Perfluorocarbon‐Loaded and Redox‐Activatable Photosensitizing Agent with Oxygen Supply for Enhancement of Fluorescence/Photoacoustic Imaging Guided Tumor Photodynamic Therapy

[1]  Andrew Marshall,et al.  Comparison of Photoacoustically Derived Hemoglobin and Oxygenation Measurements with Contrast-Enhanced Ultrasound Estimated Vascularity and Immunohistochemical Staining in a Breast Cancer Model , 2015, Ultrasonic imaging.

[2]  R. Dasgupta,et al.  Effects of acute hypoxic exposure on oxygen affinity of human red blood cells. , 2017, Applied optics.

[3]  Thomas Kissel,et al.  In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. , 2003, Biomaterials.

[4]  J. Briceño,et al.  Perfluorocarbon-based oxygen carriers: review of products and trials. , 2010, Artificial organs.

[5]  Lihong V. Wang,et al.  Photoacoustic Tomography: In Vivo Imaging from Organelles to Organs , 2012, Science.

[6]  K. Na,et al.  Self-assembled chlorin e6 conjugated chondroitin sulfate nanodrug for photodynamic therapy. , 2011, Biomacromolecules.

[7]  Lihong V. Wang,et al.  Photoacoustic imaging in biomedicine , 2006 .

[8]  Peng Liu,et al.  Photosensitizer-conjugated redox-responsive dextran theranostic nanoparticles for near-infrared cancer imaging and photodynamic therapy , 2014 .

[9]  C. Jaffe,et al.  Metabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty. , 1990, The American journal of cardiology.

[10]  Kai Yang,et al.  Covalent Organic Polymers Based on Fluorinated Porphyrin as Oxygen Nanoshuttles for Tumor Hypoxia Relief and Enhanced Photodynamic Therapy , 2018, Advanced Functional Materials.

[11]  Adrian L. Harris,et al.  Hypoxia — a key regulatory factor in tumour growth , 2002, Nature Reviews Cancer.

[12]  T. Dougherty,et al.  HOW DOES PHOTODYNAMIC THERAPY WORK? , 1992, Photochemistry and photobiology.

[13]  Guoqiang Yu,et al.  Tumor vascular microenvironment determines responsiveness to photodynamic therapy. , 2012, Cancer research.

[14]  Jinhui Wu,et al.  Oxygen self-enriched nanoparticles functionalized with erythrocyte membranes for long circulation and enhanced phototherapy. , 2017, Acta biomaterialia.

[15]  Jarod C Finlay,et al.  The role of photodynamic therapy (PDT) physics. , 2008, Medical physics.

[16]  W. Dietel,et al.  Internalization of Aggregated Photosensitizers by Tumor Cells: Subcellular Time-resolved Fluorescence Spectroscopy on Derivatives of Pyropheophorbide-a Ethers and Chlorin e6 under Femtosecond One- and Two-photon Excitation¶ , 2002 .

[17]  Chao Wang,et al.  Erythrocyte‐Membrane‐Enveloped Perfluorocarbon as Nanoscale Artificial Red Blood Cells to Relieve Tumor Hypoxia and Enhance Cancer Radiotherapy , 2017, Advanced materials.

[18]  J. Brown,et al.  Exploiting tumour hypoxia in cancer treatment , 2004, Nature Reviews Cancer.

[19]  R. Jain,et al.  Photodynamic therapy for cancer , 2003, Nature Reviews Cancer.

[20]  I. Tannock,et al.  Drug resistance and the solid tumor microenvironment. , 2007, Journal of the National Cancer Institute.

[21]  K. Na,et al.  Acetylated hyaluronic acid/photosensitizer conjugate for the preparation of nanogels with controllable phototoxicity: synthesis, characterization, autophotoquenching properties, and in vitro phototoxicity against HeLa cells. , 2010, Bioconjugate chemistry.

[22]  Shai Ashkenazi,et al.  In vivo photoacoustic lifetime imaging of tumor hypoxia in small animals , 2013, Journal of biomedical optics.

[23]  B W Henderson,et al.  Relationship of tumor hypoxia and response to photodynamic treatment in an experimental mouse tumor. , 1987, Cancer research.

[24]  Kai Yang,et al.  Ultrasound Triggered Tumor Oxygenation with Oxygen-Shuttle Nanoperfluorocarbon to Overcome Hypoxia-Associated Resistance in Cancer Therapies. , 2016, Nano letters.

