Omics Approaches to Identify Potential Biomarkers of Inflammatory Diseases in the Focal Adhesion Complex
暂无分享,去创建一个
[1] P. Nighot,et al. Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88 , 2015, The Journal of Immunology.
[2] N. Suttorp,et al. Rac1 Regulates the NLRP3 Inflammasome Which Mediates IL-1beta Production in Chlamydophila pneumoniae Infected Human Mononuclear Cells , 2012, PloS one.
[3] Edwin Wang,et al. Cancer systems biology in the genome sequencing era: part 1, dissecting and modeling of tumor clones and their networks. , 2013, Seminars in cancer biology.
[4] J. Beaulieu,et al. Integrin/Fak/Src-mediated regulation of cell survival and anoikis in human intestinal epithelial crypt cells: selective engagement and roles of PI3-K isoform complexes , 2012, Apoptosis.
[5] Yongshuai Jiang,et al. Integrative analysis of genome-wide association studies and gene expression analysis identifies pathways associated with rheumatoid arthritis , 2016, Oncotarget.
[6] Brad T. Sherman,et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery , 2003, Genome Biology.
[7] R. Jamal,et al. Integrated microRNA, gene expression and transcription factors signature in papillary thyroid cancer with lymph node metastasis , 2016, PeerJ.
[8] S. Nakashima. Protein kinase C alpha (PKC alpha): regulation and biological function. , 2002, Journal of biochemistry.
[9] W. H. Goldmann,et al. Mechanosensation: a basic cellular process. , 2014, Progress in molecular biology and translational science.
[10] Clare M. Waterman,et al. Integration of actin dynamics and cell adhesion by a three-dimensional, mechanosensitive molecular clutch , 2015, Nature Cell Biology.
[11] Zhiwei Cao,et al. Largescale Transcriptomics Analysis Suggests Over-Expression of BGH3, MMP9 and PDIA3 in Oral Squamous Cell Carcinoma , 2016, PloS one.
[12] N. Zeleznik-Le,et al. FAK mediates a compensatory survival signal parallel to PI3K-AKT in PTEN-null T-ALL cells. , 2015, Cell reports.
[13] I. Chung,et al. Rheumatoid Arthritis: The Stride from Research to Clinical Practice , 2016, International journal of molecular sciences.
[14] J. Söderholm,et al. Importance of disrupted intestinal barrier in inflammatory bowel diseases , 2011, Inflammatory bowel diseases.
[15] Qing-quan Li,et al. Involvement of EGFR in the promotion of malignant properties in multidrug resistant breast cancer cells. , 2011, International journal of oncology.
[16] Matthew E. Ritchie,et al. limma powers differential expression analyses for RNA-sequencing and microarray studies , 2015, Nucleic acids research.
[17] Mechanoaccumulative Elements of the Mammalian Actin Cytoskeleton , 2016, Current Biology.
[18] R. Perlis,et al. Translating biomarkers to clinical practice , 2011, Molecular Psychiatry.
[19] M. Matsuda,et al. Ankyrin repeat domain 28 (ANKRD28), a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation. , 2009, Experimental cell research.
[20] K. Aldape,et al. FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST. , 2009, Molecular cell.
[21] B. Becher,et al. NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22. , 2016, The Journal of clinical investigation.
[22] Thomas Mikeska,et al. DNA Methylation Biomarkers: Cancer and Beyond , 2014, Genes.
[23] Mehrdad Mehrbod,et al. Mechanotransduction pathways linking the extracellular matrix to the nucleus. , 2014, International review of cell and molecular biology.
[24] P. Dube,et al. Integrin-Mediated First Signal for Inflammasome Activation in Intestinal Epithelial Cells , 2014, The Journal of Immunology.
[25] M. Longaker,et al. Scarless wound healing: finding the right cells and signals , 2016, Cell and Tissue Research.
[26] Xin Yu,et al. Regulation of β-catenin transcription activity by leupaxin in hepatocellular carcinoma , 2016, Tumor Biology.
[27] J. Pekow,et al. The emerging role of miRNAs in inflammatory bowel disease: a review , 2015, Therapeutic advances in gastroenterology.
[28] Wei-Guo Zhu,et al. Kindlin 2 forms a transcriptional complex with β‐catenin and TCF4 to enhance Wnt signalling , 2012, EMBO reports.
