Expression of endothelial and inducible NOS-isoforms is increased in Alzheimer’s disease, in APP23 transgenic mice and after experimental brain lesion in rat: evidence for an induction by amyloid pathology

[1]  J. Rafols,et al.  Expression of the inducible nitric oxide synthase in distinct cellular types after traumatic brain injury: an in situ hybridization and immunocytochemical study , 2000, Acta Neuropathologica.

[2]  M. Staufenbiel,et al.  Transgenic Mouse Models of Alzheimer's Disease , 2000, Annals of the New York Academy of Sciences.

[3]  K. Hensley,et al.  Reactive oxygen species, cell signaling, and cell injury. , 2000, Free radical biology & medicine.

[4]  M. Takiguchi,et al.  Induction of Endothelial Nitric-oxide Synthase in Rat Brain Astrocytes by Systemic Lipopolysaccharide Treatment* , 2000, The Journal of Biological Chemistry.

[5]  L. V. Van Eldik,et al.  β-Amyloid Stimulation of Inducible Nitric-oxide Synthase in Astrocytes Is Interleukin-1β- and Tumor Necrosis Factor-α (TNFα)-dependent, and Involves a TNFα Receptor-associated Factor- and NFκB-inducing Kinase-dependent Signaling Mechanism* , 2000, The Journal of Biological Chemistry.

[6]  J. Wands,et al.  Aberrant expression of nitric oxide synthase III in Alzheimer’s disease: relevance to cerebral vasculopathy and neurodegeneration , 2000, Neurobiology of Aging.

[7]  H. Gertz,et al.  Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a , 2000, Brain Research.

[8]  D. Bredt.  Endogenous nitric oxide synthesis: biological functions and pathophysiology. , 1999, Free radical research.

[9]  Ted M. Dawson,et al.  Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease , 1999, Nature Medicine.

[10]  R. Floyd.  Antioxidants, oxidative stress, and degenerative neurological disorders. , 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[11]  G. Gibson,et al.  Oxidative stress is associated with region-specific neuronal death during thiamine deficiency. , 1999, Journal of neuropathology and experimental neurology.

[12]  P. Kaufman.  Nitric-oxide synthase and neurodegeneration/neuroprotection. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[13]  V. Casagrande,et al.  Endothelial nitric oxide synthetase (eNOS) in astrocytes: Another source of nitric oxide in neocortex , 1999, Glia.

[14]  U. Gärtner,et al.  Elevated expression of p21ras is an early event in Alzheimer's disease and precedes neurofibrillary degeneration , 1999, Neuroscience.

[15]  S. Moncada.  Nitric oxide: discovery and impact on clinical medicine , 1999, Journal of the Royal Society of Medicine.

[16]  D. Yew,et al.  Nitric oxide synthase neurons in different areas of normal aged and Alzheimer's brains , 1999, Neuroscience.

[17]  J. Wands,et al.  Neuritic sprouting with aberrant expression of the nitric oxide synthase III gene in neurodegenerative diseases , 1999, Journal of the Neurological Sciences.

[18]  M. Johnstone,et al.  A central role for astrocytes in the inflammatory response to β-amyloid; chemokines, cytokines and reactive oxygen species are produced , 1999, Journal of Neuroimmunology.

[19]  F. Muramori,et al.  A quantitative study of neurofibrillary tangles, senile plaques and astrocytes in the hippocampal subdivisions and entorhinal cortex in Alzheimer's disease, normal controls and non‐Alzheimer neuropsychiatric diseases , 1998, Psychiatry and clinical neurosciences.

[20]  T. Dawson,et al.  Nitric oxide mediates N-methyl-D-aspartate receptor-induced activation of p21ras. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[21]  B. Chromy,et al.  Amyloid-β peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release , 1998, Brain Research.

[22]  E. Masliah,et al.  nNOS Expressing Neurons in the Entorhinal Cortex and Hippocampus Are Affected in Patients with Alzheimer's Disease , 1998, Experimental Neurology.

