Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction

[1]  Mark S. Schmidt,et al.  Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures , 2019, Cell reports.

[2]  S. Bruzzone,et al.  Slc12a8 is a nicotinamide mononucleotide transporter , 2018, Nature Metabolism.

[3]  A. Ferry,et al.  Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training , 2018, Front. Physiol..

[4]  Tianyuan Wang,et al.  Mitochondrial acetyl-CoA reversibly regulates locus-specific histone acetylation and gene expression , 2018, Life Science Alliance.

[5]  J. Rabinowitz,et al.  Nicotinamide adenine dinucleotide is transported into mammalian mitochondria , 2018, eLife.

[6]  E. White,et al.  Quantitative Analysis of NAD Synthesis-Breakdown Fluxes. , 2018, Cell metabolism.

[7]  B. Jensen,et al.  Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle. , 2018, American journal of physiology. Endocrinology and metabolism.

[8]  M. McQueen,et al.  Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults , 2018, Nature Communications.

[9]  C. Brenner,et al.  Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy , 2017, Circulation.

[10]  G. Lavery,et al.  Cellular and genetic models of H6PDH and 11β‐HSD1 function in skeletal muscle , 2017, Cell biochemistry and function.

[11]  C. Brenner,et al.  Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells , 2017, Molecular metabolism.

[12]  T. Abel,et al.  ACETYL-COA SYNTHETASE REGULATES HISTONE ACETYLATION AND HIPPOCAMPAL MEMORY , 2017, Nature..

[13]  J. Auwerx,et al.  NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells , 2016, Nature Communications.

[14]  Mark S. Schmidt,et al.  Nicotinamide riboside is uniquely and orally bioavailable in mice and humans , 2016, Nature Communications.

[15]  D. Sinclair,et al.  Head to Head Comparison of Short-Term Treatment with the NAD+ Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice , 2016, Front. Pharmacol..

[16]  B. Gregory,et al.  Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. , 2016, Cell metabolism.

[17]  R. Aebersold,et al.  NAD+ repletion improves mitochondrial and stem cell function and enhances life span in mice , 2016, Science.

[18]  D. Ricke,et al.  In vivo Monitoring of Transcriptional Dynamics After Lower-Limb Muscle Injury Enables Quantitative Classification of Healing , 2015, Scientific Reports.

[19]  W. Kiess,et al.  Physiological and pathophysiological roles of NAMPT and NAD metabolism , 2015, Nature Reviews Endocrinology.

[20]  Christian Appenzeller‐Herzog,et al.  The antioxidant machinery of the endoplasmic reticulum: Protection and signaling. , 2015, Free radical biology & medicine.

[21]  David S. Wishart,et al.  MetaboAnalyst 3.0—making metabolomics more meaningful , 2015, Nucleic Acids Res..

[22]  B. Tu,et al.  Acetyl-CoA and the Regulation of Metabolism: Mechanisms and Consequences , 2015, Current opinion in cell biology.

[23]  P. Oliveri,et al.  NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms , 2015, Proceedings of the National Academy of Sciences.

[24]  J. Auwerx,et al.  Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3 , 2014, EMBO molecular medicine.

[25]  Sander M Houten,et al.  Mitochondrial protein acetylation is driven by acetyl-CoA from fatty acid oxidation. , 2014, Human molecular genetics.

[26]  C. Cantó,et al.  Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes. , 2013, Molecular aspects of medicine.

[27]  K. McCormick,et al.  Evidence that adrenal hexose-6-phosphate dehydrogenase can effect microsomal P450 cytochrome steroidogenic enzymes. , 2013, Biochimica et biophysica acta.

[28]  Sean D. Mooney,et al.  Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways , 2013, Proceedings of the National Academy of Sciences.

[29]  G. Lavery,et al.  Novel H6PDH mutations in two girls with premature adrenarche: ‘apparent’ and ‘true’ CRD can be differentiated by urinary steroid profiling , 2012, European journal of endocrinology.

[30]  S. Schenk,et al.  NAD(+)/NADH and skeletal muscle mitochondrial adaptations to exercise. , 2012, American journal of physiology. Endocrinology and metabolism.

[31]  G. Reynolds,et al.  Lack of Significant Metabolic Abnormalities in Mice with Liver-Specific Disruption of 11β-Hydroxysteroid Dehydrogenase Type 1 , 2012, Endocrinology.

