Gene clusters and polycistronic transcription in eukaryotes

Sometimes genes are arranged nonrandomly on the chromosomes of eukaryotes. This review considers instances of gene clusters in which two genes or more are expressed from a single promoter. This includes cases in which a polycistronic pre‐mRNA is processed to make monocistronic mRNAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants. BioEssays 20:480–487, 1998. © 1998 John Wiley & Sons, Inc.

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