[23]  B. Sommer,et al.  Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[24]  K. Zilles,et al.  Transient changes in the presence of nitric oxide synthases and nitrotyrosine immunoreactivity after focal cortical lesions , 1997, Neuroscience.

[25]  T. Arendt,et al.  Co‐expression of APP with cNOS but not iNOS after cortical injury in rat , 1997, Neuroreport.

[26]  H. Lüth.  Ultrastructural demonstration of constitutive nitric oxide synthase (cNOS) in neocortical glial cells and glial perisynaptic sheaths. , 1997, Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.

[27]  M. N. Wallace,et al.  Nitric Oxide Synthase in Reactive Astrocytes Adjacent to β-Amyloid Plaques , 1997, Experimental Neurology.

[28]  Axel Gödecke,et al.  Endothelial nitric oxide synthase and LTP , 1997, Nature.

[29]  P. Slater,et al.  Localization of neuronal and endothelial nitric oxide synthase isoforms in human hippocampus , 1997, Neuroscience.

[30]  M. Sporn,et al.  Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease , 1996, The Journal of experimental medicine.

[31]  M. Barna,et al.  Activation of type III nitric oxide synthase in astrocytes following a neurotropic viral infection. , 1996, Virology.

[32]  P. Emson,et al.  Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains. , 1996, Brain research. Molecular brain research.

[33]  F. Rossi,et al.  Synergistic Induction of Nitric Oxide by β-Amyloid and Cytokines in Astrocytes , 1996 .

[34]  C. Brosnan,et al.  Cytokine Regulation of iNOS Expression in Human Glial Cells , 1996, Methods.

[35]  D. Perl,et al.  Evidence of neuronal oxidative damage in Alzheimer's disease. , 1996, The American journal of pathology.

[36]  Y. Agid,et al.  Nitric oxide synthase and neuronal vulnerability in parkinson's disease , 1996, Neuroscience.

[37]  Simon C Watkins,et al.  Inducible Nitric Oxide Synthase Expression in Cerebrovascular Smooth Muscle and Neutrophils after Traumatic Brain Injury in Immature Rats1 , 1996, Pediatric Research.

[38]  Paul Leonard Gabbott,et al.  Localisation of NADPH diaphorase activity and NOS immunoreactivity in astroglia in normal adult rat brain , 1996, Brain Research.

[39]  M. Bukrinsky,et al.  Cytokine‐stimulated astrocytes damage human neurons via a nitric oxide mechanism , 1996, Glia.

[40]  J. Westman,et al.  Involvement of nitric oxide in acute spinal cord injury: an immunocytochemical study using light and electron microscopy in the rat , 1996, Neuroscience Research.

[41]  D. Harrison,et al.  REGULATION OF EXPRESSION OF THE ENDOTHELIAL CELL NITRIC OXIDE SYNTHASE , 1996, Clinical and experimental pharmacology & physiology.

[42]  O. Bagasra,et al.  Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[43]  J. Schulz,et al.  Role of nitric oxide in neurodegenerative diseases. , 1995, Current opinion in neurology.

[44]  D. Dickson,et al.  Interleukin-1, Nitric Oxide and Reactive Astrocytes , 1995, Brain, Behavior, and Immunity.

[45]  U. Förstermann,et al.  Isoforms of nitric oxide synthase. Properties, cellular distribution and expressional control. , 1995, Biochemical pharmacology.

[46]  T. Arendt,et al.  Increased expression and subcellular translocation of the mitogen activated protein kinase kinase and mitogen-activated protein kinase in Alzheimer's disease , 1995, Neuroscience.

[47]  R. Heumann,et al.  Induction of p21ras in Alzheimer pathology. , 1995, Neuroreport.

[48]  G. White,et al.  Benzodiazepine site inverse agonists can selectively inhibit subtypes of the GABAA receptor. , 1995, Neuroreport.

