Further advances in the chemistry of mannich bases

[1]  H. Chao.  The Reduction of Mannich Bases and Their Derivatives by Tri-N-Butyltin Hydride , 1988 .

[2]  L. Angiolini,et al.  Mannich bases in polymer chemistry , 1988 .

[3]  J. M. Roper,et al.  Direct synthesis of spiro[5.5]undeca-1,4,7-trienones from phenols via a quinone methide intermediate , 1988 .

[4]  L. Overman,et al.  Synthesis applications of cationic aza-Cope rearrangements. Part 17. Transition-state geometry of [3,3]-sigmatropic rearrangements of iminium ions , 1988 .

[5]  S. A. Patil,et al.  Evaluation of acrylophenones and related bis-Mannich bases against murine P388 leukemia , 1987 .

[6]  A. J. Marisca,et al.  Methanesulfonanilides and the Mannich reaction , 1987 .

[7]  G. Butler,et al.  Preparation of Water-Soluble Polymers via the Mannich Reaction , 1987 .

[8]  P. Grieco,et al.  Reactions of allylstannanes with in situ generated immonium salts in protic solvent: a facile aminomethano destannylation process , 1987 .

[9]  D. Russowsky,et al.  Secondary Mannich bases via trimethylsilyl trifluoromethanesulphonate promoted addition of silyl enol ethers to Schiff bases , 1987 .

[10]  M. Fedtke.  Acceleration mechanisms in curing reactions involving model systems , 1987 .

[11]  O. Babot,et al.  A convenient regioselective synthesis of Mannich bases , 1986 .

[12]  J. Hodgkin.  Linear aminophenol polymers using the mannich reaction , 1986 .

[13]  E. Llama,et al.  Synthesis and structural study of new derivatives of 6,8-diaryl-3-thia-7-azabicyclo[3.3.1]nonane systems , 1986 .

[14]  K. Berlin,et al.  Synthesis of 3-selena-7-azabicyclo[3.3.1]nonanes and certain derivatives , 1986 .

[15]  H. Rapoport,et al.  Synthesis of optically pure .DELTA.4-tetrahydroquinolinic acids and hexahydroindolo[2,3-a]quinolizines from L-aspartic acid. Racemization on the route to vindoline , 1986 .

[16]  O. Babot,et al.  A new convenient synthesis of dialkyl(methylene)ammonium chloride , 1986 .

[17]  H. Kinoshita,et al.  A NEW AND EFFECTIVE AMINOMETHYLATION BY THE USE OF N-(p-TOLUENESULFONYLMETHYL)-p-TOLUENESULFONAMIDE AS AN EQUIVALENT OF METHANIMINE. A CONVENIENT PREPARATION OF PYRROLE COMPOUNDS , 1986 .

[18]  K. Ikeda,et al.  Trifluoromethanesulfonic Acid-Promoted Reaction of Hexahydro-1, 3, 5-triazines.Introduction of a Secondary Aminomethyl Grouping into Carboxylates at the α-Position through Ketene Silyl Acetals , 1986 .

[19]  H. Möhrle,et al.  Reaktionsverhalten von En‐Derivaten monosubstituierter Hydrazine unter Mannich‐Bedingungen , 1986 .

[20]  H. Möhrle,et al.  Reaktion von 5,5‐Dimethyl‐3‐trimethylhydrazino‐2‐cyclohexen‐1‐on mit Methyleniminiumsalzen , 1986 .

[21]  M. S. Cooper,et al.  Mannich reactions of aryl-trialkylstannanes using preformed dialkyl-methyleneiminium salts , 1986 .

[22]  K. Shishido,et al.  An efficient and highly regioselective intramolecular Mannich-type reaction: A construction of the AEF ring system of aconitine-type diterpene alkaloids , 1986 .

[23]  A. Curulli,et al.  Electrophilic heteroaromatic substitutions. 8. Studies on the mechanism of the .alpha.-side-chain aminomethylation and hydrogen/deuterium isotope exchange reactions of .alpha.-methylpyrroles , 1985 .

[24]  W. Hamama,et al.  Pictet-Spengler reactions of Tryptamine and tryptophan with cycloalkanones and ketonicMannich bases , 1985 .

[25]  C. H. Kim,et al.  Synthesis of 6-phenyl-3-azabicyclo[4.2.1]nonane , 1985 .

[26]  P. Yates,et al.  The Mannich reaction. 1-Alkyl-3,3-diphenyl-4-piperidinones, 1,6'-dialkyl-3',4',5',6',7',8'-hexahydro-5,5,8',8'-tetraphenylspiro[piperidine-3,2'-[2H]pyrano[3,2-c]pyridin]-4-ones and their derivatives , 1985 .

[27]  H. Möhrle,et al.  Aminomethylierung von 1,3-Diketonen , 1985 .

[28]  H. Möhrle,et al.  Die tatsächliche Struktur der scheinbar vom 1-(8-Hydroxychinol-5-yl)-3-phenylpropan-1,3-dion abgeleiteten Wirkstoffe , 1985 .

[29]  R. Troschütz,et al.  Heterocyclen via Mannichbasen, 8. Mitt. 7,8‐Dihydro‐1,6‐naphthyridin‐5(6H)‐one , 1985 .

[30]  P. Bravo,et al.  Alkylation of 4-Hydroxycoumarins by Ketone Mannich Bases. Synthesis of 4-Hydroxy-2-oxo-3-(3-oxoalkyl)-2H-1-benzopyrans , 1985 .

[31]  R. Haller,et al.  Konformere 3‐Oxa‐7‐azabicyclo[3.3.1]nonanone und ihre Reduktionsprodukte , 1985 .

[32]  H. Möhrle,et al.  Konkurrierende Reaktion der Phenol- und 1,3-dicarbonyl-Funktion unter Mannichbedingungen , 1985 .

[33]  H. Bundgaard.  Formation of prodrugs of amines, amides, ureides, and imides. , 1985, Methods in enzymology.

