Conformal NMR spectroscopy: Accurate localization to noncuboidal volumes with optimum SNR

“Conformal Spectroscopy” is a general method for the acquisition of accurately localized NMR spectra from noncuboidal regions with optimum signal‐to‐noise ratio (SNR). The method is based upon the localization of volumes defined by a number of intersecting oblique slices and may be implemented using standard imager hardware. Conformal techniques can enhance many existing localization sequences such as ISIS (31P) and STEAM (1H) resulting in typical SNR improvements of around 1.8, equivalent to a more than threefold reduction in acquisition time. Applications include in vivo tumor Spectroscopy.

[1]  L. Hall,et al.  VOISINER, a new method for spatially resolved NMR spectroscopy , 1988 .

[2]  R. Ordidge,et al.  A general approach to selection of multiple cubic volume elements using the ISIS technique , 1988, Magnetic resonance in medicine.

[3]  John S. Leigh,et al.  Hadamard spectroscopic imaging (HSI) for multivolume localization , 1988 .

[4]  A. Benabid,et al.  Symmetric pulses for spatially resolved spectroscopy , 1988 .

[5]  Roger J. Ordidge,et al.  Outer volume suppressed image related in vivo spectroscopy (OSIRIS), a high-sensitivity localization technique , 1988 .

[6]  H C Charles,et al.  Human in vivo phosphate metabolite imaging with 31P NMR , 1988, Magnetic resonance in medicine.

[7]  A. S. Hall,et al.  In vivo implementation of three-dimensional phase-encoded spectroscopy with a correction for field inhomogeneity , 1988 .

[8]  S. Müller,et al.  Multifrequency selective rf pulses for multislice MR imaging , 1988, Magnetic resonance in medicine.

[9]  A. Volk,et al.  High-resolution localized spectroscopy at 4.7 Tesla by frequency-interval-selective volume localization (FRIVOL) , 1988 .

[10]  R. Sauter,et al.  Multivolume selective spectroscopy , 1988 .

[11]  D. Flamig,et al.  The SWIFT method for in vivo localized excitation (SMILE) , 1987 .

[12]  D. Doddrell,et al.  Low‐power NMR volume selection by slicing z magnetization , 1987, Magnetic resonance in medicine.

[13]  Jens Frahm,et al.  Localized proton spectroscopy using stimulated echoes. , 1987 .

[14]  R. Kimmich,et al.  Volume-selective multipulse spin-echo spectroscopy , 1987 .

[15]  Joseph Granot,et al.  Selected Volume Excitation Using Stimulated Echoes (VEST). Applications to spatially localized spectroscopy and imaging , 1986 .

[16]  A Haase,et al.  Localization of unaffected spins in NMR imaging and spectroscopy (LOCUS spectroscopy) , 1986, Magnetic resonance in medicine.

[17]  D. Doddrell,et al.  Discrete isolation from gradient-governed elimination of resonances. DIGGER, a new technique for in vivo volume-selected NMR spectroscopy , 1986 .

[18]  W. Edelstein,et al.  The intrinsic signal‐to‐noise ratio in NMR imaging , 1986, Magnetic resonance in medicine.

[19]  Andrew A. Maudsley,et al.  Sensitivity in fourier imaging , 1986 .

[20]  D. Doddrell,et al.  Spatial and chemical-shift-encoded excitation. SPACE, a new technique for volume-selected NMR spectroscopy , 1986 .

[21]  David T. Pegg,et al.  Uniform sample excitation with surface coils for in vivo spectroscopy by adiabatic rapid half passage , 1986 .

[22]  P. Luyten,et al.  Solvent-suppressed spatially resolved spectroscopy. An approach to high-resolution NMR on a whole-body MR system , 1986 .

[23]  Roger J. Ordidge,et al.  Image-selected in Vivo spectroscopy (ISIS). A new technique for spatially selective nmr spectroscopy , 1986 .

[24]  J. Granot.  Selected volume spectroscopy (SVS) and chemical-shift imaging. A comparison , 1986 .

[25]  W. Aue,et al.  Practical aspects of volume-selective excitation (VSE). Compensation sequences , 1985 .

[26]  M. S. Silver,et al.  Highly selective {π}/{2} and π pulse generation , 1984 .