Direct assembling methodologies for high‐throughput bioscreening

Over the last few decades, high‐throughput (HT) bioscreening, a technique that allows rapid screening of biochemical compound libraries against biological targets, has been widely used in drug discovery, stem cell research, development of new biomaterials, and genomics research. To achieve these ambitions, scaffold‐free (or direct) assembly of biological entities of interest has become critical. Appropriate assembling methodologies are required to build an efficient HT bioscreening platform. The development of contact and non‐contact assembling systems as a practical solution has been driven by a variety of essential attributes of the bioscreening system, such as miniaturization, high throughput, and high precision. The present article reviews recent progress on these assembling technologies utilized for the construction of HT bioscreening platforms.

[1]  Hiroyuki Fujita,et al.  Positioning living cells on a high-density electrode array by negative dielectrophoresis , 2003 .

[2]  S. Bhatia,et al.  An extracellular matrix microarray for probing cellular differentiation , 2005, Nature Methods.

[3]  C. Owen,et al.  Magnetic labeling and cell sorting. , 1984, Journal of immunological methods.

[4]  N. K. Chaki,et al.  Self-assembled monolayers as a tunable platform for biosensor applications. , 2002, Biosensors & bioelectronics.

[5]  Andrew J deMello,et al.  Micro- and nanofluidic systems for high-throughput biological screening. , 2009, Drug discovery today.

[6]  Daniel G. Anderson,et al.  Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells , 2004, Nature Biotechnology.

[7]  Daniel Citterio,et al.  Inkjet-printed paperfluidic immuno-chemical sensing device , 2010, Analytical and bioanalytical chemistry.

[8]  Robert L Sah,et al.  Probing the role of multicellular organization in three-dimensional microenvironments , 2006, Nature Methods.

[9]  D. J. Harrison,et al.  Immunomagnetic T cell capture from blood for PCR analysis using microfluidic systems. , 2004, Lab on a chip.

[10]  Douglas B. Chrisey,et al.  Absorbing film assisted laser induced forward transfer of fungi (Trichoderma conidia) , 2004 .

[11]  Zsolt Bor,et al.  Survival and proliferative ability of various living cell types after laser-induced forward transfer. , 2005, Tissue engineering.

[12]  T. Boland,et al.  Inkjet printing of viable mammalian cells. , 2005, Biomaterials.

[13]  Tomokazu Matsue,et al.  Rapid micropatterning of living cells by repulsive dielectrophoretic force , 1997 .

[14]  Bradley R Ringeisen,et al.  Laser printing of pluripotent embryonal carcinoma cells. , 2004, Tissue engineering.

[15]  Mark M Davis,et al.  Molecular and functional analysis using live cell microarrays. , 2006, Current opinion in chemical biology.

[16]  Lorenz M Mayr,et al.  Novel trends in high-throughput screening. , 2009, Current opinion in pharmacology.

[17]  Rodriguez Devora,et al.  Fabrication Of Miniature Drug Screening Platform Using Low Cost Bioprinting Technology , 2010 .

[18]  Chad A. Mirkin,et al.  The use of nanoarrays for highly sensitive and selective detection of human immunodeficiency virus type 1 in plasma , 2004 .

[19]  Clement Kleinstreuer,et al.  Comparison of micro- and nano-size particle depositions in a human upper airway model , 2005 .

[20]  Robert W. Ashurst,et al.  Molecular Vapor Deposition - An Improved Vapor-Phase Deposition Technique of Molecular Coatings for MEMS Devices , 2004 .

[21]  B. Mosadegh,et al.  Nanoliter Liquid Patterning in Aqueous Environments for Spatially-defined Reagent Delivery to Mammalian Cells Hhs Public Access , 2022 .

[22]  H. Erfle,et al.  Transfected cell microarrays: an efficient tool for high-throughput functional analysis , 2007, Expert review of proteomics.

[23]  C. Mirkin,et al.  Applications of dip-pen nanolithography. , 2007, Nature nanotechnology.

[24]  Andreas Acrivos,et al.  Particle motions and segregation in dielectrophoretic microfluidics , 2003 .

[25]  H. Espinosa,et al.  Design and fabrication of a novel microfluidic nanoprobe , 2006, Journal of Microelectromechanical Systems.

[26]  H. A. Pohl.  The Motion and Precipitation of Suspensoids in Divergent Electric Fields , 1951 .

