From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
暂无分享,去创建一个
F. Bäckhed | A. Koh | P. Kovatcheva-Datchary | Fredrik Bäckhed | Petia Kovatcheva-Datchary | Ara Koh | Filipe De Vadder | F. Vadder
[1] T. Junt,et al. Triggering the succinate receptor GPR91 on dendritic cells enhances immunity , 2008, Nature Immunology.
[2] E. N. Bergman. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. , 1990, Physiological reviews.
[3] D. Connolly,et al. (d)-β-Hydroxybutyrate Inhibits Adipocyte Lipolysis via the Nicotinic Acid Receptor PUMA-G* , 2005, Journal of Biological Chemistry.
[4] J. Clemente,et al. Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice , 2013, Science.
[5] D. Chuang,et al. The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain , 2009, Journal of neurochemistry.
[6] K. Murthy,et al. The short chain fatty acids, butyrate and propionate, have differential effects on the motility of the guinea pig colon , 2014, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[7] Jimmy D Bell,et al. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism , 2014, Nature Communications.
[8] Masashi Yanagisawa,et al. Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41 , 2008, Proceedings of the National Academy of Sciences.
[9] B. Golding,et al. Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein. , 2003, European journal of biochemistry.
[10] Wei Sun,et al. The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation. , 2012, Molecular cell.
[11] P. Deen,et al. The Succinate Receptor as a Novel Therapeutic Target for Oxidative and Metabolic Stress-Related Conditions , 2012, Front. Endocrin..
[12] S. Kash,et al. Role of GPR81 in lactate-mediated reduction of adipose lipolysis. , 2008, Biochemical and biophysical research communications.
[13] G. Cresci,et al. GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. , 2009, Cancer research.
[14] Hua V. Lin,et al. Butyrate and Propionate Protect against Diet-Induced Obesity and Regulate Gut Hormones via Free Fatty Acid Receptor 3-Independent Mechanisms , 2012, PloS one.
[15] F. Bäckhed,et al. Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella. , 2015, Cell metabolism.
[16] H. Flint,et al. Acetate Utilization and Butyryl Coenzyme A (CoA):Acetate-CoA Transferase in Butyrate-Producing Bacteria from the Human Large Intestine , 2002, Applied and Environmental Microbiology.
[17] M. Bohlooly-y,et al. Improved glucose control and reduced body fat mass in free fatty acid receptor 2-deficient mice fed a high-fat diet. , 2011, American journal of physiology. Endocrinology and metabolism.
[18] J. Tiedje,et al. Revealing the Bacterial Butyrate Synthesis Pathways by Analyzing (Meta)genomic Data , 2014, mBio.
[19] R. Flavell,et al. Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome , 2015, Nature Communications.
[20] R. P. Ross,et al. Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues. , 2009, The American journal of clinical nutrition.
[21] W. D. de Vos,et al. Insight into the prebiotic concept: lessons from an exploratory, double blind intervention study with inulin-type fructans in obese women , 2012, Gut.
[22] M. Parmentier,et al. Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation* , 2003, Journal of Biological Chemistry.
[23] D. Green,et al. HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells , 2011, The Journal of experimental medicine.
[24] W. Garrett,et al. The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis , 2013, Science.
[25] K. Bracke,et al. Eosinophils in the Spotlight: Eosinophilic airway inflammation in nonallergic asthma , 2013, Nature Medicine.
[26] S. Dowell,et al. The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids* , 2003, The Journal of Biological Chemistry.
[27] G. Macfarlane,et al. Dissimilatory amino Acid metabolism in human colonic bacteria. , 1997, Anaerobe.
[28] S. Holgate,et al. The sentinel role of the airway epithelium in asthma pathogenesis , 2011, Immunological reviews.
[29] Olivia I. Koues,et al. The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites , 2016, Cell.
[30] Huidong Shi,et al. Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. , 2014, Immunity.
[31] P. de Coppet,et al. Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats. , 2010, Gastroenterology.
[32] T. Schwartz,et al. Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia , 2015, Neuroscience.
[33] H. Flint,et al. High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health. , 2011, The American journal of clinical nutrition.