[34]  H. W. Reinhardt,et al.  Aminomethylierung vinyloger Cyanamide. , 1984 .

[35]  D. Seebach,et al.  Diastereoselektive synthese neuartiger Mannich-Basen mittels titanderivaten, vorläufige mitteilung†‡ , 1984 .

[36]  B. Rigo,et al.  Etude dans la série des pyrrolidinones: Réaction de mannich du glutamate de diéthyle , 1984 .

[37]  J. Petersen,et al.  Synthesis of (.+-.)-.omega.-aza[x.y.1]bicycloalkanes by an intramolecular Mannich reaction , 1984 .

[38]  M. Abou-Elzahab,et al.  A study on the doubleMannich reaction with 1,3-diphenylacetone , 1984 .

[39]  Kiyoshi Matsumoto,,et al.  Mannich Reaction Under High Pressee. Dimethylaminomethylation of Ketones with bis(Diyethylamino)methane under Mild Conditions , 1984 .

[40]  M. Metwally,et al.  Synthesis of 2,5-bis(piperidinomethyl)piperidine and 1,5-bis(aminomethyl)-3-azabicyclo[3.2.1]octanones , 1984 .

[41]  G. Brochu,et al.  Electrochemical oxidation of 4-substituted N,N-dimethylaniline in the presence of silyl enol ether. Effect of the substituent on the formation of Mannich bases. II , 1984 .

[42]  H. W. Reinhardt,et al.  β‐Aminoenone als Komponenten in der Mannich‐Reaktion , 1984 .

[43]  René Csuk,et al.  Aminoalkoholester von Hydroxyboranen, 10. Mitt. Tetracyclin‐Bor‐Mannich‐Basen als potentielle Antitumorwirkstoffe , 1984 .

[44]  A. Sarhan,et al.  Mannich Reaction with 5‐Phenylcyclohexan‐1,3‐dione , 1984 .

[45]  M. Schroeder,et al.  Organoselenium Chemistry. Preparation of Allyl and Homoallyl Amines by Aminomethylation of Phenylseleno‐Substituted Allyl Tin Reagents , 1984 .

[46]  K. Sloan,et al.  The aminomethylation of adenine, cytosine and guanine , 1984 .

[47]  J. Hodgkin.  New Mannich Base Ligands , 1984 .

[48]  H. Bestmann,et al.  N,N-Bis(trimethylsilyl)aminomethylation of Grignard Compounds — A Versatile Amine Synthesis , 1984 .

[49]  A. D. Gen,et al.  The synthesis of α‐amino‐substituted diphenylphosphine oxides , 1984 .

[50]  H. W. Reinhardt,et al.  Aminomethylierung von Enaminoestern , 1984 .

[51]  H. Griengl,et al.  Cyclische Aldehydderivate als Alkylierungsreagenzien, 2. Mitt. Aminoalkylderivate von 6‐Chlor‐ und 6‐Methylthiopurin und von Uracil , 1984 .

[52]  F. King.  A facile synthesis of quinolizidines and indolizidines , 1983 .

[53]  L. Pecci,et al.  Reaction of γ-carboxyglutamic acid with aldehydes , 1983 .

[54]  A. Onopchenko,et al.  Competing hydride transfer and ene reactions in the aminoalkylation of 1-alkenes with N,N-dimethylmethyleniminium ions. A literature correction , 1983 .

[55]  A. Caşcaval.  2-Hydroxyketones; XII1. A Simple Synthesis of 3,3,6,8-Tetrasubstituted 4-Chromanones , 1983 .

[56]  L. Overman,et al.  Synthesis applications of aza-Cope rearrangements. 11. Carbon-carbon bond formation under mild conditions via tandem cationic aza-Cope rearrangement-Mannich reactions. A convenient synthesis of polysubstituted pyrrolidines , 1983 .

[57]  P. Zeltner,et al.  1‐[(Dimethylamino)methyl]pyrrol aus Trimethyl (1‐pyrrolyl)‐ammonium‐Ion , 1983 .

[58]  P. Crooks,et al.  Reaction of 2‐acetamido‐3,7‐dihydropyrrolo[2,3‐d]pyrimidin‐4‐one with dimethylamine and formaldehyde. Formation of two isomeric mannich bases , 1983 .

[59]  R. Renaud,et al.  Synthesis of Mannich bases from electrochemically generated iminium salts in the presence of silyl enol ethers , 1983 .

[60]  D. Judd,et al.  A CONVENIENT SYNTHESIS OF MANNICH BASES OF THIOPHENE AND SUBSTITUTED THIOPHENES , 1983 .

[61]  M. L. Edwards,et al.  Mannich bases of 4-phenyl-3-buten-2-one: a new class of antiherpes agent. , 1983, Journal of medicinal chemistry.

[62]  T. Oida,et al.  The Reaction of O-Silylated Enolates of Carboxylic Esters and of Lactones with Aminomethyl Ethers Catalyzed by ZnCl2 , 1983 .

[63]  H. Möhrle,et al.  Über Hexahydrotriazine, 4. Mitt. Addition N‐monosubstituierter Amide an Azomethine , 1983 .

[64]  F. Eiden,et al.  2‐Aminomethyl‐3‐hydroxy‐1‐thiochromone; Darstellung und Reaktionen , 1983 .

[65]  R. G. Kostyanovsky,et al.  Macroheterocycles. XIV: A convenient synthesis of azacrown ether derivatives via aminomethylation , 1983 .

[66]  H. Adolph,et al.  Synthesis of polynitro- and nitronitrosoperhydro-1,5-diazocines , 1983 .

[67]  R. Ungaro,et al.  Selective Synthesis of Phenolic Mannich Bases under Solid-Liquid Phase Transfer Conditions , 1983 .

[68]  Kiyoshi Matsumoto,.  Synthesis under High Pressure: Mannich Reaction of Ketones and Esters with Dichloromethane and Secondary Amines , 1982 .

