Phosphoprotein enriched in astrocytes (PEA)-15 is a novel regulator of adipose tissue expansion

[1]  C. Kahn,et al.  Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome. , 2019, The Journal of clinical investigation.

[2]  P. Formisano,et al.  Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications , 2019, International journal of molecular sciences.

[3]  Ji-Eun Lee,et al.  Transcriptional and Epigenomic Regulation of Adipogenesis , 2019, Molecular and Cellular Biology.

[4]  P. Scherer,et al.  Adipogenesis and metabolic health , 2019, Nature Reviews Molecular Cell Biology.

[5]  W. Han,et al.  Ablation of Bscl2/seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy , 2019, Disease Models & Mechanisms.

[6]  I. C. Nettore,et al.  High-fat diet unveils an enhancer element at the Ped/Pea-15 gene responsible for epigenetic memory in skeletal muscle. , 2018, Metabolism: clinical and experimental.

[7]  J. Després,et al.  Overview of Epidemiology and Contribution of Obesity and Body Fat Distribution to Cardiovascular Disease: An Update. , 2018, Progress in cardiovascular diseases.

[8]  Amir I. Mina,et al.  Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes , 2018, Molecular metabolism.

[9]  J. Després,et al.  Cardiovascular and Metabolic Heterogeneity of Obesity: Clinical Challenges and Implications for Management. , 2018, Circulation.

[10]  K. Suchacki,et al.  Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease , 2018, Molecular metabolism.

[11]  J. Ramos,et al.  PEA‐15 (Phosphoprotein Enriched in Astrocytes 15) Is a Protective Mediator in the Vasculature and Is Regulated During Neointimal Hyperplasia , 2017, Journal of the American Heart Association.

[12]  F. Schick,et al.  Causes, Characteristics, and Consequences of Metabolically Unhealthy Normal Weight in Humans. , 2017, Cell metabolism.

[13]  P. Whitfield,et al.  Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE−/− mouse model of atherosclerosis with alterations in IL10/AMPKα pathway , 2017, Molecular metabolism.

[14]  Matthew J. Potthoff,et al.  FGF21 Regulates Metabolism Through Adipose-Dependent and -Independent Mechanisms. , 2017, Cell metabolism.

[15]  P. Scherer,et al.  The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis. , 2017, The Journal of clinical investigation.

[16]  J. Tomlinson,et al.  Non-alcoholic fatty liver disease and diabetes , 2016, Metabolism: clinical and experimental.

[17]  S. Blair,et al.  Obesity and Cardiovascular Disease , 2006 .

[18]  T. McLaughlin,et al.  Adipose Cell Size and Regional Fat Deposition as Predictors of Metabolic Response to Overfeeding in Insulin-Resistant and Insulin-Sensitive Humans , 2016, Diabetes.

[19]  Lihua Zhou,et al.  The cell size and distribution of adipocytes from subcutaneous and visceral fat is associated with type 2 diabetes mellitus in humans , 2015, Adipocyte.

[20]  P. Scherer,et al.  The cell biology of fat expansion , 2015, The Journal of cell biology.

[21]  G. Nixon,et al.  Phosphoprotein enriched in astrocytes (PEA)-15: A potential therapeutic target in multiple disease states , 2014, Pharmacology & therapeutics.

[22]  A. Wierzbicki,et al.  Nonalcoholic fatty liver disease and lipids , 2012, Current opinion in lipidology.

[23]  A. Sherman,et al.  The Size of Large Adipose Cells Is a Predictor of Insulin Resistance in First‐Degree Relatives of Type 2 Diabetic Patients , 2012, Obesity.

[24]  E. White,et al.  PEA-15 potentiates H-Ras mediated epithelial cell transformation through Phospholipase D , 2011, Oncogene.

[25]  A. Xu,et al.  Fibroblast Growth Factor 21 Induces Glucose Transporter-1 Expression through Activation of the Serum Response Factor/Ets-Like Protein-1 in Adipocytes* , 2011, The Journal of Biological Chemistry.

[26]  J. Ramos,et al.  A phospholipase Cγ1-activated pathway regulates transcription in human vascular smooth muscle cells. , 2011, Cardiovascular research.

[27]  S. Pastorino,et al.  The death effector domain protein PEA‐15 negatively regulates T‐cell receptor signaling , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[28]  A. Vidal-Puig,et al.  Adipose tissue expandability, lipotoxicity and the Metabolic Syndrome--an allostatic perspective. , 2010, Biochimica et biophysica acta.

[29]  G. Perruolo,et al.  Frontiers: PED/PEA-15, a multifunctional protein controlling cell survival and glucose metabolism. , 2009, American journal of physiology. Endocrinology and metabolism.

[30]  P. Libby,et al.  Obesity, inflammation, and atherosclerosis , 2009, Nature Reviews Cardiology.

[31]  Y. Huang,et al.  Mediator MED23 links insulin signaling to the adipogenesis transcription cascade. , 2009, Developmental cell.

[32]  J. Ramos,et al.  Death Effector Domain-Containing Proteins , 2009, Cellular and Molecular Life Sciences.

[33]  A. Vidal-Puig,et al.  Adipose tissue expandability and the metabolic syndrome , 2007, Genes & Nutrition.

[34]  G. Shulman,et al.  Obesity-associated improvements in metabolic profile through expansion of adipose tissue. , 2007, The Journal of clinical investigation.

[35]  A. Tuzcu,et al.  The correlation between adiposity and adiponectin, tumor necrosis factor α, interleukin-6 and high sensitivity C-reactive protein levels. Is adipocyte size associated with inflammation in adults? , 2007, Journal of endocrinological investigation.

[36]  Herbert Tilg,et al.  Adipocytokines: mediators linking adipose tissue, inflammation and immunity , 2006, Nature Reviews Immunology.

[37]  C. Dani,et al.  The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. , 2005, Diabetes.

[38]  C. Lelliott,et al.  ETO/MTG8 Is an Inhibitor of C/EBPβ Activity and a Regulator of Early Adipogenesis , 2004, Molecular and Cellular Biology.

[39]  G. Troncone,et al.  Overexpression of the ped/pea-15 Gene Causes Diabetes by Impairing Glucose-Stimulated Insulin Secretion in Addition to Insulin Action , 2004, Molecular and Cellular Biology.

[40]  E. Formstecher,et al.  PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase. , 2001, Developmental cell.

[41]  R. Muise-Helmericks,et al.  Signal transduction and the Ets family of transcription factors , 2000, Oncogene.

[42]  P. Arner,et al.  Regional differences in the control of lipolysis in human adipose tissue. , 1979, Metabolism: clinical and experimental.

[43]  J. Ramos.  The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells. , 2008, The international journal of biochemistry & cell biology.

[44]  A. G. Shaper,et al.  Obesity and cardiovascular disease. , 1996, Ciba Foundation symposium.

[45]  K. Johnson.  An Update. , 1984, Journal of food protection.