[27]  Colleen E Krause,et al.  Inkjet-printed gold nanoparticle electrochemical arrays on plastic. Application to immunodetection of a cancer biomarker protein. , 2011, Physical chemistry chemical physics : PCCP.

[28]  P. Benya,et al.  Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels , 1982, Cell.

[29]  J. M. Fernández-Pradas,et al.  Study of the laser-induced forward transfer of liquids for laser bioprinting , 2007 .

[30]  Robert L Sah,et al.  Geometric and material determinants of patterning efficiency by dielectrophoresis. , 2004, Biophysical journal.

[31]  Tao Xu,et al.  Viability and electrophysiology of neural cell structures generated by the inkjet printing method. , 2006, Biomaterials.

[32]  Terri Adams,et al.  Streamlining the Drug Discovery Process by Integrating Miniaturization, High Throughput Screening, High Content Screening, and Automation on the CellChip™ System , 1999 .

[33]  A. Ito,et al.  Magnetic force-based cell patterning using Arg-Gly-Asp (RGD) peptide-conjugated magnetite cationic liposomes. , 2007, Journal of bioscience and bioengineering.

[34]  A. Hierlemann,et al.  Patterned cell adhesion by self-assembled structures for use with a CMOS cell-based biosensor. , 2007, Biosensors & bioelectronics.

[35]  J A Barron,et al.  Biological Laser Printing: A Novel Technique for Creating Heterogeneous 3-dimensional Cell Patterns , 2004, Biomedical microdevices.

[36]  Nan Ma,et al.  Laser printing of skin cells and human stem cells. , 2010, Tissue engineering. Part C, Methods.

[37]  Mina J Bissell,et al.  Modeling tissue-specific signaling and organ function in three dimensions , 2003, Journal of Cell Science.

[38]  Joe Alper.  Biology and the Inkjets , 2004, Science.

[39]  Joe Alper.  Bioengineering. Biology and the inkjets. , 2004, Science.

[40]  David Bardenstein,et al.  Cell uptake and in vitro toxicity of magnetic nanoparticles suitable for drug delivery. , 2009, Molecular pharmaceutics.

[41]  Joel Voldman,et al.  Dielectrophoretic registration of living cells to a microelectrode array. , 2004, Biosensors & bioelectronics.

[42]  Martin L Yarmush,et al.  Living-cell microarrays. , 2009, Annual review of biomedical engineering.

[43]  M. Hayes,et al.  Flow-based microimmunoassay. , 2001, Analytical chemistry.

[44]  Hod Lipson,et al.  Direct Freeform Fabrication of Seeded Hydrogels in Arbitrary Geometries , 2022 .

[45]  Maria Dinescu,et al.  Excimer laser forward transfer of mammalian cells using a novel triazene absorbing layer , 2006 .

[46]  M. Heller,et al.  Electric manipulation of bioparticles and macromolecules on microfabricated electrodes. , 2001, Analytical chemistry.

[47]  Bradley R Ringeisen,et al.  Single-cell printing to form three-dimensional lines of olfactory ensheathing cells , 2008, Biomedical materials.

[48]  Shu Chien,et al.  Combinatorial signaling microenvironments for studying stem cell fate. , 2008, Stem cells and development.

[49]  Bruno Pignataro,et al.  Inkjet printing methodologies for drug screening. , 2010, Analytical chemistry.

[50]  M. Gijs,et al.  Manipulation of self-assembled structures of magnetic beads for microfluidic mixing and assaying. , 2004, Analytical chemistry.

[51]  Béatrice Schaack,et al.  2D and 3D cell microarrays in pharmacology. , 2009, Current opinion in pharmacology.

[52]  Wei Sun,et al.  Computer‐aided tissue engineering: overview, scope and challenges , 2004, Biotechnology and applied biochemistry.

[53]  J. Elisseeff,et al.  Photoencapsulation of chondrocytes in poly(ethylene oxide)-based semi-interpenetrating networks. , 2000, Journal of biomedical materials research.

[54]  S. Schreiber,et al.  Printing proteins as microarrays for high-throughput function determination. , 2000, Science.

[55]  J. Voldman,et al.  Holding forces of single-particle dielectrophoretic traps. , 2001, Biophysical journal.

