Validity and Applicability of the Global Leadership Initiative on Malnutrition (GLIM) Criteria in Patients Hospitalized for Acute Medical Conditions

(1) Background: The objectives of this study were to evaluate the concurrent and predictive validity and the applicability of the global leadership initiative on malnutrition (GLIM) criteria in patients hospitalized for acute medical conditions. (2) Methods: prospective cohort study with patients hospitalized for acute medical conditions. For validation, the methodology proposed by the GLIM group of experts was used. Sensitivity and specificity values greater than 80% with respect to those for the subjective global assessment (SGA) were necessary for concurrent validation. The time necessary to complete each nutritional assessment test was determined. (3) Results: A total of 119 patients were evaluated. The SGA was applied to the entire cohort, but the GLIM criteria could not be applied to 3.4% of the patients. The sensitivity and specificity of the GLIM criteria with respect to those for the SGA to detect malnutrition were 78.0 and 86.2%, respectively. The GLIM predictive validity criterion was fulfilled because patients with malnutrition more frequently had a hospital stay >10 days (odds ratio of 2.98 (1.21–7.60)). The GLIM criteria required significantly more time for completion than did the SGA (p = 0.006). (4) Conclusion: The results of this study do not support the use of the GLIM criteria over the SGA for the diagnosis of malnutrition in patients hospitalized for acute medical conditions.

[1]  Yaxin Zhang,et al.  Validation of GLIM criteria on malnutrition in older Chinese inpatients , 2022, Frontiers in Nutrition.

[2]  M. Miller,et al.  The ability of the Global Leadership Initiative on Malnutrition (GLIM) to diagnose protein–energy malnutrition in patients requiring vascular surgery: a validation study , 2022, British Journal of Nutrition.

[3]  Guohao Wu,et al.  Validation of GLIM malnutrition criteria in cancer patients undergoing major abdominal surgery: A large-scale prospective study. , 2022, Clinical nutrition.

[4]  G. Wanten,et al.  Evaluation of the Validity and Feasibility of the GLIM Criteria Compared with PG-SGA to Diagnose Malnutrition in Relation to One-Year Mortality in Hospitalized Patients. , 2021, Journal of the Academy of Nutrition and Dietetics.

[5]  N. Kiss,et al.  Comparison of the GLIM, ESPEN and ICD-10 Criteria to Diagnose Malnutrition and Predict 30-Day Outcomes: An Observational Study in an Oncology Population , 2021, Nutrients.

[6]  Yin Li,et al.  Good performance of the Global Leadership Initiative on Malnutrition criteria for diagnosing and classifying malnutrition in people with esophageal cancer undergoing esophagectomy. , 2021, Nutrition.

[7]  J. J. de la Cruz,et al.  SeDREno study - prevalence of hospital malnutrition according to GLIM criteria, ten years after the PREDyCES study. , 2021, Nutricion hospitalaria.

[8]  S. Heymsfield,et al.  Calf circumference: cutoff values from the NHANES 1999-2006. , 2021, The American journal of clinical nutrition.

[9]  Victória Silva Chites,et al.  GLIM criteria for malnutrition diagnosis of hospitalized patients presents satisfactory criterion validity: A prospective cohort study. , 2021, Clinical nutrition.

[10]  Yu Zhu,et al.  Prevalence of malnutrition comparing NRS2002, MUST, and PG-SGA with the GLIM criteria in adults with cancer: A multi-center study. , 2020, Nutrition.

[11]  M. Cankurtaran,et al.  Comparison of the Efficacy of GLIM Criteria, SGA and NRS-2002 in Diagnosing Malnutrition and Predicting 5-Year Mortality in Patients Hospitalized for Acute Illnesses. , 2020, JPEN. Journal of parenteral and enteral nutrition.

[12]  J. Reginster,et al.  Mortality in malnourished older adults diagnosed by ESPEN and GLIM criteria in the SarcoPhAge study , 2020, Journal of cachexia, sarcopenia and muscle.

[13]  Matthias Pirlich,et al.  Global Leadership Initiative on Malnutrition (GLIM): Guidance on Validation of the Operational Criteria for the Diagnosis of Protein-Energy Malnutrition in Adults. , 2020, JPEN. Journal of parenteral and enteral nutrition.

[14]  C. Compher,et al.  Global Leadership Initiative on Malnutrition (GLIM): Guidance on validation of the operational criteria for the diagnosis of protein-energy malnutrition in adults. , 2020, Clinical nutrition.

[15]  F. Bellanti,et al.  Comparison of Three Nutritional Screening Tools with the New Glim Criteria for Malnutrition and Association with Sarcopenia in Hospitalized Older Patients , 2020, Journal of clinical medicine.

[16]  H. Keller,et al.  GLIM criteria has fair sensitivity and specificity for diagnosing malnutrition when using SGA as comparator. , 2019, Clinical nutrition.

[17]  Maurizio Marra,et al.  Assessment of Body Composition in Health and Disease Using Bioelectrical Impedance Analysis (BIA) and Dual Energy X-Ray Absorptiometry (DXA): A Critical Overview , 2019, Contrast media & molecular imaging.

[18]  A. Gossum,et al.  GLIM criteria for the diagnosis of malnutrition - A consensus report from the global clinical nutrition community. , 2019, Clinical nutrition.

[19]  A. Gossum,et al.  GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community , 2019, Journal of cachexia, sarcopenia and muscle.

[20]  A. Gossum,et al.  GLIM Criteria for the Diagnosis of Malnutrition: A Consensus Report From the Global Clinical Nutrition Community. , 2018, JPEN. Journal of parenteral and enteral nutrition.

[21]  J. da Silva Fink,et al.  Subjective global assessment of nutritional status – A systematic review of the literature. , 2015, Clinical nutrition.

[22]  P. Garcia-Lorda,et al.  Prevalence and costs of malnutrition in hospitalized patients; the PREDyCES Study. , 2012, Nutricion hospitalaria.

[23]  Maria Manera,et al.  Incorporación del dietista-nutricionista en el Sistema Nacional de Salud (SNS): Declaración de Postura de la Asociación Española de Dietistas-Nutricionistas (AEDN) , 2009 .

[24]  Claude Pichard,et al.  Prognostic impact of disease-related malnutrition. , 2008, Clinical nutrition.

[25]  C. Corish,et al.  Protein-energy undernutrition in hospital in-patients. , 2000, The British journal of nutrition.

[26]  S. Kamath,et al.  Hospital malnutrition: a 33-hospital screening study. , 1986, Journal of the American Dietetic Association.

[27]  G. Blackburn,et al.  Prevalence of malnutrition in general medical patients. , 1976, JAMA.

[28]  R. Joynt.  Department , 1960, Neurology.

[29]  C. Mackenzie,et al.  A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. , 1987, Journal of chronic diseases.