Fiber photo-catheters for laser treatment of atrial fibrillation.

A fiber photo-catheter has been developed for surgical treatment of atrial fibrillation with laser radiation. Atrial fibrillation (AF) is a heart rhythm abnormality that involves irregular and rapid heartbeats. Recent studies demonstrate the superiority of treating AF disease with optical radiation of the near infrared region. To produce long continuous transmural lesions, solid-state lasers and laser diodes, along with end-emitting fiber catheters, have been used experimentally. The absence of side-emitting flexible catheters with the ability to produce long continuous lesions limits the further development of this technology. In this research, a prototype of an optical catheter, consisting of a flexible 10-cm fiber diffuser has been used to make continuous photocoagulation lesions for effective maze procedure treatments. The system also includes: a flexible optical reflector; a series of openings for rapid self-attachment to the tissue; and an optional closed-loop irrigating chamber with circulating saline to cool the optical diffuser and irrigate the tissue.

[1]  Kyriacos Kalli,et al.  Fiber Bragg Gratings: Fundamentals and Applications in Telecommunications and Sensing , 2000 .

[2]  Martin G. Mack,et al.  Interstitial photodynamic laser therapy in interventional oncology , 2004, European Radiology.

[3]  H. Halperin,et al.  Linear lesions in myocardium created by Nd:YAG laser using diffusing optical fibers: In vitro and in vivo results , 2000, Lasers in surgery and medicine.

[4]  Harry T. Whelan,et al.  Evaluation of Photodynamic Therapy near Functional Brain Tissue in Patients with Recurrent Brain Tumors , 2004, Journal of Neuro-Oncology.

[5]  J. Boineau,et al.  The development of the Maze procedure for the treatment of atrial fibrillation. , 2000, Seminars in thoracic and cardiovascular surgery.

[6]  Dexiu Huang,et al.  Highly sensitive chemical sensor based on the measurement of the separation of dual resonant peaks in a 100-μm-period fiber grating , 1999 .

[7]  A. Vengsarkar,et al.  Optical fiber long-period grating sensors. , 1996, Optics letters.

[8]  J Feinberg,et al.  Long-period fiber gratings with variable coupling for real-time sensing applications. , 2000, Optics letters.

[9]  L. Lilge,et al.  Thin cylindrical diffusers in multimode Ge‐doped silica fibers , 2005, Lasers in surgery and medicine.

[10]  K. Hill,et al.  Narrow-band Bragg reflectors in optical fibers. , 1978, Optics letters.

[11]  Lothar Lilge,et al.  Design and performance of thin cylindrical diffusers created in Ge-doped multimode optical fibers. , 2005, Applied optics.

[12]  P B Corr,et al.  The surgical treatment of atrial fibrillation. III. Development of a definitive surgical procedure. , 1991, The Journal of thoracic and cardiovascular surgery.

[13]  John E. Sipe,et al.  Long-period fiber gratings as band-rejection filters , 1995 .

[14]  Julian D. C. Jones,et al.  Handbook of Laser Technology and Applications , 2004 .

[15]  Vladimir Rubtsov,et al.  Long-period gratings in optical fibres for chemical sensor applications , 2005 .

[16]  Lothar Lilge,et al.  Performance evaluation of cylindrical fiber optic light diffusers for biomedical applications , 2004, Lasers in surgery and medicine.