Fraction of unsaturated fatty acids in visceral adipose tissue (VAT) is lower in subjects with high total VAT volume – a combined 1H MRS and volumetric MRI study in male subjects

Visceral adipose tissue (VAT) is thought to play an important role in the pathogenesis of obesity and insulin resistance. However, little is known about the composition of VAT with regard to the amount of mono‐ (MUFAs) and polyunsaturated fatty acids (PUFAs) in triglycerides. Volume‐selective MRS was performed in addition to MRI for the quantification of VAT. Analysis comprised proton signals from the vinyl‐H group (H–C = C–H), including protons from MUFA + PUFA, and diallylic‐H, i.e. methylene‐interrupted PUFAs. The methyl (−CH3) resonance, which is the only peak with a defined number of protons/triglyceride (n = 9), served as reference.

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