Toll-like Receptor 5 Activation by the CagY Repeat Domains of Helicobacter pylori.

[1]  M. Vieth,et al.  T4SS-dependent TLR5 activation by Helicobacter pylori infection , 2019, Nature Communications.

[2]  T. Meyer,et al.  ADP heptose, a novel pathogen-associated molecular pattern identified in Helicobacter pylori , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[3]  A. Frick-Cheng,et al.  Structure of the Helicobacter pylori Cag type IV secretion system , 2019, eLife.

[4]  D. Morgan,et al.  α-Difluoromethylornithine reduces gastric carcinogenesis by causing mutations in Helicobacter pylori cagY , 2019, Proceedings of the National Academy of Sciences.

[5]  L. Itzhaki,et al.  The tetratricopeptide-repeat motif is a versatile platform that enables diverse modes of molecular recognition. , 2019, Current opinion in structural biology.

[6]  S. Mallal,et al.  Helicobacter pylori genetic diversification in the Mongolian gerbil model , 2018, PeerJ.

[7]  Gabriel Waksman,et al.  Type IV secretion in Gram‐negative and Gram‐positive bacteria , 2018, Current Topics in Microbiology and Immunology.

[8]  K. Ottemann,et al.  NLRP3 Controls the Development of Gastrointestinal CD11b+ Dendritic Cells in the Steady State and during Chronic Bacterial Infection. , 2017, Cell reports.

[9]  J. Takagi,et al.  Molecular dissection of protein–protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system , 2017, The FEBS journal.

[10]  S. Wessler,et al.  Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery. , 2017, Cell host & microbe.

[11]  G. Jensen,et al.  In Vivo Structures of the Helicobacter pylori cag Type IV Secretion System , 2017, bioRxiv.

[12]  R. Jerala,et al.  The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5 , 2017, PLoS pathogens.

[13]  O. Sokolova,et al.  Helicobacter pylori: A Paradigm Pathogen for Subverting Host Cell Signal Transmission. , 2017, Trends in microbiology.

[14]  Andrei N Lupas,et al.  Coiled Coils - A Model System for the 21st Century. , 2017, Trends in biochemical sciences.

[15]  Sung-il Yoon,et al.  A conserved TLR5 binding and activation hot spot on flagellin , 2017, Scientific Reports.

[16]  Patrick Olbermann,et al.  Systematic site-directed mutagenesis of the Helicobacter pylori CagL protein of the Cag type IV secretion system identifies novel functional domains , 2016, Scientific Reports.

[17]  S. Backert,et al.  Differential Expression of Interleukin 1β During Helicobacter pylori Infection of Toll-like Receptor 2 (TLR2)- and TLR10-Expressing HEK293 Cell Lines. , 2016, The Journal of infectious diseases.

[18]  Peer Bork,et al.  Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees , 2016, Nucleic Acids Res..

[19]  Eric P. Skaar,et al.  Pathogenic Helicobacter pylori Strains Translocate DNA and Activate TLR9 via the Cancer-Associated cag Type IV Secretion System , 2016, Oncogene.

[20]  M. Blaser,et al.  Molecular and Structural Analysis of the Helicobacter pylori cag Type IV Secretion System Core Complex , 2016, mBio.

[21]  S. Backert,et al.  Helicobacter urease-induced activation of the TLR2/NLRP3/IL-18 axis protects against asthma. , 2015, The Journal of clinical investigation.

[22]  D. Graham,et al.  Toll-like Receptor 10 in Helicobacter pylori Infection. , 2015, The Journal of infectious diseases.

[23]  E. El-Omar,et al.  Interplay of the Gastric Pathogen Helicobacter pylori with Toll-Like Receptors , 2015, BioMed research international.

[24]  C. Mathers,et al.  Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012 , 2015, International journal of cancer.

[25]  S. Backert,et al.  A helical RGD motif promoting cell adhesion: crystal structures of the Helicobacter pylori type IV secretion system pilus protein CagL. , 2013, Structure.

[26]  G. Núñez,et al.  The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL‐1β production in Helicobacter pylori infected dendritic cells , 2013, European journal of immunology.

[27]  M. Rohde,et al.  Electron Microscopic, Genetic and Protein Expression Analyses of Helicobacter acinonychis Strains from a Bengal Tiger , 2013, PloS one.

[28]  Daniel W. A. Buchan,et al.  Scalable web services for the PSIPRED Protein Analysis Workbench , 2013, Nucleic Acids Res..

[29]  J. Gaddy,et al.  Functional Plasticity in the Type IV Secretion System of Helicobacter pylori , 2013, PLoS pathogens.

[30]  Steffen Backert,et al.  Peptidoglycan maturation enzymes affect flagellar functionality in bacteria , 2012, Molecular microbiology.

[31]  K. Gaus,et al.  Cyclic RGD peptides interfere with binding of the Helicobacter pylori protein CagL to integrins αVβ3 and α5β1 , 2012, Amino Acids.

[32]  M. Rohde,et al.  Live Helicobacter pylori in the root canal of endodontic-infected deciduous teeth , 2012, Journal of Gastroenterology.

[33]  T. Cover,et al.  An RGD Helper Sequence in CagL of Helicobacter pylori Assists in Interactions with Integrins and Injection of CagA , 2012, Front. Cell. Inf. Microbio..

[34]  R. Haas,et al.  CagI Is an Essential Component of the Helicobacter pylori Cag Type IV Secretion System and Forms a Complex with CagL , 2012, PloS one.

[35]  Maxim Teslenko,et al.  MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space , 2012, Systematic biology.

[36]  I. Wilson,et al.  Structural Basis of TLR5-Flagellin Recognition and Signaling , 2012, Science.