[32]  David S. Wishart,et al.  MetaboAnalyst 2.0—a comprehensive server for metabolomic data analysis , 2012, Nucleic Acids Res..

[33]  P. Neufer,et al.  Lipid-induced mitochondrial stress and insulin action in muscle. , 2012, Cell metabolism.

[34]  K. Suhre,et al.  Procedure for tissue sample preparation and metabolite extraction for high-throughput targeted metabolomics , 2012, Metabolomics.

[35]  Enxuan Jing,et al.  Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production , 2011, Proceedings of the National Academy of Sciences.

[36]  Jianguo Xia,et al.  Web-based inference of biological patterns, functions and pathways from metabolomic data using MetaboAnalyst , 2011, Nature Protocols.

[37]  G. Lavery,et al.  Biochemistry and physiology of hexose-6-phosphate knockout mice , 2011, Molecular and Cellular Endocrinology.

[38]  D. McMillan,et al.  Contribution of hexose-6-phosphate dehydrogenase to NADPH content and redox environment in the endoplasmic reticulum , 2010, Redox report : communications in free radical research.

[39]  João Wosniak,et al.  Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase. , 2009, Antioxidants & redox signaling.

[40]  D. McMillan,et al.  Physiological roles of 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase , 2008, Current opinion in pediatrics.

[41]  G. Lavery,et al.  Lack of hexose-6-phosphate dehydrogenase impairs lipid mobilization from mouse adipose tissue. , 2008, Endocrinology.

[42]  Francesco Falciani,et al.  Deletion of Hexose-6-phosphate Dehydrogenase Activates the Unfolded Protein Response Pathway and Induces Skeletal Myopathy* , 2008, Journal of Biological Chemistry.

[43]  C. Brenner,et al.  Saccharomyces cerevisiae YOR071C Encodes the High Affinity Nicotinamide Riboside Transporter Nrt1* , 2008, Journal of Biological Chemistry.

[44]  D. McMillan,et al.  Abnormalities of glucose homeostasis and the hypothalamic-pituitary-adrenal axis in mice lacking hexose-6-phosphate dehydrogenase. , 2007, Endocrinology.

[45]  D. McMillan,et al.  Hexose 6-phosphate dehydrogenase (H6PD) and corticosteroid metabolism , 2007, Molecular and Cellular Endocrinology.

[46]  J. Milbrandt,et al.  Stimulation of Nicotinamide Adenine Dinucleotide Biosynthetic Pathways Delays Axonal Degeneration after Axotomy , 2006, The Journal of Neuroscience.

[47]  Eric Verdin,et al.  Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2 , 2006, Proceedings of the National Academy of Sciences.

[48]  W. C. Hallows,et al.  Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases , 2006, Proceedings of the National Academy of Sciences.

[49]  P. White,et al.  Hexose-6-phosphate Dehydrogenase Knock-out Mice Lack 11β-Hydroxysteroid Dehydrogenase Type 1-mediated Glucocorticoid Generation* , 2006, Journal of Biological Chemistry.

[50]  Lyubomir G. Nashev,et al.  Hexose‐6‐phosphate dehydrogenase determines the reaction direction of 11β‐hydroxysteroid dehydrogenase type 1 as an oxoreductase , 2004, FEBS letters.

[51]  D. Ray,et al.  Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency , 2003, Nature Genetics.

[52]  D. Hale,et al.  Molecular basis of human mitochondrial very-long-chain acyl-CoA dehydrogenase deficiency causing cardiomyopathy and sudden death in childhood. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[53]  P. Kaplan,et al.  Marked elevation of urinary 3-hydroxydecanedioic acid in a malnourished infant with glycogen storage disease, mimicking long-chainl-3-hydroxyacyl-CoA dehydrogenase deficiency , 1993, Journal of Inherited Metabolic Disease.

[54]  D. Kerr,et al.  Urinary 3-hydroxydicarboxylic acids in pathophysiology of metabolic disorders with dicarboxylic aciduria. , 1991, Metabolism: clinical and experimental.

[55]  K. Parker,et al.  Hexose-6-phosphate dehydrogenase contributes to skeletal muscle homeostasis independent of 11β-hydroxysteroid dehydrogenase type 1. , 2011, Endocrinology.

[56]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..