[69]  S. Danishefsky,et al.  An anomalous mannich reaction of a trimethylsilyl enol ether , 1982 .

[70]  T. Högberg,et al.  Allenes and Acetylenes. XXIV. Synthesis of alpha-Allenic Amines by Organocuprate Reactions of Acetylenic Aminoethers. , 1982 .

[71]  T. Higuchi,et al.  Kinetics and mechanism of hydrolysis of labile quaternary ammonium derivatives of tertiary amines. , 1982, Journal of pharmaceutical sciences.

[72]  G. Gevorgyan,et al.  Aminoacids as the Amine Component in the Mannich Reaction , 1982 .

[73]  A. Mori,et al.  Carbon-Carbon Bond Formation by the Use of Chloroiodomethane as a C1 Unit. IV. The Mannich Reaction of Ketones by Means of Dihalomethane and Secondary Amine , 1982 .

[74]  S. Miyano,et al.  Carbon-Carbon Bond Formation by the Use of Chloroiodomethane as a C1 Unit. III. A Convenient Synthesis of the Mannich Base from Enol Silyl Ether by a Combination of Chloroiodomethane and N,N,N′,N′-Tetramethylmethanediamine , 1982 .

[75]  E. S. Binkley,et al.  Total synthesis of lycopodium alkaloids: (.+-.)-lycopodine, (.+-.)-lycodine, and (.+-.)-lycodoline , 1982 .

[76]  H. Möhrle,et al.  Über Mannichbasen, 17. Mitt. Amino‐ und Amidoalkylierung von 2‐Methylnaphthol bzw. 1‐Naphthol , 1982 .

[77]  H. Möhrle,et al.  Über Mannichbasen, 19. Mitt. Mannich‐Reaktionen mit 1‐Naphthol und primären Aminen , 1982 .

[78]  H. Möhrle,et al.  Über Mannichbasen, 18. Mitt. Mannichreaktionen mit 1‐Naphthol und sekundären Aminen , 1982 .

[79]  A. Hosomi,et al.  A novel aminomethylation of silyl enol ethers with aminomethyl ethers catalyzed by iodotrimethylsilane or trimethylsilyl trifluoromethanesulfonate , 1982 .

[80]  H. W. Reinhardt,et al.  Aminomethylierung von push‐pull‐Olefinen , 1982 .

[81]  C. Wermuth,et al.  Lactone chemistry. Synthesis of .beta.-substituted, .gamma.-functionalized butan- and butenolides and succinaldehydic acids from glyoxylic acid , 1981 .

[82]  A. Calcagni,et al.  α-Hydroxymethylation of Schiff Bases Derived from α-Amino Acid Esters , 1981 .

[83]  J. Polazzi.  Mannich reaction product of dihydrocodeinone , 1981 .

[84]  R. T. Buckler,et al.  Antimicrobial 3-methyleneflavanones. , 1981, Journal of medicinal chemistry.

[85]  T. J. Delia,et al.  Synthesis of 6-benzyl- and 6-phenethyl-2,4-diamino-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidines† , 1981 .

[86]  P. Bansal,et al.  N-hydroxymethyl derivatives of nitrogen heterocycles as possible prodrugs I: N-hydroxymethylation of uracils. , 1981, Journal of pharmaceutical sciences.

[87]  A. Yoshitake,et al.  Labelling of neuroleptic butyrophenones. III. Synthesis of 2′-amino-4′-fluoro-4-[4-hydroxy-4-(3-trifluoromethylphenyl)piperidino-2-14C] - butyrophenone , 1981 .

[88]  M. Genies,et al.  Utilisation en synthese du cation iminium genere in situ par oxydation electrochimique d'amines tertiaires , 1981 .

[89]  H. Möhrle,et al.  Über Mannichbasen, 15. Mitt. Reaktion von Hexamethylentetramin mit 1‐Naphthol und 2‐bzw. 4‐substituierten Derivaten , 1981 .

[90]  H. W. Reinhardt,et al.  Aminoalkylierung von Enaminoketonen , 1981 .

[91]  N. Goff,et al.  Synthesis of conjugated triene-diamines through the isomerization of αω-diaminononadiynes , 1981 .

[92]  A. Alexakis,et al.  CARBOMETALATION (C-METALATION) OF ALKYNES: STEREOSPECIFIC SYNTHESIS OF ALKENYL DERIVATIVES , 1982 .

[93]  H. Scharf,et al.  Synthese von 3(2H)-Furanonen und 3-Methoxyfuranen , 1981 .

[94]  A. Alexakis,et al.  Vinyl-copper derivatives. XII. Stereospecific synthesis of allylic amines by aminomethylation of organocopper reagents , 1981 .

[95]  P. Gayral,et al.  Chemical study and anti-parasitic activity of iminobarbituric derivatives. , 1981 .

[96]  S. Phillips,et al.  QUINO(1,2‐C)QUINAZOLINES. I. SYNTHESIS OF QUINO(1,2‐C)QUINAZOLINIUM DERIVATIVES AND THE RELATED INDAZOLO(2,3‐A)QUINOLINE DERIVATIVES AS ANALOGS OF THE ANTITUMOR BENZO(C)PHENANTHRIDINE ALKALOIDS , 1980 .

[97]  C. Melchiorre,et al.  Reductive opening of the thiazolidine ring. Selective N‐methylation of cysteamines , 1980 .

[98]  J. Coyle,et al.  Synthesis of 2,4-Benzodiazepines from Phthalimide Mannich Bases , 1980 .

[99]  Y. Kita,et al.  SYNTHESIS OF 1-SUBSTITUTED 3-ANILINO-4-DIETHYLAMINOMETHYL-5-OXO-3,4-DEHYDROPIPERIDINES AND 2-SUBSTITUTED 1,2,3,5,6,11-HEXAHYDRO-5-PHENYL-4H-PYRIDO(3,4-B)(1,5)BENZODIAZEPIN-4-ONES , 1980 .