[25]  Haijun Yu,et al.  Photoactivation switch from type II to type I reactions by electron-rich micelles for improved photodynamic therapy of cancer cells under hypoxia. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[26]  Qi Lei,et al.  ACPI Conjugated Gold Nanorods as Nanoplatform for Dual Image Guided Activatable Photodynamic and Photothermal Combined Therapy In Vivo. , 2017, Small.

[27]  Wei Zheng,et al.  Manganese toxicity upon overexposure , 2004, NMR in biomedicine.

[28]  M. Hashida,et al.  Liver targeting of catalase by cationization for prevention of acute liver failure in mice. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[29]  Martyna Elas,et al.  The role of strong hypoxia in tumors after treatment in the outcome of bacteriochlorin-based photodynamic therapy. , 2014, Free radical biology & medicine.

[30]  D. Cui,et al.  MMP2-Targeting and Redox-Responsive PEGylated Chlorin e6 Nanoparticles for Cancer Near-Infrared Imaging and Photodynamic Therapy. , 2016, ACS applied materials & interfaces.

[31]  Yi Chen,et al.  GE11 peptide modified and reduction-responsive hyaluronic acid-based nanoparticles induced higher efficacy of doxorubicin for breast carcinoma therapy , 2016, International journal of nanomedicine.

[32]  Liangzhu Feng,et al.  Drug‐induced co‐assembly of albumin/catalase as smart nano‐theranostics for deep intra‐tumoral penetration, hypoxia relieve, and synergistic combination therapy , 2017, Journal of controlled release : official journal of the Controlled Release Society.

[33]  V. S. Bagnato,et al.  Photodynamic therapy induced vascular damage: an overview of experimental PDT , 2013 .

[34]  M. Verity.  Manganese neurotoxicity: a mechanistic hypothesis. , 1999, Neurotoxicology.

[35]  Zhuang Liu,et al.  Modulation of Hypoxia in Solid Tumor Microenvironment with MnO2 Nanoparticles to Enhance Photodynamic Therapy , 2016 .

[36]  R. Gurny,et al.  State of the art in the delivery of photosensitizers for photodynamic therapy. , 2002, Journal of photochemistry and photobiology. B, Biology.

[37]  W. Hennink,et al.  Reduction-sensitive polymers and bioconjugates for biomedical applications. , 2009, Biomaterials.

[38]  K. Soo,et al.  Nanoparticles in photodynamic therapy. , 2015, Chemical reviews.

[39]  David Kessel,et al.  Photodynamic therapy of cancer: An update , 2011, CA: a cancer journal for clinicians.

[40]  Mengyao Wang,et al.  Oxygen-generating Hybrid Polymeric Nanoparticles with Encapsulated Doxorubicin and Chlorin e6 for Trimodal Imaging-Guided Combined Chemo-Photodynamic Therapy , 2018, Theranostics.

[41]  Dehong Hu,et al.  Smart hyaluronidase-actived theranostic micelles for dual-modal imaging guided photodynamic therapy. , 2016, Biomaterials.

[42]  K. Gunter,et al.  Manganese and calcium transport in mitochondria: implications for manganese toxicity. , 1999, Neurotoxicology.

[43]  E. Akkaya,et al.  Activatable Photosensitizers: Agents for Selective Photodynamic Therapy , 2017 .

[44]  J Moan,et al.  Uptake of the components of hematoporphyrin derivative by cells and tumours. , 1983, Cancer letters.

[45]  Guoyao Wu,et al.  Glutathione metabolism and its implications for health. , 2004, The Journal of nutrition.

[46]  K. Lowe.  Perfluorinated blood substitutes and artificial oxygen carriers. , 1999, Blood reviews.

[47]  P. Rehak,et al.  Combined photodynamic therapy and hyperbaric oxygenation in carcinoma of the esophagus and the esophago-gastric junction. , 2000, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[48]  Saehun Mun,et al.  Photosensitizer-conjugated polymeric nanoparticles for redox-responsive fluorescence imaging and photodynamic therapy. , 2013, Journal of materials chemistry. B.

[49]  Zibo Li,et al.  Red Blood Cell‐Facilitated Photodynamic Therapy for Cancer Treatment , 2016, Advanced functional materials.

[50]  H. Aebi,et al.  Catalase in vitro. , 1984, Methods in enzymology.

[51]  S. Cole,et al.  The catalase—peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis , 1992, Nature.

[52]  A. Habeeb.  A sensitive method for localization of disulfide containing peptides in column effluents. , 1973, Analytical biochemistry.