Management of prenatally diagnosed lung lesions.

Prenatal diagnosis provides insight into the in utero evolution of fetal thoracic lesions such as congenital cystic adenomatoid malformation (CCAM), bronchopulmonary sequestration (BPS), or hybrid lesions. Serial sonographic study of fetuses with thoracic lesions has helped define the natural history of these lesions, determine the pathophysiologic features that affect clinical outcome, and formulate in utero and postnatal management based on prognosis.

[1]  R. Goldstein,et al.  Prenatal steroids for microcystic congenital cystic adenomatoid malformations. , 2010, Journal of pediatric surgery.

[2]  N. Adzick.  Management of fetal lung lesions. , 2003, Clinics in perinatology.

[3]  T. Crombleholme,et al.  Ex utero intrapartum treatment procedure: a peripartum management strategy in particularly challenging cases. , 2009, The Journal of pediatrics.

[4]  A. Leite-Moreira,et al.  Cystic adenomatoid malformations are induced by localized FGF10 overexpression in fetal rat lung. , 2008, American journal of respiratory cell and molecular biology.

[5]  M. Bebbington,et al.  Outcomes after postnatal resection of prenatally diagnosed asymptomatic cystic lung lesions. , 2008, Journal of pediatric surgery.

[6]  M. Bebbington,et al.  Postnatal Chest Wall Deformities after Fetal Thoracoamniotic Shunting for Congenital Cystic Adenomatoid Malformation , 2007, Fetal Diagnosis and Therapy.

[7]  M. Bebbington,et al.  Effect of Maternal Betamethasone Administration on Prenatal Congenital Cystic Adenomatoid Malformation Growth and Fetal Survival , 2007, Fetal Diagnosis and Therapy.

[8]  C. Albanese.  The EXIT Strategy , 2005 .

[9]  T. Crombleholme,et al.  The ex utero intrapartum therapy procedure for high-risk fetal lung lesions. , 2005, Journal of pediatric surgery.

[10]  M. Post,et al.  The Molecular Basis for Abnormal Human Lung Development , 2005, Neonatology.

[11]  J. Whitsett,et al.  Genetic disorders influencing lung formation and function at birth. , 2004, Human molecular genetics.

[12]  J. Rychik,et al.  Acute Cardiovascular Effects of Fetal Surgery in the Human , 2004, Circulation.

[13]  M. King,et al.  Thoracoamniotic Shunts: Fetal Treatment of Pleural Effusions and Congenital Cystic Adenomatoid Malformations , 2004, Fetal Diagnosis and Therapy.

[14]  E. Gilbert-Barness,et al.  Embryo and fetal pathology , 2004 .

[15]  E. Cutz,et al.  Expression of Hoxb-5 during human lung development and in congenital lung malformations. , 2003, Birth defects research. Part A, Clinical and molecular teratology.

[16]  T. Crombleholme,et al.  Cystic adenomatoid malformation volume ratio predicts outcome in prenatally diagnosed cystic adenomatoid malformation of the lung. , 2002, Journal of pediatric surgery.

[17]  J. Stocker.  Congenital pulmonary airway malformation : a new name and expanded classification of congenital cystic adenomatoid malformation of the lung , 2002 .

[18]  F. Askin,et al.  Congenital cystic adenomatoid malformation of the lung (CCAM): evaluation of the cellular components. , 1999, Human pathology.

[19]  T. Crombleholme,et al.  Elevated platelet-derived growth factor-B in congenital cystic adenomatoid malformations requiring fetal resection. , 1999, Journal of pediatric surgery.

[20]  T. Crombleholme,et al.  Fetal lung lesions: management and outcome. , 1998, American journal of obstetrics and gynecology.

[21]  P. Stafford,et al.  Cystic lung lesions with systemic arterial blood supply: a hybrid of congenital cystic adenomatoid malformation and bronchopulmonary sequestration. , 1997, Journal of pediatric surgery.

[22]  J. Whitsett,et al.  Pulmonary malformation in transgenic mice expressing human keratinocyte growth factor in the lung. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[23]  R. Filly,et al.  Fetal surgery for cystic adenomatoid malformation of the lung. , 1993, Journal of pediatric surgery.

[24]  A. Flake,et al.  Fetal Surgery in the Primate III. Maternal Outcome After Fetal Surgery , 1986 .

[25]  R. L. Anderson,et al.  Fetal cystic adenomatoid malformation: prenatal diagnosis and natural history. , 1985, Journal of pediatric surgery.

[26]  S. Sorokin,et al.  The Respiratory System , 1983 .

[27]  R. Goodlin.  Care of the fetus , 1979 .

[28]  R. Gruppo,et al.  Rhabdomyosarcoma of lung arising in congenital cystic adenomatoid malformation , 1977, Cancer.

[29]  R. Drake,et al.  Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum. , 1977, Human pathology.

[30]  J. Kilman,et al.  Pulmonary sequestration. , 1975, The Journal of thoracic and cardiovascular surgery.

[31]  C. Stephanopoulos,et al.  Myxosarcoma Complicating a Cystic Hamartoma of the Lung , 1963, Thorax.