[100]  J. Jiricny,et al.  Reactions between ribonucleoside derivatives and formaldehyde in ethanol solution , 1980 .

[101]  K. Balasubramanian,et al.  Studies on o-Quinonemethides; Part IV. Alkylation of Phenolic Mannich Bases with Aryl Phenacyl Sulfones , 1980 .

[102]  J. Plattner,et al.  Neuroleptic activity in 5-aryltetrahydro-gamma-carbolines. , 1980, Journal of medicinal chemistry.

[103]  A. Sartorelli,et al.  Synthesis and antineoplastic activity of hydroquinone dialdehydes. , 1980, Journal of medicinal chemistry.

[104]  H. Yamanaka,et al.  Studies on Pyrimidine Derivatives. XVIII. Reaction of Active Methyl Groups on Pyrimidine N-Oxides , 1980 .

[105]  B. Roth,et al.  2,4-Diamino-5-benzylpyrimidines as antibacterial agents. 4. 6-Substituted trimethoprim derivatives from phenolic Mannich intermediates. Application to the synthesis of trimethoprim and 3,5-dialkylbenzyl analogues. , 1980, Journal of medicinal chemistry.

[106]  T. Bryson,et al.  Performed Mannich salts: a facile preparation of dimethyl(methylene)ammonium iodide , 1980 .

[107]  B. Herman,et al.  Synthesis of a conjugated triene diamine [1,2-bis(β-dimethylaminovinyl)cyclopentene] through the isomerization of an αω-diaminonadiyne , 1980 .

[108]  F. Hénin,et al.  An Easy Transformation of Ketones into α,α-Epoxymethylketones by Hydrogen Peroxide Oxidation of Mannich Base Derivates , 1980 .

[109]  S. Danishefsky,et al.  Regioselective mannich reactions via trimethylsilyl enol ethers , 1980 .

[110]  C. Schoerner,et al.  1.5-Diaza-3.7-diphospha-cyclooctane , 1980 .

[111]  H. Möhrle,et al.  Über Hexahydrotriazine, 3. Mitt. Mannichreagenzien aus 1,3,5‐Trialkylhexahydro‐1,3,5‐triazinen , 1980 .

[112]  K. Undheim,et al.  1H-2-BENZOTHIOPYRAN-4(3H)-ONE IN ALDOL AND MANNICH REACTIONS , 1980 .

[113]  J. Craig,et al.  Novel rearrangement of prop-2-ynyl N-Oxides to hydroxylamine O-allenyl ethers: mechanistic studies , 1980 .

[114]  Daniel M. Brown,et al.  Electrophilic substitution in dihydrouracils , 1979 .

[115]  G. Pettit,et al.  Antineoplastic agents LXIV: 1,4-Bis(2'-chloroethyl)-1,4-diazabicyclo[2.2.1]heptane dihydrogen dimaleate. , 1979, Journal of pharmaceutical sciences.

[116]  J. Hester,et al.  New synthesis of 8-chloro-1-[2-(dimethylamino)ethyl]-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine, which has antidepressant properties , 1979 .

[117]  J. Dimmock,et al.  Syntheses and bioactivities of 1-(hydroxyphenyl)-1-nonen-3-ones and related ethers and esters. , 1979, Journal of pharmaceutical sciences.

[118]  I. Omae.  Organometallic intramolecular-coordination compounds containing a nitrogen donor ligand , 1979 .

[119]  J. Dimmock,et al.  Nuclear-substituted styryl ketone analogs: effects on neoplasms, microorganisms, and mitochondrial respiration of tumorous and normal cells. , 1979, Journal of pharmaceutical sciences.

[120]  F. Montanari,et al.  Synthesis of α-Aminoarylacetic Acids from Chloroform, Arylaldehydes, and Aqueous Ammonia under Two-Phase Conditions , 1979 .

[121]  C. McDonald,et al.  The Mannich Reaction of Poly(acrylamide) , 1979 .

[122]  E. S. Turner,et al.  Conformational equilibria and nitrogen inversion in tetrahydro-1,2,5-oxadiazines , 1979 .

[123]  W. Granitzer,et al.  Stereoselective trans-reduktion tert. Propargylamine mit DIBAH zu (E)-Allylaminen , 1979 .

[124]  H. Möhrle,et al.  Aminomethylierung N‐monosubstituierter vinyloger Formamide , 1979 .

[125]  I. Murata,et al.  A novel coupling reactiong of 1-azylylmethyltrimethylammonium iodide. Synthesis of 1,2-bis[1-azulyl)ethane and [2.2.2.2](1,3)azulenophane , 1979 .

[126]  N. Holy,et al.  The mannich reaction-II : Derivatization of aldehydes and ketones using dimethyl(methylene)ammonium salts , 1979 .

[127]  E. S. Binkley,et al.  A highly efficient total synthesis of (.+-.)-lycopodine , 1978 .

[128]  J. Dimmock,et al.  Synthesis of oximes, aziridines, and allyl alcohols derived from substituted 1-phenyl-1-nonen-3-ones as potential cytotoxic and antitumor agents. , 1978, Journal of pharmaceutical sciences.

[129]  J. Dimmock,et al.  Synthesis and evaluation of 1-(hydroxyphenyl)-1-nonen-3-ones and related compounds for antineoplastic and antimicrobial activities. , 1978, Journal of pharmaceutical sciences.

[130]  H. Rapoport,et al.  Stereospecific cyclizations of iminium salts from .alpha.-amino acid decarbonylation. Synthesis of 8- and 13-methylberbines , 1978 .

[131]  J. Bobbitt,et al.  SYNTHESES OF INDOLES AND CARBOLINES VIA AMINOACETALDEHYDE ACETALS , 1978 .

[132]  M. Neumann,et al.  Reaction of sodium hydroxymethanesulfonate with substituted anilines. , 1978, Journal of pharmaceutical sciences.