[37]  M. Rohde,et al.  Major Host Factors Involved in Epithelial Cell Invasion of Campylobacter jejuni: Role of Fibronectin, Integrin Beta1, FAK, Tiam-1, and DOCK180 in Activating Rho GTPase Rac1 , 2011, Front. Cell. Inf. Microbio..

[38]  S. Wessler,et al.  Serine phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori. , 2011, Cell host & microbe.

[39]  S. Brandt,et al.  Induction of TLR-2 and TLR-5 Expression by Helicobacter pylori Switches cagPAI-Dependent Signalling Leading to the Secretion of IL-8 and TNF-α , 2011, PloS one.

[40]  M. Rohde,et al.  A Small Fibronectin-mimicking Protein from Bacteria Induces Cell Spreading and Focal Adhesion Formation* , 2010, The Journal of Biological Chemistry.

[41]  Richard J. Edwards,et al.  SLiMFinder: a web server to find novel, significantly over-represented, short protein motifs , 2010, Nucleic Acids Res..

[42]  K. Jung,et al.  Helicobacter pylori Type IV Secretion Apparatus Exploits β1 Integrin in a Novel RGD-Independent Manner , 2009, PLoS pathogens.

[43]  Gabriel Waksman,et al.  Structure of the outer membrane complex of a type IV secretion system , 2009, Nature.

[44]  C. Prinz,et al.  Extracellular and intracellular pattern recognition receptors cooperate in the recognition of Helicobacter pylori. , 2009, Gastroenterology.

[45]  B. Beutler,et al.  Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases , 2009, Immunological reviews.

[46]  K. Bunting,et al.  The Highly Repetitive Region of the Helicobacter pylori CagY Protein Comprises Tandem Arrays of an α-Helical Repeat Module , 2008, Journal of molecular biology.

[47]  Roland Hartig,et al.  Helicobacter exploits integrin for type IV secretion and kinase activation , 2007, Nature.

[48]  L. V. van Alphen,et al.  Expression patterns and role of the CadF protein in Campylobacter jejuni and Campylobacter coli. , 2007, FEMS microbiology letters.

[49]  T. Wang,et al.  Inflammation, atrophy, and gastric cancer. , 2007, The Journal of clinical investigation.

[50]  T. Steiner How Flagellin and Toll-Like Receptor 5 Contribute to Enteric Infection , 2006, Infection and Immunity.

[51]  T. Kwok,et al.  Conjugative plasmid DNA transfer in Helicobacter pylori mediated by chromosomally encoded relaxase and TraG-like proteins. , 2005, Microbiology.

[52]  W. Souza,et al.  Improvement on the visualization of cytoskeletal structures of protozoan parasites using high-resolution field emission scanning electron microscopy (FESEM) , 2005, Histochemistry and Cell Biology.

[53]  A. Aderem,et al.  Evasion of Toll-like receptor 5 by flagellated bacteria. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[54]  John Bertin,et al.  Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island , 2004, Nature Immunology.

[55]  A. Iwasaki,et al.  Toll-like receptor control of the adaptive immune responses , 2004, Nature Immunology.

[56]  M. Selbach,et al.  Helicobacter pylori Induces AGS Cell Motility and Elongation via Independent Signaling Pathways , 2004, Infection and Immunity.

[57]  Robert C. Edgar,et al.  MUSCLE: multiple sequence alignment with high accuracy and high throughput. , 2004, Nucleic acids research.

[58]  M. Blaser,et al.  Plasticity of Repetitive DNA Sequences within a Bacterial (Type IV) Secretion System Component , 2003, The Journal of experimental medicine.

[59]  M. Rohde,et al.  A novel sheathed surface organelle of the Helicobacter pylori cag type IV secretion system , 2003, Molecular microbiology.

[60]  T. Meyer,et al.  Specific Entry of Helicobacter pylori into Cultured Gastric Epithelial Cells via a Zipper-Like Mechanism , 2002, Infection and Immunity.

[61]  T. Meyer,et al.  Tyrosine phosphorylation patterns and size modification of the Helicobacter pylori CagA protein after translocation into gastric epithelial cells , 2001, Proteomics.

[62]  Wei Qian,et al.  Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis. , 2000, Molecular biology and evolution.

[63]  S Karlin,et al.  Sequence anomalies in the Cag7 gene of the Helicobacter pylori pathogenicity island. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[64]  A. Lupas Coiled coils: new structures and new functions. , 1996, Trends in biochemical sciences.

[65]  M F Dixon,et al.  Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. , 1996, The American journal of surgical pathology.

[66]  R. Rappuoli,et al.  Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[67]  A. Lupas,et al.  Predicting coiled coils from protein sequences , 1991, Science.

[68]  E. Myers,et al.  Basic local alignment search tool. , 1990, Journal of molecular biology.

[69]  W. Remmele,et al.  [Recommendation for uniform definition of an immunoreactive score (IRS) for immunohistochemical estrogen receptor detection (ER-ICA) in breast cancer tissue]. , 1987, Der Pathologe.

[70]  Kevin K. Chang,et al.  Lauren Histologic Type Is the Most Important Factor Associated With Pattern of Recurrence Following Resection of Gastric Adenocarcinoma , 2018, Annals of surgery.

[71]  T. Stradal,et al.  Large-scale analysis of protein-protein interactions using cellulose-bound peptide arrays. , 2008, Advances in biochemical engineering/biotechnology.

[72]  M. Unemo,et al.  Helicobacter pylori adhesion to carbohydrates. , 2006, Methods in enzymology.

[73]  M. Blaser,et al.  Helicobacter pylori and gastrointestinal tract adenocarcinomas , 2002, Nature Reviews Cancer.