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[1]  H. Weiner,et al.  Oral tolerance , 2011, Immunological reviews.

[2]  Brigitta Stockinger,et al.  T Cell Regulation as a Side Effect of Homeostasis and Competition , 2003, The Journal of experimental medicine.

[3]  K. Wood,et al.  Cutting Edge: CD4+CD25+ Alloantigen-Specific Immunoregulatory Cells That Can Prevent CD8+ T Cell-Mediated Graft Rejection: Implications for Anti-CD154 Immunotherapy1 , 2002, The Journal of Immunology.

[4]  Hugh Auchincloss,et al.  Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model. , 2002, Immunity.

[5]  F. Powrie,et al.  CTLA‐4 expression on antigen‐specific cells but not IL‐10 secretion is required for oral tolerance , 2002, European journal of immunology.

[6]  L. Klein,et al.  Origin of regulatory T cells with known specificity for antigen , 2002, Nature Immunology.

[7]  Ethan M. Shevach,et al.  CD4+CD25+ suppressor T cells: more questions than answers , 2002, Nature Reviews Immunology.

[8]  J. Kehren,et al.  Skin Inflammation During Contact Hypersensitivity Is Mediated by Early Recruitment of CD8+ T Cytotoxic 1 Cells Inducing Keratinocyte Apoptosis1 , 2002, The Journal of Immunology.

[9]  R. Flavell,et al.  Preferential Th1 Immune Response in Invariant Chain-Deficient Mice1 , 2002, The Journal of Immunology.

[10]  M. Papiernik,et al.  Natural CD4 CD25(+) regulatory T cells control the burst of superantigen-induced cytokine production: the role of IL-10. , 2002, International immunology.

[11]  H. Weiner,et al.  Activation of CD25+CD4+ Regulatory T Cells by Oral Antigen Administration1 , 2001, The Journal of Immunology.

[12]  W. Strober,et al.  Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β , 2001, The Journal of experimental medicine.

[13]  D. Umetsu,et al.  Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen , 2001, Nature Immunology.

[14]  E. Shevach,et al.  Cutting Edge: Control of CD8+ T Cell Activation by CD4+CD25+ Immunoregulatory Cells , 2001, The Journal of Immunology.

[15]  A. Khoruts,et al.  Generation of Anergic and Potentially Immunoregulatory CD25+CD4 T Cells In Vivo After Induction of Peripheral Tolerance with Intravenous or Oral Antigen1 , 2001, The Journal of Immunology.

[16]  M. Roncarolo,et al.  Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function , 2001, The Journal of experimental medicine.

[17]  H. Cantor,et al.  Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. , 2001, Journal of autoimmunity.

[18]  D. Mason,et al.  CD25 Is a Marker for CD4+ Thymocytes That Prevent Autoimmune Diabetes in Rats, But Peripheral T Cells with This Function Are Found in Both CD25+ and CD25− Subpopulations1 , 2000, The Journal of Immunology.

[19]  T. Mak,et al.  Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4 , 2000, The Journal of experimental medicine.

[20]  Fiona Powrie,et al.  Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation , 2000, The Journal of experimental medicine.

[21]  A. Cumano,et al.  Regulatory CD4 T Cells Control the Size of the Peripheral Activated/Memory CD4 T Cell Compartment1 , 2000, The Journal of Immunology.

[22]  W. Heath,et al.  A Bone Marrow-Derived APC in the Gut-Associated Lymphoid Tissue Captures Oral Antigens and Presents Them to Both CD4+ and CD8+ T Cells1 , 2000, The Journal of Immunology.

[23]  J. Kehren,et al.  Oral Administration of Hapten Inhibits In Vivo Induction of Specific Cytotoxic CD8+ T Cells Mediating Tissue Inflammation: A Role for Regulatory CD4+ T Cells1 , 2000, The Journal of Immunology.

[24]  Fiona Powrie,et al.  An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation , 1999, The Journal of experimental medicine.

[25]  A. Iwasaki,et al.  Freshly Isolated Peyer's Patch, but Not Spleen, Dendritic Cells Produce Interleukin 10 and Induce the Differentiation of T Helper Type 2 Cells , 1999, The Journal of experimental medicine.

[26]  J. Sun,et al.  Antigen-specific T cell activation and proliferation during oral tolerance induction. , 1999, Journal of Immunology.

[27]  M. Hahne,et al.  Cytotoxicity Is Mandatory for CD8+ T Cell–mediated Contact Hypersensitivity , 1999, The Journal of experimental medicine.

[28]  Y. Chien,et al.  Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen. , 1998, Immunity.

[29]  Hervé Groux,et al.  A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis , 1997, Nature.

[30]  R. Fairchild,et al.  Development of effector CD8+ T cells in contact hypersensitivity occurs independently of CD4+ T cells. , 1997, Journal of immunology.

[31]  J. Nicolas,et al.  Lack of oral tolerance but oral priming for contact sensitivity to dinitrofluorobenzene in major histocompatibility complex class II‐deficient mice and in CD4+ T cell‐depleted mice , 1996, European journal of immunology.

[32]  S. Sakaguchi,et al.  Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation , 1996, The Journal of experimental medicine.

[33]  R. Fairchild,et al.  T cell populations primed by hapten sensitization in contact sensitivity are distinguished by polarized patterns of cytokine production: interferon gamma-producing (Tc1) effector CD8+ T cells and interleukin (Il) 4/Il-10-producing (Th2) negative regulatory CD4+ T cells , 1996, The Journal of experimental medicine.

[34]  C. Janeway,et al.  Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[35]  J. Revillard,et al.  Major histocompatibility complex class I‐restricted CD8+ T cells and class II‐restricted CD4+ T cells, respectively, mediate and regulate contact sensitivity to dinitrofluorobenzene , 1995, European journal of immunology.

[36]  F. Alt,et al.  Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment. , 1995, Immunity.

[37]  H. Weiner,et al.  Peripheral deletion of antigen-reactive T cells in oral tolerance , 1995, Nature.

[38]  D. Kaiserlian,et al.  Oral tolerance to haptens: intestinal epithelial cells from 2,4‐dinitrochlorobenzene‐fed mice inhibit hapten‐specific T cell activation in vitro , 1995, European journal of immunology.

[39]  H. Weiner,et al.  Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. , 1994, Science.

[40]  C. Benezra,et al.  Optimization of the mouse ear swelling test for in vivo and in vitro studies of weak contact sensitizers * , 1994, Contact dermatitis.

[41]  A. Feller,et al.  Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene , 1993, Cell.

[42]  S. Tonegawa,et al.  Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice , 1993, Cell.

[43]  K. Rajewsky,et al.  Interleukin-10-deficient mice develop chronic enterocolitis , 1993, Cell.

[44]  D. Melamed,et al.  Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin , 1993, European journal of immunology.

[45]  C. Benoist,et al.  Mice lacking the MHC class II-associated invariant chain , 1993, Cell.

[46]  R. Steinman,et al.  Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor , 1992, The Journal of experimental medicine.

[47]  G. Proetzel,et al.  Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease , 1992, Nature.

[48]  C. Orosz,et al.  Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy. , 1991, Journal of immunology.

[49]  D. Gray,et al.  Mice lacking MHC class II molecules , 1991, Cell.