[133]  H. Zoorob,et al.  Reactivity of 4‐hydroxy‐2‐methyl‐7,8,9,10‐tetrahydrobenzo[h] quinoline towards base‐catalyzed cyclization, mannich and turpin reactions , 1978 .

[134]  M. Nanasawa,et al.  Syntheses of Aromatic Mannich Bases Involving Nitrogen Heterocycles by Means of Amine-exchange Reaction , 1978 .

[135]  A. Tzschach,et al.  Organoarsen-verbindungen: XXXIII. Synthese und reaktionsverhalten der α-aminomethylphosphine und -arsine☆ , 1978 .

[136]  D. Hansell.  Mannich Reaction of 2,5‐Xylenol, Morpholine and Formaldehyde , 1978 .

[137]  D. Redmore.  N-benzyl-.alpha.-aminophosphonic acids , 1978 .

[138]  D. Redmore.  Chemistry of phosphorous acid: new routes to phosphonic acids and phosphate esters , 1978 .

[139]  J. Burckhalter,et al.  Synthesis of pyrimido[5,4-c]quinolines and related quinolines as potential antimalarials. , 1978, Journal of medicinal chemistry.

[140]  J. Dimmock,et al.  Synthesis of diastereoisomeric 4-dimethylamino-3-phenyl-2-butanols and related esters for antimicrobial evaluation. , 1978, Journal of pharmaceutical sciences.

[141]  M. Lucas,et al.  Induction asymetrique—II: Determination des configurations relatives de δ-amino β-hydroxyesters diastereoisomeres, obtenus par la reaction de reformatsky , 1978 .

[142]  H. J. Roth,et al.  Versuche zur Synthese von pharmakologisch wirksamen Heterocyclen via Mannich‐Reaktion, 4. Mitt. Cycloalka[g]‐ und Benzocycloalka[g] pyrido[2,3‐d] pyrimidindione , 1978 .

[143]  G. Stork,et al.  N,N-diethylaminoacetonitrile a generally useful latent acyl carbanion , 1978 .

[144]  H. J. Roth,et al.  Versuche zur Synthese von pharmakologisch wirksamen Heterocyclen via Mannich‐Reaktion, 3. Mitt. Pyrido[2,3‐d] pyrimidin‐2,4‐dione (5‐Desazapteridine) , 1978 .

[145]  H. J. Roth,et al.  Versuche zur Synthese pharmakologisch wirksamer Heterocyclen via Mannich Reaktion, 2. Mitt. Partiell hydrierte Benzocycloalkeno[b] chinolinone , 1978 .

[146]  Koichiro Yamada,et al.  ‘One-pot’ conversion of mannich bases via quaternary ammonium salts into the corresponding methyl compounds with sodium cyanoborohydride in hexamethylphosphoramide , 1978 .

[147]  B. Unterhalt,et al.  Substituierte 1,2,4,6‐Thiatriazacyclohexan‐1,1‐dioxide , 1978 .

[148]  H. J. Roth,et al.  Synthese polyfunktioneller Heterocyclen durch Aminoalkylierung von Nitroalkanen , 1978 .

[149]  M. Lucas,et al.  Induction asymétrique—IV: Etude des modes de reconnaissance intermoléculaire des β-aminocétones aromatiques prochirales, par les réactifs de réformatsky. Mise en évidence d'un phénoméne de participation , 1978 .

[150]  U. Kuckländer.  Mannich‐Basen von 6‐Hydroxy‐indol‐Derivaten , 1978 .

[151]  Hideo Tanaka,et al.  Preparation of Mannich Bases from 6-Methoxy-2H-pyran-3(6H)-one and Its Epoxide , 1977 .

[152]  J. W. Phillips,et al.  New compounds: organoboron derivatives of tetracyclines I: synthesis of carboxamido derivative of tetracycline with perhydro-2-phenyl-1,3,6,2-dioxazaborocine. , 1977, Journal of pharmaceutical sciences.

[153]  H. Chiang,et al.  Total synthesis of (+/-)-discretamine and (+/-)-stepholidine. , 1977, The Journal of organic chemistry.

[154]  R. Noyori,et al.  Synthesis of 3(2H)-Furanones by the Iron Carbonyl-promoted Cyclocoupling Reaction of α,α′-Dibromo Ketones and Carboxamides. A Convenient Route to Muscarines , 1977 .

[155]  T. Kitahara,et al.  The total synthesis of dl-vernolepin and dl-vernomenin , 1977 .

[156]  J. Fowler.  2-Methyl-3-butyn-2-ol as an acetylene precursor in the Mannich reaction. A new synthesis of suicide inactivators of monoamine oxidase. , 1977, The Journal of organic chemistry.

[157]  Y. Maki,et al.  A Mannich-Type Cyclisation to Thiazepines. Synthesis of Pyrimido[5,4-f]benzo[b]-1,4-thiazepines, a New Tricyclic System , 1977 .

[158]  H. Stetter,et al.  Addition von Aldehyden an aktivierte Doppelbindungen, XIV. Über die katalysierte Reaktion von Aldehyden mit Mannich‐Basen , 1977 .

[159]  J. Hodgkin,et al.  Cyclopolymerization. XIII. Cyclopolymerization of Diallylaminomethylphenols , 1977 .

[160]  M. Sekiya,et al.  N-[(N-Nitrosoarylamino) methyl] succinimide as a New Agent Generating Aromatic Diazotate , 1977 .

[161]  F. Seela,et al.  Mannich‐Reaktion am 2‐Amino‐3,7‐dihydropyrrolo[2,3‐d]‐pyrimidin‐4‐on, dem Chromophor des Ribonucleosids „Q”︁ , 1977 .

[162]  S. Brookman,et al.  Synthetic acetylenic antifungal agents. , 1977, Journal of pharmaceutical sciences.

[163]  N. Holy,et al.  New applications of the Mannich reaction. Use of dimethyl(methylene)ammonium trifluoroacetate for regiospecific carbanion quenching. A new route to .alpha.-methylene-.gamma.-butyrolactone , 1977 .