[29] Marina Vannucci,et al. A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells , 2016, PLoS Comput. Biol..
[30] E. Elinav,et al. Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis , 2015, Cell.
[31] B. Goud,et al. Integrin endosomal signalling suppresses anoikis , 2015, Nature Cell Biology.
[32] G. D'Haens,et al. Performance of Common Disease Activity Markers as a Reflection of Inflammatory Burden in Ulcerative Colitis , 2016, Inflammatory bowel diseases.
[33] A. Bouton,et al. Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events , 2011, Journal of leukocyte biology.
[34] W. Sandborn,et al. Predicting relapse in patients with inflammatory bowel disease: what is the role of biomarkers? , 2005, Gut.
[35] Gary D. Bader,et al. An automated method for finding molecular complexes in large protein interaction networks , 2003, BMC Bioinformatics.
[36] J. Haugh,et al. JCB_201406102 1..13 , 2015 .
[37] Weiwei Yang,et al. Ras-Induced and Extracellular Signal-Regulated Kinase 1 and 2 Phosphorylation-Dependent Isomerization of Protein Tyrosine Phosphatase (PTP)-PEST by PIN1 Promotes FAK Dephosphorylation by PTP-PEST , 2011, Molecular and Cellular Biology.
[38] Jane Worthington,et al. A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus , 2016, Annals of the rheumatic diseases.
[39] C. McCulloch,et al. The Recruitment of the Interleukin-1 (IL-1) Receptor-associated Kinase (IRAK) into Focal Adhesion Complexes Is Required for IL-1β-induced ERK Activation* , 2000, The Journal of Biological Chemistry.
[40] G. Downey,et al. A ternary complex comprising FAK, PTPα and IP3 receptor 1 functionally engages focal adhesions and the endoplasmic reticulum to mediate IL-1-induced Ca2+ signalling in fibroblasts. , 2016, The Biochemical journal.
[41] T. Natsume,et al. Wnt signalling regulates paxillin ubiquitination essential for mesodermal cell motility , 2007, Nature Cell Biology.
[42] L. Lim,et al. PAK Is Regulated by PI3K, PIX, CDC42, and PP2Cα and Mediates Focal Adhesion Turnover in the Hyperosmotic Stress-induced p38 Pathway* , 2008, Journal of Biological Chemistry.
[43] Wei Wang,et al. DNA methylome signature in rheumatoid arthritis , 2012, Annals of the rheumatic diseases.
[44] Christian von Mering,et al. STRING: known and predicted protein–protein associations, integrated and transferred across organisms , 2004, Nucleic Acids Res..
[45] K. Armstrong,et al. Investigating micronutrients and epigenetic mechanisms in relation to inflammatory bowel disease. , 2010, Mutation research.
[46] Liye Ma,et al. Integrated miRNA–risk gene–pathway pair network analysis provides prognostic biomarkers for gastric cancer , 2016, OncoTargets and therapy.
[47] E. Garí,et al. Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin , 2016, Nature Communications.
[48] Xing Chen,et al. HGIMDA: Heterogeneous graph inference for miRNA-disease association prediction , 2016, Oncotarget.
[49] R. García-Mata,et al. I’m coming to GEF you: Regulation of RhoGEFs during cell migration , 2014, Cell adhesion & migration.
[50] P. Das,et al. Proteome analysis of the macroscopically affected colonic mucosa of Crohn’s disease and intestinal tuberculosis , 2016, Scientific Reports.
[51] T. Tsuruo,et al. β1 integrin/Fak/Src signaling in intestinal epithelial crypt cell survival: integration of complex regulatory mechanisms , 2008, Apoptosis.
[52] Mona Singh,et al. Computational solutions for omics data , 2013, Nature Reviews Genetics.
[53] Alex Boussioutas,et al. Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients , 2016, Oncotarget.
[54] R. Plenge,et al. Genetic variants that predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis: current challenges and future directions , 2008, Current opinion in rheumatology.
[55] Hiroyuki Ogata,et al. KEGG: Kyoto Encyclopedia of Genes and Genomes , 1999, Nucleic Acids Res..
