Genome Wide Association Studies

[1]  Christoph Lange,et al.  On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls. , 2010, American journal of human genetics.

[2]  L. Cardon,et al.  Aspects of observing and claiming allele flips in association studies , 2009, Genetic epidemiology.

[3]  Scott T. Weiss,et al.  On the Analysis of Genome-Wide Association Studies in Family-Based Designs: A Universal, Robust Analysis Approach and an Application to Four Genome-Wide Association Studies , 2009, PLoS genetics.

[4]  Juan Pablo Lewinger,et al.  Methodological Issues in Multistage Genome-wide Association Studies. , 2009, Statistical science : a review journal of the Institute of Mathematical Statistics.

[5]  Christoph Lange,et al.  The Role of Family-Based Designs in Genome-Wide Association Studies , 2009, 1010.4629.

[6]  F. Kronenberg,et al.  Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design? , 2009, PLoS genetics.

[7]  Iuliana Ionita-Laza,et al.  On Quality Control Measures in Genome-Wide Association Studies: A Test to Assess the Genotyping Quality of Individual Probands in Family-Based Association Studies and an Application to the HapMap Data , 2009, PLoS genetics.

[8]  Christoph Lange,et al.  Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy–Weinberg equilibrium , 2009, European Journal of Human Genetics.

[9]  B. Browning,et al.  A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals. , 2009, American journal of human genetics.

[10]  Aribert Rothenberger,et al.  Genome‐wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[11]  Christoph Lange,et al.  Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE. , 2008, American journal of human genetics.

[12]  Francis S Collins,et al.  A HapMap harvest of insights into the genetics of common disease. , 2008, The Journal of clinical investigation.

[13]  F. Kronenberg,et al.  On the replication of genetic associations: timing can be everything! , 2008, American journal of human genetics.

[14]  Iuliana Ionita-Laza,et al.  On the analysis of copy‐number variations in genome‐wide association studies: a translation of the family‐based association test , 2008, Genetic epidemiology.

[15]  T. Manolio,et al.  How to Interpret a Genome-wide Association Study Topic Collections , 2022 .

[16]  Zhaohui S. Qin,et al.  A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.

[17]  Michael Inouye,et al.  A genotype calling algorithm for the Illumina BeadArray platform , 2007, Bioinform..

[18]  Iuliana Ionita-Laza,et al.  Genomewide weighted hypothesis testing in family-based association studies, with an application to a 100K scan. , 2007, American journal of human genetics.

[19]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[20]  Qiuying Sha,et al.  Two-stage association tests for genome-wide association studies based on family data with arbitrary family structure , 2007, European Journal of Human Genetics.

[21]  P. Donnelly,et al.  A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.

[22]  P. Donnelly,et al.  Replicating genotype–phenotype associations , 2007, Nature.

[23]  D Y Lin,et al.  The use of inferred haplotypes in downstream analyses. , 2007, American journal of human genetics.

[24]  Eden R Martin,et al.  No gene is an island: the flip-flop phenomenon. , 2007, American journal of human genetics.

[25]  Robert C. Elston,et al.  Adaptive Two-Stage Analysis of Genetic Association in Case-Control Designs , 2007, Human Heredity.

[26]  I. Pe’er,et al.  Optimal two‐stage genotyping designs for genome‐wide association scans , 2006, Genetic epidemiology.

[27]  N. Laird,et al.  Family-based designs in the age of large-scale gene-association studies , 2006, Nature Reviews Genetics.

[28]  F. Hu,et al.  A Common Genetic Variant Is Associated with Adult and Childhood Obesity , 2006, Science.

[29]  G. Abecasis,et al.  Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies , 2006, Nature Genetics.

[30]  Terence P. Speed,et al.  Genome analysis A genotype calling algorithm for affymetrix SNP arrays , 2005 .

[31]  Christoph Lange,et al.  Genomic screening and replication using the same data set in family-based association testing , 2005, Nature Genetics.

[32]  M. Olivier.  A haplotype map of the human genome , 2003, Nature.

[33]  D. Thomas,et al.  Two‐Stage sampling designs for gene association studies , 2004, Genetic epidemiology.

[34]  Toshihiro Tanaka.  The International HapMap Project , 2003, Nature.

[35]  Christoph Lange,et al.  Using the noninformative families in family-based association tests: a powerful new testing strategy. , 2003, American journal of human genetics.

[36]  R. Elston,et al.  Optimal two‐stage genotyping in population‐based association studies , 2003, Genetic epidemiology.

[37]  Christoph Lange,et al.  A multivariate family-based association test using generalized estimating equations: FBAT-GEE. , 2003, Biostatistics.

[38]  Aravinda Chakravarti,et al.  Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test. , 2003, American journal of human genetics.

[39]  J. Ott,et al.  A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. , 2001, American journal of human genetics.

[40]  Jurg Ott,et al.  Assessment and management of single nucleotide polymorphism genotype errors in genetic association analysis. , 2000 .

[41]  Daniel Rabinowitz,et al.  A Unified Approach to Adjusting Association Tests for Population Admixture with Arbitrary Pedigree Structure and Arbitrary Missing Marker Information , 2000, Human Heredity.

[42]  J. Ott,et al.  An analytic solution to single nucleotide polymorphism error-detection rates in nuclear families: implications for study design. , 1999, Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing.

[43]  Xin Xu,et al.  Implementing a unified approach to family‐based tests of association , 2000, Genetic epidemiology.

[44]  W. Ewens,et al.  A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. , 1998, American journal of human genetics.

[45]  J. D. Emerson,et al.  Simple robust procedures for combining risk differences in sets of 2 x 2 tables. , 1996, Statistics in medicine.

[46]  W. R. Rice.  A Consensus Combined P-Value Test and the Family-wide Significance of Component Tests , 1990 .

[47]  N. Laird,et al.  Meta-analysis in clinical trials. , 1986, Controlled clinical trials.