[164]  C. Poulter,et al.  Addition of eschenmoser's salt to ketone, ester, & lactone enolates. A convenient synthesis of a-methylene carbonyls via mannich intermediates☆ , 1977 .

[165]  P. Messinger,et al.  Sulfone als chemische Transportformen germicid wirkender Stoffe, 8. Mitt. Sulfonylderivate von Chinaldin‐, Pyrrol‐ und Phenol‐Mannichbasen , 1977 .

[166]  R. R. Schumaker,et al.  Methylthioformaldine. A new formaldehyde anion equivalent , 1977 .

[167]  H. Böhme,et al.  Zur Acylspaltung von Formaldehyd‐N,O‐acetalen , 1977 .

[168]  A. Marquet,et al.  Synthese regioselective de bases de mannich de cetones dissymetriques , 1977 .

[169]  P. Messinger,et al.  Cyclische Sulfone aus Mannich‐Basen und Natrium‐hydroxymethan‐sulfinat , 1977 .

[170]  P. Messinger,et al.  Synthese symmetrischer Sulfone aus Natrium-hydroxymethansulfinat und Mannichbasen , 1977 .

[171]  R. Mornet,et al.  Synthese de l'acetate du chloro-4 methyl-2 butene-2 ol-1 (E.) Nouvelle voie d'acess a la trans-zeatine. , 1977 .

[172]  B. Unterhalt,et al.  Styrylalkyloxime; XV1. Sauerstoff-Mannich-Basen , 1977 .

[173]  J. Lamberton,et al.  The reaction of formaldehyde with mixtures of arylhydrazines and amines , 1976 .

[174]  A. Katritzky,et al.  THE CONFORMATIONAL ANALYSIS OF SATURATED HETEROCYCLES. 77. RATIONALIZATION OF F THE EQUILIBRIUMS OF TETRAALKYLHEXAHYDRO-1,2,4,5-TETRAZINES , 1976 .

[175]  R. Kallen,et al.  Equilibria and kinetics of N-hydroxymethylamine formation from aromatic exocyclic amines and formaldehyde. Effects of nucleophilicity and catalyst strength upon mechanisms of catalysis of carbinolamine formation¹. , 1976, Journal of the American Chemical Society.

[176]  D. Cameron,et al.  Some piperidinomethyl quinols and quinones , 1976 .

[177]  T. Kitahara,et al.  Reactions of silyl enol ethers and lactone enolates with dimethyl(methylene)ammonium iodide. The bis-.alpha.-methylenation of pre-vernolepin and pre-vernomenin , 1976 .

[178]  L. Tietze,et al.  A New Variant of the Mannich Reaction , 1976 .

[179]  M. Sekiya,et al.  A New Convenient Synthesis of Diazoalkanes from N-[(N-Nitrosoalkylamino) methyl] benzamides , 1976 .

[180]  E. Schreier.  Radiolabelled Peptide Ergot Alkaloids. 83. Mitteilung über Mutterkornalkaloide , 1976 .

[181]  D. Berney,et al.  1‐aralkylated tetrahydro‐2‐benzazepines. Part II: Synthesis from 3‐(3,4‐dimethoxyphenyl)‐propylamine , 1976 .

[182]  A. Schmidt,et al.  p‐Hydroxybenzylierung von Carbanionen mit Chinonmethid‐liefernden Verbindungen , 1976 .

[183]  H. Möhrle,et al.  Über Mannichbasen, XII: Hydroxylaminomethylierung von 2‐Naphthol , 1976 .

[184]  F. Kröhnke.  The Specific Synthesis of Pyridines and Oligopyridines1 , 1976 .

[185]  M. R. Snow,et al.  Condensation of formaldehyde with chelated glycine and ethylenediamine: a new macrocycle synthesis; X-ray structures of [α-hydroxymethylserine-bis(ethylenediamine)cobalt(III)]2+ and [α-hydroxymethylserine-1,4,8,11-tetra-aza-6,13-dioxacyclotetradecanecobalt(III)]2+ ions , 1976 .

[186]  H. J. Roth,et al.  Versuche zur photochemischen Synthese ephedrin‐ähnlicher Verbindungen; II. Photodehydrierung von 3‐Alkylamino‐propiophenonen , 1976 .

[187]  W. Werner.  Kondensation von 2‐Hydroxy‐acetophenon‐Derivaten zu Mannichbasen des Chromanon‐(4) , 1976 .

[188]  J. Dimmock,et al.  Comparison of antimicrobial activity of nuclear-substituted aromatic esters of 5-dimethylamino-1-phenyl-3-pentanol and 3-dimethylamino-1-phenyl-1-propanol with related cyclic analogs. , 1976, Journal of pharmaceutical sciences.

[189]  B. Shaw,et al.  Transition metalcarbon bonds: XL. Palladium(II) complexes of [(dimethylamino)methyl]-ferrocene , 1975 .

[190]  G. Zinner,et al.  Aminomethylierung von N‐Hydroxyphthalimid, II1) , 1975 .

[191]  L. Goodman,et al.  Imidazo[1,5-a]pyrazines. IV. Aromatic substitution reactions , 1975 .

[192]  J. Short,et al.  The use of amino acids in the mannich reaction , 1975 .

[193]  R. Opitz,et al.  Correspondence between theoretically predicted and experimentally observed sites of electrophilic substitution on a fused-tricyclic heteroaromatic (azulene) system , 1975 .

[194]  J. M. Barker,et al.  Mannich Reactions of Methoxythiophens , 1975 .

[195]  S. A. Metwally,et al.  Anthrachinone, VI. Hydroxymethylierung und Aminomethylierung von Anthrachinonen , 1975 .

[196]  D. Schwarz,et al.  Photoreaktionen von Bis‐phthalimidomethyl‐alkylaminen , 1975 .