[56] M. Fu,et al. Screening of gene signatures for rheumatoid arthritis and osteoarthritis based on bioinformatics analysis , 2016, Molecular medicine reports.
[57] K. Nose,et al. Involvement of FAK and PTP-PEST in the regulation of redox-sensitive nuclear-cytoplasmic shuttling of a LIM protein, Hic-5. , 2005, Antioxidants & redox signaling.
[58] J-K Wang,et al. The functional analysis of MicroRNAs involved in NF-κB signaling. , 2016, European review for medical and pharmacological sciences.
[59] T. Vomastek,et al. Symmetry breaking in spreading RAT2 fibroblasts requires the MAPK/ERK pathway scaffold RACK1 that integrates FAK, p190A-RhoGAP and ERK2 signaling. , 2016, Biochimica et biophysica acta.
[60] G. Stouffer,et al. beta(3)-Integrin cytoplasmic binding proteins. , 2004, Archivum immunologiae et therapiae experimentalis.
[61] B. Geiger,et al. Environmental sensing through focal adhesions , 2009, Nature Reviews Molecular Cell Biology.
[62] M. Mann,et al. Decoding signalling networks by mass spectrometry-based proteomics , 2010, Nature Reviews Molecular Cell Biology.
[63] H. Ikeuchi,et al. Activation of focal adhesion kinase via M1 muscarinic acetylcholine receptor is required in restitution of intestinal barrier function after epithelial injury. , 2014, Biochimica et biophysica acta.
[64] Xing Chen,et al. IRWRLDA: improved random walk with restart for lncRNA-disease association prediction , 2016, Oncotarget.
[65] S. Honda,et al. SHPS‐1 negatively regulates integrin αIIbβ3 function through CD47 without disturbing FAK phosphorylation , 2005 .
[66] V. Ambros,et al. Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning. , 2004, Methods in molecular biology.
[67] Suxia Han,et al. fied, along with their associated protein‐protein interaction networks and Kyoto Encyclopedia of Genes and Genomes , 2019 .
[68] S. Itzkovitz,et al. Functional atlas of the integrin adhesome , 2007, Nature Cell Biology.
[69] M. Suico,et al. Promoter hypomethylation of Toll‐like receptor‐2 gene is associated with increased proinflammatory response towardbacterial peptidoglycan in cystic fibrosis bronchial epithelial cells , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[70] Andrew W. Holle,et al. High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation. , 2016, Integrative biology : quantitative biosciences from nano to macro.
[71] L. Croner,et al. Combined Serological, Genetic, and Inflammatory Markers Differentiate Non-IBD, Crohn's Disease, and Ulcerative Colitis Patients , 2013, Inflammatory bowel diseases.
[72] G. Giamas,et al. Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer , 2014, Expert review of proteomics.
[73] R. Hällgren,et al. Evaluation of biomarkers for ulcerative colitis comparing two sampling methods: fecal markers reflect colorectal inflammation both macroscopically and on a cellular level , 2016, Scandinavian journal of clinical and laboratory investigation.
[74] Jingxue Xin,et al. Identifying network biomarkers based on protein-protein interactions and expression data , 2015, BMC Medical Genomics.
[75] D. Weaver. A1-adenosine receptor gene expression in fetal rat brain. , 1996, Brain research. Developmental brain research.
[76] Mathieu Lemire,et al. Common variants in the NLRP3 region contribute to Crohn's disease susceptibility , 2009, Nature Genetics.
[77] O. Omran,et al. Cytoskeletal Focal Adhesion Proteins Fascin-1 and Paxillin Are Predictors of Malignant Progression and Poor Prognosis in Human Breast Cancer. , 2015, Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
[78] H. Genth,et al. Difference in F-Actin Depolymerization Induced by Toxin B from the Clostridium difficile Strain VPI 10463 and Toxin B from the Variant Clostridium difficile Serotype F Strain 1470 , 2013, Toxins.
[79] S. Simon,et al. Leukocyte Function Antigen-1, Kindlin-3, and Calcium Flux Orchestrate Neutrophil Recruitment during Inflammation , 2012, The Journal of Immunology.
[80] M. Ichiba,et al. Abl-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion. , 2012, The Biochemical journal.
[81] S. Nakashima. Protein kinase Cα (PKCα): Regulation and biological function , 2002 .