[49]  M. Ross,et al.  Inducible Nitric Oxide Synthase Gene Expression in Brain following Cerebral Ischemia , 1995, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[50]  Brian J Cummings,et al.  Early association of reactive astrocytes with senile plaques in Alzheimer's disease , 1995, Experimental Neurology.

[51]  S. F. Pearce,et al.  Nitric Oxide-stimulated Guanine Nucleotide Exchange on p21ras(*) , 1995, The Journal of Biological Chemistry.

[52]  B. Mayer,et al.  Morphological analyses of NADPH-diaphorase/nitric oxide synthase positive structures in human visual cortex , 1994, Journal of neurocytology.

[53]  J. Pollock,et al.  Nitric oxide synthase activity is elevated in brain microvessels in Alzheimer's disease. , 1994, Biochemical and biophysical research communications.

[54]  Brian J Cummings,et al.  β-Amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease , 1994, Neuroscience.

[55]  S. Murphy,et al.  Duration of expression of inducible nitric oxide synthase in glial cells , 1994, Journal of neuroscience research.

[56]  S. Snyder,et al.  Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury , 1994, Neuroscience.

[57]  L. Ignarro,et al.  Nitric oxide as a potential pathological mechanism in demyelination: Its differential effects on primary glial cellsin vitro , 1994, Neuroscience.

[58]  K. Maiese,et al.  Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia , 1994, Brain Research.

[59]  S H Snyder,et al.  Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[60]  M. N. Wallace,et al.  NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase , 1994, Neuroscience.

[61]  I. Divac,et al.  Bilateral induction of NADPH-diaphorase activity in neocortical and hippocampal neurons by unilateral injury , 1993, Brain Research.

[62]  E. El-Fakahany,et al.  beta-Amyloid 25-35 activates nitric oxide synthase in a neuronal clone. , 1993, Neuroreport.

[63]  R. Frederickson.  Astroglia in Alzheimer's disease , 1992, Neurobiology of Aging.

[64]  P. Davies,et al.  Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau. , 1992, The Journal of biological chemistry.

[65]  Z. Khachaturian.  Diagnosis of Alzheimer's disease. , 1985, Archives of neurology.

[66]  Y. Agid,et al.  Brain glutamate decarboxylase in Parkinson's disease with particular reference to a premortem severity index. , 1985, Brain : a journal of neurology.

[67]  J. Rogin,et al.  Peripheral sensory neuropathy and cisplatin chemotherapy , 1984, Neurology.

[68]  M. Folstein,et al.  Clinical diagnosis of Alzheimer's disease , 1984, Neurology.

[69]  S. Murphy.  Production of nitric oxide by glial cells: Regulation and potential roles in the CNS , 2000, Glia.

[70]  P. Kelly,et al.  Transgenic Approaches to Model Alzheimer's Disease , 2000, Reviews in the neurosciences.

[71]  H. Akiyama,et al.  Cell mediators of inflammation in the Alzheimer disease brain. , 2000, Alzheimer disease and associated disorders.

[72]  A. van Dam,et al.  Production, regulation and role of nitric oxide in glial cells. , 1998, Mediators of inflammation.

[73]  T. Dawson,et al.  Regulation of neuronal nitric oxide synthase and identification of novel nitric oxide signaling pathways. , 1998, Progress in brain research.

[74]  T. Arendt,et al.  Nitric oxide and Alzheimer's disease. , 1998, Journal fur Hirnforschung.

[75]  T. Dawson,et al.  Nitric oxide in neurodegeneration. , 1998, Progress in brain research.

[76]  S. M. de la Monte,et al.  Aberrant expression of the constitutive endothelial nitric oxide synthase gene in Alzheimer disease. , 1997, Molecular and chemical neuropathology.

[77]  G. Nisticó,et al.  Release of nitric oxide from astroglial cells: a key mechanism in neuroimmune disorders. , 1995, Advances in neuroimmunology.

[78]  F. Gallyas,et al.  Silver staining of Alzheimer's neurofibrillary changes by means of physical development. , 1971, Acta morphologica Academiae Scientiarum Hungaricae.