On the Amazing Olivocerebellar System

Abstract: Over the last four decades elegant sets of a single‐cell studies, originating from various research groups, have contributed significantly to our understanding of olivary and cerebellar physiology. Nevertheless questions relating to the dynamic properties of olivocerebellar network, as a system, remain unsolved. We may be reaching the limits of what can be learned using the single‐cell recordings. Further research on this subject may require study of the spatiotemporal activity profiles of ensemble neuronal activity. This paper summarizes results obtained using voltage‐sensitive dye imaging in inferior olive slices, and the use of mathematical modeling to address such activity profiles.

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