[34] Jinhai Gao,et al. Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors , 2004, Nature.
[35] Liping Zhao,et al. Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers , 2011, The ISME Journal.
[36] Lai Guan Ng,et al. The gut microbiota influences blood-brain barrier permeability in mice , 2014, Science Translational Medicine.
[37] HIF1a–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells , 2011 .
[38] B. Wilson,et al. Gut Microbial Metabolism Drives Transformation of Msh2-Deficient Colon Epithelial Cells , 2014, Cell.
[39] R. Inoue,et al. Non‐neuronal release of ACh plays a key role in secretory response to luminal propionate in rat colon , 2011, The Journal of physiology.
[40] I. Amit,et al. Host microbiota constantly control maturation and function of microglia in the CNS , 2015, Nature Neuroscience.
[41] Robert J. Moore,et al. Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites , 2015, Nature Communications.
[42] G. Macfarlane,et al. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. , 1987, Gut.
[43] G. Tsujimoto,et al. The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43 , 2013, Nature Communications.
[44] F. Kamme,et al. Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81* , 2009, Journal of Biological Chemistry.
[45] Jacques Ferlay,et al. The global burden of cancers attributable to infections in the year 2008: a review and synthetic analysis Web appendix section , 2012 .
[46] G. Macfarlane,et al. Bacteria, colonic fermentation, and gastrointestinal health. , 2012, Journal of AOAC International.
[47] W. Cefalu,et al. Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice , 2009, Diabetes.
[48] K. Whaley,et al. Origins of vaginal acidity: high D/L lactate ratio is consistent with bacteria being the primary source. , 2001, Human reproduction.
[49] Amanda G. Henry,et al. Gut microbiome of the Hadza hunter-gatherers , 2014, Nature Communications.
[50] N. Lambert,et al. Blockade of Dendritic Cell Development by Bacterial Fermentation Products Butyrate and Propionate through a Transporter (Slc5a8)-dependent Inhibition of Histone Deacetylases , 2010, The Journal of Biological Chemistry.
[51] B. Hudson,et al. Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3* , 2012, The Journal of Biological Chemistry.
[52] N. Pace,et al. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases , 2007, Proceedings of the National Academy of Sciences.
[53] A. Rudensky,et al. Metabolites produced by commensal bacteria promote peripheral regulatory T cell generation , 2013, Nature.
[54] J. Faith,et al. Dissecting the in Vivo Metabolic Potential of Two Human Gut Acetogens , 2010, The Journal of Biological Chemistry.
[55] F. Bäckhed,et al. Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits , 2014, Cell.
[56] A. M. Habib,et al. Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2 , 2012, Diabetes.
[57] F. Guarner,et al. Role of intestinal microflora in chronic inflammation and ulceration of the rat colon. , 1994, Gut.
[58] Takafumi Hara,et al. Short-chain fatty acids and ketones directly regulate sympathetic nervous system via G protein-coupled receptor 41 (GPR41) , 2011, Proceedings of the National Academy of Sciences.
[59] S. Tunaru,et al. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect , 2003, Nature Medicine.
[60] Svati H Shah,et al. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. , 2009, Cell metabolism.
[61] J. Lupton. Microbial degradation products influence colon cancer risk: the butyrate controversy. , 2004, The Journal of nutrition.
[62] Sang-Uk Seo,et al. Role of the gut microbiota in immunity and inflammatory disease , 2013, Nature Reviews Immunology.
[63] Takafumi Hara,et al. Short-chain fatty acids and ketones directly regulate sympathetic nervous system via GPR 41 , 2016 .
[64] T. Schwartz,et al. GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes. , 2013, Endocrinology.
[65] B. Olde,et al. Identification of a free fatty acid receptor, FFA2R, expressed on leukocytes and activated by short-chain fatty acids. , 2003, Biochemical and biophysical research communications.
[66] A. Schwiertz,et al. Microbiota and SCFA in Lean and Overweight Healthy Subjects , 2010, Obesity.
[67] S. Dowell,et al. Molecular Identification of High and Low Affinity Receptors for Nicotinic Acid* , 2003, The Journal of Biological Chemistry.
[68] R. