Ginkgolide B attenuates cerebral ischemia-reperfusion injury via inhibition of ferroptosis through disrupting NCOA4-FTH1 interaction.

[1]  Jisu Kim,et al.  Selective ischemic-hemisphere targeting Ginkgolide B liposomes with improved solubility and therapeutic efficacy for cerebral ischemia-reperfusion injury , 2023, Asian journal of pharmaceutical sciences.

[2]  M. C. Faniello,et al.  Ferritin Heavy Chain Binds Peroxiredoxin 6 and Inhibits Cell Proliferation and Migration , 2022, International journal of molecular sciences.

[3]  Liuting Zeng,et al.  A systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury , 2022, Frontiers in Immunology.

[4]  J. Gwathmey,et al.  Molecular Mechanisms of Ferroptosis and Relevance to Cardiovascular Disease , 2022, Cells.

[5]  Ming Li,et al.  Baicalein ameliorates cerebral ischemia-reperfusion injury by inhibiting ferroptosis via regulating GPX4/ACSL4/ACSL3 axis. , 2022, Chemico-biological interactions.

[6]  J. Fandrey,et al.  Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction , 2022, Cell Death & Disease.

[7]  V. Dalal,et al.  In-silico functional and structural annotation of hypothetical protein from Klebsiella pneumonia: A potential drug target. , 2022, Journal of molecular graphics & modelling.

[8]  X. Xiong,et al.  Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cerebral Ischemia/Reperfusion Injury , 2022, Frontiers in Cellular Neuroscience.

[9]  L. Kong,et al.  Ginkgolide B Targets and Inhibits Creatine Kinase B to Regulate the CCT/TRiC-SK1 Axis and Exerts Pro-Angiogenic Activity in Middle Cerebral Artery Occlusion Mice. , 2022, Pharmacological research.

[10]  Y. Wang,et al.  Ligustilide ameliorates hippocampal neuronal injury after cerebral ischemia reperfusion through activating PINK1/Parkin-dependent mitophagy. , 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[11]  S. R. Pathak,et al.  Structural-based virtual screening and identification of novel potent antimicrobial compounds against YsxC of Staphylococcus aureus , 2022, Journal of Molecular Structure.

[12]  Ning Liu,et al.  Nuclear receptor coactivator 4-mediated ferritinophagy contributes to cerebral ischemia-induced ferroptosis in ischemic stroke. , 2021, Pharmacological research.

[13]  S. Baek,et al.  Histochrome Attenuates Myocardial Ischemia-Reperfusion Injury by Inhibiting Ferroptosis-Induced Cardiomyocyte Death , 2021, Antioxidants.

[14]  Weizu Li,et al.  Ginsenoside Rg1 attenuates cerebral ischemia-reperfusion injury due to inhibition of NOX2-mediated calcium homeostasis dysregulation in mice , 2021, Journal of ginseng research.

[15]  Yitao Wang,et al.  Notoginsenoside R1 intervenes degradation and redistribution of tight junctions to ameliorate blood-brain barrier permeability by Caveolin-1/MMP2/9 pathway after acute ischemic stroke. , 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[16]  V. Dalal,et al.  Identification of potential inhibitors for LLM of Staphylococcus aureus: structure-based pharmacophore modeling, molecular dynamics, and binding free energy studies , 2021, Journal of biomolecular structure & dynamics.

[17]  Qiong Gu,et al.  Inhibiting Ferroptosis through Disrupting the NCOA4–FTH1 Interaction: A New Mechanism of Action , 2021, ACS central science.

[18]  Honglian Shi,et al.  Mitochondrial ferritin attenuates cerebral ischaemia/reperfusion injury by inhibiting ferroptosis , 2021, Cell Death & Disease.

[19]  E. Latz,et al.  Necroptosis, pyroptosis and apoptosis: an intricate game of cell death , 2021, Cellular & Molecular Immunology.

[20]  B. Stockwell,et al.  Ferroptosis: mechanisms, biology and role in disease , 2021, Nature Reviews Molecular Cell Biology.

[21]  Yuanchen Cui,et al.  ACSL4 exacerbates ischemic stroke by promoting ferroptosis-induced brain injury and neuroinflammation , 2021, Brain, Behavior, and Immunity.

[22]  G. Stoll,et al.  The NLRP3 inflammasome drives inflammation in ischemia/reperfusion injury after transient middle cerebral artery occlusion in mice , 2020, Brain, Behavior, and Immunity.

[23]  G. Kroemer,et al.  Ferroptosis: molecular mechanisms and health implications , 2020, Cell Research.

[24]  X. Shan,et al.  Study on the attenuated effect of Ginkgolide B on ferroptosis in high fat diet induced nonalcoholic fatty liver disease. , 2020, Toxicology.

[25]  Zengqiang Yuan,et al.  HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway , 2020, Theranostics.

[26]  Stephen A. Sastra,et al.  Cysteine depletion induces pancreatic tumor ferroptosis in mice , 2020, Science.

[27]  J. Simard,et al.  Emerging Pharmacological Treatments for Cerebral Edema: Evidence from Clinical Studies. , 2020, Annual review of pharmacology and toxicology.

[28]  Yanlin Wang,et al.  Neuroprotective effects of irisin against cerebral ischemia/ reperfusion injury via Notch signaling pathway. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[29]  W. Guo,et al.  Pterostilbene Attenuates Astrocytic Inflammation and Neuronal Oxidative Injury After Ischemia-Reperfusion by Inhibiting NF-κB Phosphorylation , 2019, Front. Immunol..

[30]  Zhenzhong Wang,et al.  Antioxidant effects of ginkgolides and bilobalide against cerebral ischemia injury by activating the Akt/Nrf2 pathway in vitro and in vivo , 2019, Cell Stress and Chaperones.

[31]  Donna D. Zhang,et al.  NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis , 2019, Redox biology.

[32]  Shuai Jiang,et al.  AMPK: Potential Therapeutic Target for Ischemic Stroke , 2018, Theranostics.

[33]  M. Fornage,et al.  Heart Disease and Stroke Statistics—2017 Update: A Report From the American Heart Association , 2017, Circulation.

[34]  C. Iadecola,et al.  Inflammation and Stroke: An Overview , 2016, Neurotherapeutics.

[35]  Q. Pan,et al.  Ferroptosis is an autophagic cell death process , 2016, Cell Research.

[36]  S. Gygi,et al.  Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy , 2014, Nature.

[37]  X. Dong,et al.  Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway. , 2011, Journal of ethnopharmacology.

[38]  P. Pévet,et al.  Activation of glycine receptor phase‐shifts the circadian rhythm in neuronal activity in the mouse suprachiasmatic nucleus , 2011, The Journal of physiology.

[39]  Wei Liu,et al.  Inhibitory effect of melatonin on lung oxidative stress induced by respiratory syncytial virus infection in mice , 2010, Journal of pineal research.

[40]  Yunman Li,et al.  Blood brain barrier permeability and therapeutic time window of Ginkgolide B in ischemia-reperfusion injury. , 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[41]  G. Allais,et al.  Efficacy of Ginkgolide B in the prophylaxis of migraine with aura , 2009, Neurological Sciences.

[42]  K. Nakanishi,et al.  Efficient extraction of ginkgolides and bilobalide from Ginkgo biloba leaves. , 2002, Journal of natural products.

[43]  Paul F. Smith,et al.  The CNS effects of Ginkgo biloba extracts and ginkgolide B , 2002, Progress in Neurobiology.

[44]  B. Diamond,et al.  Ginkgo biloba extract: mechanisms and clinical indications. , 2000, Archives of physical medicine and rehabilitation.

[45]  R. Paczynski,et al.  Automated measurement of infarct size with scanned images of triphenyltetrazolium chloride-stained rat brains. , 1996, Stroke.

[46]  P. Braquet,et al.  Recent progress in ginkgolide research , 1991, Medicinal research reviews.

[47]  P. Weinstein,et al.  Reversible middle cerebral artery occlusion without craniectomy in rats. , 1989, Stroke.