Improved Fuzzy Connectedness Segmentation Method for Medical Images with Multiple Seeds in MRI

Image segmentation is a key step in medical image processing, since it affects the quality of the medical image in the follow-up steps. However, in the practice of processing MRI images, we find out that the segmentation process involves much difficulty due to the poorly defined boundaries of medical images, meanwhile, there are usually more than one target area. In this study, an improved algorithm based on the fuzzy connectedness framework for medical image is developed. The improved algorithm has involved an adaptive fuzzy connectedness segmentation combined with multiple seeds selection. Also, the algorithm can effectively overcome many problems when manual selection is used, such as the un-precise result of each target region segmented of the medical image and the difficulty of completion the segmentation when the areas are not connected. For testing the proposed method, some original real images, taken from a large hospital, were analyzed. The results have been evaluated with some rules, such as Dice’s coefficient, over segmentation rate, and under segmentation rate. The results show that the proposed method has an ideal segmentation boundary on medical images, meanwhile, it has a low time cost. In conclusion, the proposed method is superior to the traditional fuzzy connectedness segmentation methods for medical images.

[1]  Jayaram K. Udupa,et al.  Fuzzy connectedness and image segmentation , 2003, Proc. IEEE.

[2]  Supun Samarasekera,et al.  Fuzzy Connectedness and Object Definition: Theory, Algorithms, and Applications in Image Segmentation , 1996, CVGIP Graph. Model. Image Process..

[3]  Jayaram K. Udupa,et al.  Fuzzy-connected 3D image segmentation at interactive speeds , 2000, Graph. Model..

[4]  Qian Wang,et al.  Thalamic segmentation based on improved fuzzy connectedness in structural MRI , 2015, Comput. Biol. Medicine.

[5]  Jian-Jiang Pan An Image Segmentation and Its Algorithm Based on Fuzzy Connectedness , 2005 .

[6]  Yunping Zheng,et al.  A fast region segmentation algorithm on compressed gray images using Non-symmetry and Anti-packing Model and Extended Shading representation , 2016, J. Vis. Commun. Image Represent..

[7]  Jayaram K. Udupa,et al.  A hybrid method for airway segmentation and automated measurement of bronchial wall thickness on CT , 2015, Medical Image Anal..

[8]  Jayaram K. Udupa,et al.  Fuzzy Connectedness Image Segmentation in Graph Cut Formulation: A Linear-Time Algorithm and a Comparative Analysis , 2012, Journal of Mathematical Imaging and Vision.

[9]  Jayaram K. Udupa,et al.  Joint graph cut and relative fuzzy connectedness image segmentation algorithm , 2013, Medical Image Anal..

[10]  Sung-Bae Cho,et al.  Edge Preserving Region Growing for Aerial Color Image Segmentation , 2015, ICIC 2015.

[11]  Yuhui Zheng,et al.  Image segmentation by generalized hierarchical fuzzy C-means algorithm , 2015, J. Intell. Fuzzy Syst..

[12]  Said Ghnomiey Medical Image Segmentation Techniques: An Overview , 2016 .

[13]  Chen Yuquan Visual attention guidance and region competition for medical image segmentation , 2007 .

[14]  Sun Yu-la Research on the Application and Development of Digital Image Processing Technology , 2014 .

[15]  Rasoul Khayati,et al.  Fully automated tumor segmentation based on improved fuzzy connectedness algorithm in brain MR images , 2011, Comput. Biol. Medicine.

[16]  J. Alison Noble,et al.  Feature-based fuzzy connectedness segmentation of ultrasound images with an object completion step , 2015, Medical Image Anal..

[17]  Ahmad Ayatollahi,et al.  An efficient neural network based method for medical image segmentation , 2014, Comput. Biol. Medicine.

[18]  Jing Bai,et al.  Atlas-Based Fuzzy Connectedness Segmentation and Intensity Nonuniformity Correction Applied to Brain MRI , 2007, IEEE Transactions on Biomedical Engineering.

[19]  Paulo André Vechiatto Miranda,et al.  Oriented relative fuzzy connectedness: theory, algorithms, and its applications in hybrid image segmentation methods , 2015, EURASIP J. Image Video Process..

[20]  Jayaram K. Udupa,et al.  Iterative relative fuzzy connectedness for multiple objects with multiple seeds , 2007, Comput. Vis. Image Underst..

[21]  S. A. Ladhake,et al.  A Review on Brain Tumor Detection Using Segmentation And Threshold Operations , 2014 .

[22]  Vasileios Megalooikonomou,et al.  Integrating edge detection and fuzzy connectedness for automated segmentation of anatomical branching structures , 2014, Int. J. Bioinform. Res. Appl..