chitosan Microparticles by Murine Peyer's Patches: Visualization Studies using Confocal Laser Scanning Microscopy and Immunohistochemistry , 2001, Journal of drug targeting.
[96] P. Wertz,et al. Enhancing effect of chitosan on peptide drug delivery across buccal mucosa. , 2000, Biomaterials.
[97] Caldwell,et al. Mucin Adsorption to Hydrophobic Surfaces. , 2000, Journal of colloid and interface science.
[98] C. Sharma,et al. Beta cyclodextrin-insulin-encapsulated chitosan/alginate matrix : Oral delivery system , 2000 .
[99] P. Couvreur,et al. Insulin‐loaded nanocapsules for oral administration: In vitro and in vivo investigation , 2000 .
[100] H. Ichikawa,et al. Chitosan-Gadopentetic Acid Complex Nanoparticles for Gadolinium Neutron-Capture Therapy of Cancer: Preparation by Novel Emulsion-Droplet Coalescence Technique and Characterization , 1999, Pharmaceutical Research.
[101] T. Fujinaga,et al. Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs. , 1999, Biomaterials.
[102] L. Yang,et al. A new intragastric delivery system for the treatment of Helicobacter pylori associated gastric ulcer: in vitro evaluation. , 1999, Journal of controlled release : official journal of the Controlled Release Society.
[103] T. Fujita,et al. Colon-specific delivery of R68070, a new thromboxane synthase inhibitor, using chitosan capsules: therapeutic effects against 2,4,6-trinitrobenzene sulfonic acid-induced ulcerative colitis in rats. , 1999, Life sciences.
[104] R. Mumper,et al. Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery. , 1998, Journal of controlled release : official journal of the Controlled Release Society.
[105] P Buri,et al. Chitosan: a unique polysaccharide for drug delivery. , 1998, Drug development and industrial pharmacy.
[106] L. Illum,et al. Chitosan and its use as a pharmaceutical excipient. , 1998, Pharmaceutical research.
[107] S. W. Kim,et al. Self-assembled hydrogel nanoparticle of cholesterol-bearing pullulan as a carrier of protein drugs: complexation and stabilization of insulin. , 1998, Journal of controlled release : official journal of the Controlled Release Society.
[108] Wayne R. Gombotz,et al. Protein release from alginate matrices. , 1998, Advanced drug delivery reviews.
[109] W. Hennink,et al. Dextran hydrogels for the controlled release of proteins , 1997 .
[110] S. Tokura,et al. Effects of chitin and its derivatives on the proliferation and cytokine production of fibroblasts in vitro. , 1997, Biomaterials.
[111] H. Junginger,et al. Mucoadhesive polymers in peroral peptide drug delivery. IV. Polycarbophil and chitosan are potent enhancers of peptide transport across intestinal mucosae in vitro , 1997 .
[112] T. Maruyama,et al. Chitosan capsules for colon-specific drug delivery: improvement of insulin absorption from the rat colon. , 1996, Journal of pharmaceutical sciences.
[113] Mansoor M. Amiji,et al. Preparation and Characterization of Freeze-dried Chitosan-Poly(Ethylene Oxide) Hydrogels for Site-Specific Antibiotic Delivery in the Stomach , 1996, Pharmaceutical Research.
[114] H. Brøndsted,et al. Dextran hydrogels for colon-specific drug delivery. V. Degradation in human intestinal incubation models , 1995 .
[115] E. Schacht,et al. Alginates as drug carriers: covalent attachment of alginates to therapeutic agents containing primary amine groups , 1995 .
[116] L. Rubin,et al. Evidence that tyrosine phosphorylation may increase tight junction permeability. , 1995, Journal of cell science.
[117] Takehiro Nishikawa,et al. Supramolecular Assembly between Nanoparticles of Hydrophobized Polysaccharide and Soluble Protein Complexation between the Self-Aggregate of Cholesterol-Bearing Pullulan and .alpha.-Chymotrypsin , 1994 .
[118] Lisbeth Illum,et al. Effect of Chitosan on the Permeability of Monolayers of Intestinal Epithelial Cells (Caco-2) , 1994, Pharmaceutical Research.
[119] Toshiharu Horie,et al. Enhancement of Colonic Drug Absorption by the Transcellular Permeation Route , 1988, Pharmaceutical Research.
[120] T. Nagai,et al. Directly compressed tablets containing chitin or chitosan in addition to lactose or potato starch. , 1982, Chemical & pharmaceutical bulletin.
[121] M. Rekha,et al. Hemocompatible pullulan-polyethyleneimine conjugates for liver cell gene delivery: In vitro evaluation of cellular uptake, intracellular trafficking and transfection efficiency. , 2011, Acta biomaterialia.
[122] Gerrit Borchard,et al. Progress in chitosan-based vaccine delivery systems , 2010 .
[123] Yu-Hsin Lin,et al. Preparation and characterization of nanoparticles shelled with chitosan for oral insulin delivery. , 2007, Biomacromolecules.
[124] S. Rossi,et al. Nanoparticles based on N-trimethylchitosan: evaluation of absorption properties using in vitro (Caco-2 cells) and ex vivo (excised rat jejunum) models. , 2007, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
[125] V. Labhasetwar,et al. Nanosystems in Drug Targeting: Opportunities and Challenges , 2005 .
[126] G. Barratt,et al. Colloidal drug carriers: achievements and perspectives , 2003, Cellular and Molecular Life Sciences CMLS.
[127] C. Sharma,et al. Lipoinsulin encapsulated alginate-chitosan capsules: intestinal delivery in diabetic rats , 2000, Journal of microencapsulation.
[128] G. Mahrous,et al. Preparation and evaluation of sustained release cross-linked chitosan microspheres containing phenobarbitone. , 1998, Journal of microencapsulation.
[129] Y. Shigemasa,et al. Applications of chitin and chitosan for biomaterials. , 1996, Biotechnology & genetic engineering reviews.
[130] A. Moes. Gastroretentive dosage forms. , 1993, Critical reviews in therapeutic drug carrier systems.
[131] J. Mano,et al. hitosan derivatives obtained by chemical modifications for biomedical nd environmental applications , 2022 .