[197]  S. Inoue,et al.  The Mannich Reaction of Alicyclic α-Diketones. A Novel Synthesis of 2-Hydroxy-3-methyl-2-cyclohexen-1-one , 1975 .

[198]  M. Tanno,et al.  The Mannich Reaction of 3,6-Dimethyl-5-hydroxypyridazine 1-Oxide , 1975 .

[199]  L. Gouin,et al.  L'addition des organomagnesiens aliphatiques satures sur les triples liaisons disubstituees non conjuguees , 1975 .

[200]  R. Mornet,et al.  L'addition des organomagnesiens aliphatiques satures sur les triples liaisons disubstituees non conjuguees I. Cas des alcoxy-1 amino-4 butynes-2 , 1975 .

[201]  L. Guggenberger,et al.  An unusual stereospecific reduction of some basic side-chain substituted indoles. , 1975 .

[202]  K. Nagarajan,et al.  A novel transformation of 6,7-dimethoxy- and 6,7-methylene-dioxy-1-(2-bromo-4,5-methylenedioxy-α-methyl) benzyl-1,2,3,4-tetrahydroisoquinolines to benzoxazepinoisoquinolines , 1975 .

[203]  H. Gross,et al.  α‐Substituierte Phosphonate, XVIII. Mono‐ und Bisphosphono‐Derivate des 2.6‐Di‐tert.‐butyl‐p‐kresols , 1975 .

[204]  U. Rehse.  Mannichbasen aus β‐Dicarbonylverbindungen , 1975 .

[205]  D. Schwarz,et al.  Photocyclisierung von Phthalimid‐Mannichbasen , 1975 .

[206]  N. Hayashi,et al.  Synthesis of 3-morpholino-N-ethoxycarbonyl sydnonimine-5-14C (sin-10-14C) , 1975 .

[207]  S. Vogel,et al.  [Synthesis of Mannich bases of imidazolidine-2-thione]. , 1975, Acta poloniae pharmaceutica.

[208]  H. Stetter,et al.  Kondensationen mit Methylendisulfonen , 1974 .

[209]  R. Jones,et al.  Synthesis of cyclopentano-1,2,3,4-tetrahydroisoquinolines. Novel heterocyclic systems , 1974 .

[210]  W. Bock,et al.  Hydroxylamine in der Vierkomponenten‐Kondensation nach Ugi, II , 1974 .

[211]  S. Martin,et al.  Facile method for the transformation of ketones into .alpha.-substituted aldehydes , 1974 .

[212]  G. Pettit,et al.  Antineoplastic agents. 36. Acetylenic carrier groups. , 1974, Journal of medicinal chemistry.

[213]  D. Daigle,et al.  Synthesis of a monophosphorus analog of hexamethylenetetramine , 1974 .

[214]  A. Sartorelli,et al.  Potential bioreductive alkylating agents. 3. Synthesis and antineoplastic activity of acetoxymethyl and corresponding ethyl carbamate derivatives of benzoquinones. , 1974, Journal of medicinal chemistry.

[215]  T. Chen,et al.  Letter: Enhancement of optical rotation of levodopa by cyclization. , 1974, Journal of pharmaceutical sciences.

[216]  K. Balasubramanian,et al.  Robinson-Mannich annelation of cyclohexane-1,3-dione , 1974 .

[217]  F. Eiden,et al.  Untersuchungen an 4‐Pyronen, 51 Aminoalkylierung von Chromonen , 1974 .

[218]  B. Kamieński.  The di-(2-alkyl-2-nitroethyl)-methylamines from reactions of nitroalkanes with formaldehyde and methylamine , 1974 .

[219]  H. Böhme,et al.  Zur Aminomethylierung von 1‐Cyan‐isochroman und 1‐Cyan‐isothio‐chroman. 16. Mitt. über Untersuchungen in der Isochroman‐ und Isothiochroman‐Reihe, zugleich 46. Mitt. über α‐halogenierte Amine , 1974 .

[220]  T. Urbański.  Primary Nitro Compounds as a Source of some Heterocyclic Systems , 1974 .

[221]  R. Coombs,et al.  The Preparation of α-Allenic Alcohols; Acetylene → Allene "Homologization" , 1974 .

[222]  P. Messinger,et al.  Notiz zur Synthese von α‐Amino‐ und α‐Amidosulfonen. 5. Mitt. über Sulfone als chemische Transportformen germicid wirkender Stoffe , 1974 .

[223]  J. V. Greenhill,et al.  A base exchange reaction between a 1,2-diketo-bis mannich base and O-phenylenediamine , 1974 .

[224]  J. Vierfond,et al.  [Selective aminomethylation in the N-propargylaniline series]. , 1973, Annales pharmaceutiques francaises.

[225]  S. Nozoe,et al.  Application of the Mannich Reaction to 1-Azaazulan-2-one. Syntheses of Seven-Membered Analogues of Tryptophan and Related Compounds , 1973 .

[226]  H. Böhme,et al.  Über α‐halogenierte Amine, XLV. Zur Aminomethylierung von (2‐Chloräthyl)hydrazinen und Chloressigsäure‐hydraziden , 1973 .

[227]  Peter Y. Johnson,et al.  Mannich reaction. 6-Alkoxytetrahydro-5,5-dimethyl-1,3-oxazines , 1973 .

[228]  Z. Janousek,et al.  The Chemistry of Dichloromethylenammonium Salts (“Phosgenimonium Salts”) , 1973 .

[229]  K. Leander,et al.  THE CHEMISTRY OF HEXAHYDRO-1,2,4,5-TETRAZINES PART 4, THE REACTIONS OF ALKYLHYDRAZINES WITH FORMALDEHYDE , 1973 .

[230]  E. Mutschler,et al.  [Reduction of Mannich bases of monoacyl-biphenyl compounds. 2. Potential analgesics]. , 1973, Archiv der Pharmazie.

[231]  D. Korbonits,et al.  Mannich-type reactions of an isobasic isoquinoline† , 1973 .

