Acute toxicity screening of novel AChE inhibitors using neuronal networks on microelectrode arrays.

[1]  G. Gross,et al.  Drug evaluations using neuronal networks cultured on microelectrode arrays. , 2000, Biosensors & bioelectronics.

[2]  H. Parnas,et al.  Block of quantal end-plate currents of mouse muscle by physostigmine and procaine. , 1999, Journal of neurophysiology.

[3]  M. Oortgiesen,et al.  Differential effects of physostigmine and organophosphates on nicotinic receptors in neuronal cells of different species. , 1998, Neurotoxicology.

[4]  J. Kauer,et al.  Properties of carbachol-induced oscillatory activity in rat hippocampus. , 1997, Journal of neurophysiology.

[5]  R. Elde,et al.  Vesicular acetylcholine transporter (VAChT) protein: A novel and unique marker for cholinergic neurons in the central and peripheral nervous systems , 1997, The Journal of comparative neurology.

[6]  A. Levey,et al.  Muscarinic acetylcholine receptor subtype, m2: diverse functional implications of differential synaptic localization. , 1997, Life sciences.

[7]  A. Harsch,et al.  Odor, drug and toxin analysis with neuronal networks in vitro: extracellular array recording of network responses. , 1997, Biosensors & bioelectronics.

[8]  M. Raiteri,et al.  Nicotinic Autoreceptors Mediating Enhancement of Acetylcholine Release Become Operative in Conditions of “Impaired” Cholinergic Presynaptic Function , 1996, Journal of neurochemistry.

[9]  S. Brimijoin,et al.  Highly Potent, Selective, and Low Cost Bis-tetrahydroaminacrine Inhibitors of Acetylcholinesterase , 1996, The Journal of Biological Chemistry.

[10]  L. Role,et al.  Presynaptic ionotropic receptors , 1996, Current Opinion in Neurobiology.

[11]  G. Gross,et al.  The use of neuronal networks on multielectrode arrays as biosensors. , 1995, Biosensors & bioelectronics.

[12]  Thomas M. McKenna,et al.  Enabling Technologies for Cultured Neural Networks , 1994 .

[13]  G. Gross,et al.  A closed flow chamber for long-term multichannel recording and optical monitoring , 1994, Journal of Neuroscience Methods.

[14]  L. Descarries,et al.  Recovery of choline acetyltransferase activity without sprouting of the residual acetylcholine innervation in adult rat cerebral cortex after lesion of the nucleus basalis , 1993, Brain Research.

[15]  P. Goering Lead-protein interactions as a basis for lead toxicity. , 1993, Neurotoxicology.

[16]  C. Trouth,et al.  Cholinergic-opioid interactions at brainstem respiratory chemosensitive areas in cats. , 1993, Neurotoxicology.

[17]  E. Vizi,et al.  Heterogeneity of presynaptic muscarinic receptors involved in modulation of transmitter release , 1989, Neuroscience.

[18]  G. Gross,et al.  Transparent indium-tin oxide electrode patterns for extracellular, multisite recording in neuronal cultures , 1985, Journal of Neuroscience Methods.

[19]  G. Gross Simultaneous Single Unit Recording in vitro with a Photoetched Laser Deinsulated Gold Multimicroelectrode Surface , 1979, IEEE Transactions on Biomedical Engineering.

[20]  R. M. Krupka,et al.  Molecular Mechanisms for Hydrolytic Enzyme Action. I. Apparent Non-competitive Inhibition, with Special Reference to Acetylcholinesterase , 1961 .