[56]  F. Lin,et al.  Fabrication of viable tissue-engineered constructs with 3D cell-assembly technique. , 2005, Biomaterials.

[57]  S. Tatic-Lucic,et al.  Precise cell patterning using cytophobic self-assembled monolayer deposited on top of semi-transparent gold , 2010, Biomedical microdevices.

[58]  David J. Odde,et al.  Micro-Patterning of Animal Cells on PDMS Substrates in the Presence of Serum without Use of Adhesion Inhibitors , 2004, Biomedical microdevices.

[59]  Wei Zheng,et al.  A Cell-Based Ultra-High-Throughput Screening Assay for Identifying Inhibitors of D-Amino Acid Oxidase , 2006, Journal of biomolecular screening.

[60]  Mikkel Fougt Hansen,et al.  Characterization of a microfluidic magnetic bead separator for high-throughput applications , 2008 .

[61]  Chen Wang,et al.  Patterning of 293T fibroblasts on a mica surface , 2009, Analytical and bioanalytical chemistry.

[62]  A. Abbott.  Cell culture: Biology's new dimension , 2003, Nature.

[63]  G. Fuhr,et al.  Cultivation of cells under strong ac-electric field—differentiation between heating and trans-membrane potential effects , 1998 .

[64]  M. Ozkan,et al.  Electro-optical platform for the manipulation of live cells , 2003 .

[65]  Birgit Glasmacher,et al.  Laser printing of stem cells for biofabrication of scaffold-free autologous grafts. , 2011, Tissue engineering. Part C, Methods.

[66]  M. Gijs,et al.  Droplet-based DNA purification in a magnetic lab-on-a-chip. , 2006, Angewandte Chemie.

[67]  Umut A. Gurkan,et al.  Microengineering methods for cell-based microarrays and high-throughput drug-screening applications , 2011, Biofabrication.

[68]  T. Boland,et al.  Inkjet printing for high-throughput cell patterning. , 2004, Biomaterials.

[69]  Hiroyuki Honda,et al.  Cell patterning using magnetite nanoparticles and magnetic force , 2007, Biotechnology and bioengineering.

[70]  Chad A Mirkin,et al.  The power of the pen: development of massively parallel dip-pen nanolithography. , 2007, ACS nano.

[71]  Horacio Dante Espinosa,et al.  A multi-ink linear array of nanofountain probes , 2006 .

[72]  Horacio D Espinosa,et al.  A nanofountain probe with Sub-100 nm molecular writing resolution. , 2005, Small.

[73]  S. Britland,et al.  Cell reactions to dielectrophoretic manipulation. , 1999, Biochemical and biophysical research communications.

[74]  Xu,et al.  "Dip-Pen" nanolithography , 1999, Science.

[75]  Nicolas Kalogerakis,et al.  Dielectrophoretic forces can be safely used to retain viable cells in perfusion cultures of animal cells , 1999, Cytotechnology.

[76]  S. Tatic-Lucic,et al.  Cell patterning using molecular vapor deposition of self-assembled monolayers and lift-off technique. , 2011, Acta biomaterialia.

[77]  Kenneth M. Yamada,et al.  Cell interactions with three-dimensional matrices. , 2002, Current opinion in cell biology.

[78]  Eunkeu Oh,et al.  Magnetophoretic immunoassay of allergen-specific IgE in an enhanced magnetic field gradient. , 2007, Analytical chemistry.

[79]  A. Ito,et al.  Cell-patterning using poly (ethylene glycol)-modified magnetite nanoparticles. , 2009, Journal of biomedical materials research. Part A.

[80]  J. Park,et al.  Magnetic force-based multiplexed immunoassay using superparamagnetic nanoparticles in microfluidic channel. , 2005, Lab on a chip.

[81]  Harry Heinzelmann,et al.  Nanodispenser for attoliter volume deposition using atomic force microscopy probes modified by focused-ion-beam milling , 2004 .

[82]  Y. Ito,et al.  Surface micropatterning to regulate cell functions. , 1999, Biomaterials.

[83]  Barry J. Spargo,et al.  Biological laser printing of three dimensional cellular structures , 2004 .

[84]  Yong Huang,et al.  Laser-based direct-write techniques for cell printing , 2010, Biofabrication.

[85]  P. Morais,et al.  Biological effects of magnetic fluids: toxicity studies , 1999 .