Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
暂无分享,去创建一个
A. Regev | L. Tsai | Jennie Z. Young | M. Hemberg | P. D. De Jager | R. Ransohoff | Hansruedi Mathys | Fan Gao | C. Adaikkan | Elodie Manet | Chinnakkaruppan Adaikkan
[1] Michael J. Grusby,et al. Absence of MHC class ii molecules reduces CNS demyelination, microglial/macrophage infiltration, and twitching in murine globoid cell leukodystrophy , 1994, Cell.
[2] L. Tsai,et al. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration , 1999, Nature.
[3] V. Nguyen,et al. IFN-γ Regulation of Class II Transactivator Promoter IV in Macrophages and Microglia: Involvement of the Suppressors of Cytokine Signaling-1 Protein , 2001, The Journal of Immunology.
[4] J. Trowsdale,et al. Genetic Control of MHC Class II Expression , 2002, Cell.
[5] Li-Huei Tsai,et al. Aberrant Cdk5 Activation by p25 Triggers Pathological Events Leading to Neurodegeneration and Neurofibrillary Tangles , 2003, Neuron.
[6] L. Tsai,et al. A Jekyll and Hyde kinase: roles for Cdk5 in brain development and disease , 2004, Current Opinion in Neurobiology.
[7] Petti T. Pang,et al. Opposing Roles of Transient and Prolonged Expression of p25 in Synaptic Plasticity and Hippocampus-Dependent Memory , 2005, Neuron.
[8] L. Tsai,et al. p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid β In Vivo , 2006, The Journal of Neuroscience.
[9] Geoffrey E. Hinton,et al. Visualizing Data using t-SNE , 2008 .
[10] P. L. Peng,et al. Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity , 2008, Neuron.
[11] Charles C. Kim,et al. Molecular definition of the identity and activation of natural killer cells , 2012, Nature Immunology.
[12] M. Daly,et al. Variant TREM2 as risk factor for Alzheimer's disease. , 2013, The New England journal of medicine.
[13] L. Tran,et al. Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease , 2013, Cell.
[14] A. Aguzzi,et al. Microglia: Scapegoat, Saboteur, or Something Else? , 2013, Science.
[15] Marco Prinz,et al. Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease , 2014, Nature Reviews Neuroscience.
[16] P. Kharchenko,et al. Bayesian approach to single-cell differential expression analysis , 2014, Nature Methods.
[17] I. Amit,et al. Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment , 2014, Cell.
[18] S. Gygi,et al. Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia , 2013, Nature Neuroscience.
[19] E. Hol,et al. Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction , 2014, Neurobiology of Aging.
[20] T. Wyss-Coray,et al. Microglial dysfunction in brain aging and Alzheimer's disease. , 2014, Biochemical pharmacology.
[21] Åsa K. Björklund,et al. Full-length RNA-seq from single cells using Smart-seq2 , 2014, Nature Protocols.
[22] Rona S. Gertner,et al. Single cell RNA Seq reveals dynamic paracrine control of cellular variation , 2014, Nature.
[23] T. Maniatis,et al. An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex , 2014, The Journal of Neuroscience.
[24] L. Probert. TNF and its receptors in the CNS: The essential, the desirable and the deleterious effects , 2015, Neuroscience.
[25] Manolis Kellis,et al. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease , 2015, Nature.
[26] D. Holtzman,et al. TREM2 lipid sensing sustains microglia response in an Alzheimer’s disease model , 2015, Cell.
[27] Rona S. Gertner,et al. Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity , 2015, Cell.
[28] A. Kröger,et al. DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity. , 2015, Immunity.
[29] Burkhard Becher,et al. Immune attack: the role of inflammation in Alzheimer disease , 2015, Nature Reviews Neuroscience.
[30] Mariella G. Filbin,et al. Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma , 2016, Nature.
[31] Emery N. Brown,et al. Author Correction: Gamma frequency entrainment attenuates amyloid load and modifies microglia , 2018, Nature.
[32] D. Bouvier,et al. High Resolution Dissection of Reactive Glial Nets in Alzheimer’s Disease , 2016, Scientific Reports.
[33] A. Nimmerjahn,et al. TAM receptors regulate multiple features of microglial physiology , 2016, Nature.
[34] I. Amit,et al. A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease , 2017, Cell.
[35] Manoj Kumar,et al. INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER’S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA , 2019, Alzheimer's & Dementia.
[36] M. Schaub,et al. SC3 - consensus clustering of single-cell RNA-Seq data , 2016, Nature Methods.
[37] R. Leite,et al. Transcriptomic analysis of purified human cortical microglia reveals age-associated changes , 2017, Nature Neuroscience.
[38] E. Blalock,et al. Transcriptional signatures of brain aging and Alzheimer’s disease: What are our rodent models telling us? , 2017, Behavioural Brain Research.