[232]  P. Messinger.  [Sulfones via Mannich bases. 2. Sulfones as chemical transport forms of germicidally active substances]. , 1973, Archiv der Pharmazie.

[233]  S. Kamiya,et al.  Syntheses of 3- and 4-Alkylaminomethylpyridazines , 1973 .

[234]  H. Möhrle,et al.  [Mannich bases of 2,6-disubstituted phenols. VI (author's transl)]. , 1973, Archiv der Pharmazie.

[235]  M. Yamauchi,et al.  A Novel Mannich Reaction Product from 2, 4 (5)-Diisopropylimidazole , 1973 .

[236]  K. Harada,et al.  Sterically Controlled Syntheses of Optically Active Organic Compounds. XIX. Asymmetric Syntheses of Amino Acids by the Strecker Reaction , 1973 .

[237]  T. Kametani,et al.  [Studies on the syntheses of heterocyclic compounds. DXVII. Syntheses of berberine and related compounds. II. The Mannich reaction of 1-benzylisoquinoline under various conditions]. , 1973, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

[238]  S. M. A. D. Zayed,et al.  Aminomethylierung von (Arylthio)‐ und (Arylsulfonyl)‐acethydroxamsäuren , 1973 .

[239]  Barbara F. Smith,et al.  Synthesis of α-Methylenecarbonyl Compounds: An Unexpected Product from the Mannich Reaction On 2-Carbomethoxycyclohexanone , 1973 .

[240]  P. Messinger.  Anlagerung von Sulfinsäuren an aktivierte Alkene. 1. Mitt. über Sulfone als chemische Transportformen germicid wirkender Stoffe , 1973 .

[241]  H. Stetter,et al.  A New Method for Addition of Aldehydes to Activated Double Bonds , 1973 .

[242]  J. Bridson,et al.  Method for the regiospecific synthesis of Mannich bases. Reaction of enol borinates with dimethyl(methylene)ammonium iodide , 1973 .

[243]  M. Tramontini.  Advances in the Chemistry of Mannich Bases , 1973 .

[244]  B. Unterhalt,et al.  Nitramine; IV1. Aminomethyl-nitramine , 1973 .

[245]  L. Miginiac,et al.  Étude de l'addition des organozinciques α-éthyléniques aux amines éthyléniques, acétyléniques et alléniques , 1972 .

[246]  U. Thewalt,et al.  Röntgenographische Charakterisierung des Reaktionsproduktes von Bis(S‐amino‐dithionitrito)‐nickel(II) mit Ammoniak, Formaldehyd und Methanol , 1972 .

[247]  M. Sauerbier,et al.  Bis‐acetylenketone, Übergangsmetallkomplexe und deren reaktives Verhalten, XII. Synthesen von Chinonen , 1972 .

[248]  A. Tzschach,et al.  Arsenorgano‐Verbindungen. XIX. Umsetzungen von MANNICH‐Basen mit sekundären Phosphinen und Arsinen , 1972 .

[249]  H. Möhrle,et al.  Nachbargruppeneffekt von phenolen , 1971 .

[250]  R. Kallen.  The mechanism of reactions involving Schiff base intermediates. Thiazolidine formation from L-cysteine and formaldehyde. , 1971, Journal of the American Chemical Society.

[251]  H. Volz,et al.  Methylenimmoniumsalze durch Hydrid‐Abstraktion aus tertiären Aminen , 1971 .

[252]  D. D. Reynolds,et al.  1,3,5‐Trisubstituted hexahy drotriazines as mannich reagents. I. Preparation of secondary aminomethyl sulfide hydrochlorides , 1971 .

[253]  D. D. Reynolds,et al.  1,3,5-Trisubstituted hexahydrotriazines as mannich reagents. III. Preparation and cleavage of 3,4-dihydro-6-hydroxy-3-substituted-2H-1,3-benzoxazine hydrochlorides , 1971 .

[254]  D. D. Reynolds,et al.  1,3,5‐Trisubstituted hexahydrotriazines as mannich reagents. II. Preparation of p‐secondary aminomethylphenols , 1971 .

[255]  A. Eschenmoser,et al.  Dimethyl(methylene)ammonium Iodide , 1971 .

[256]  W. Kliegel,et al.  Zur Aminomethylierung von N‐Hydroxy‐phthalimid , 1971 .

[257]  H. Dorn,et al.  Potentielle Cytostatica. XX. Bis‐(2‐chlor‐äthyl)‐aminomethyl‐pyrazol‐Derivate , 1971 .

[258]  G. A. Swan.  Studies on the reaction of benzoyl peroxide with NN-disubstituted aromatic amines and related compounds. Part V. Preparation of 5,11-disubstituted 5,6,11,12-tetrahydrophenhomazines from α-diamines , 1971 .

[259]  N. Kreutzkamp,et al.  Über die Umsetzung von Schwefelkohlenstoff mit Mannich‐Basen , 1971 .

[260]  H. G. Richey,et al.  Promotion by primary and tertiary amine functions of additions of grignard reagents to alkenes and alkynes , 1971 .

[261]  H. Dorn,et al.  Dehydrierung 1-substituierter Pyrazolidone-(3) in Gegenwart von Formaldehyd und sekundären Aminen , 1971 .

[262]  F. Scott,et al.  Mechanism of pyrazoline formation from the reactions of substituted hydrazines and Mannich bases , 1971 .

[263]  Y. Shiokawa,et al.  Studies on Benzimidazoles and Related Compounds. III. The Intramolecular Mannich Reaction of 2-Alkylaminomethylbenzimidazoles , 1970 .

[264]  F. Scott,et al.  The mechanism of pyrazoline formation. I. 1-amidinopyrazolines. , 1970 .

[265]  Hams KrieGer,et al.  Auftreten eines aldehyds und seiner folgeprodukte bei der aminomethylierung eines bicyclischen alkens , 1966 .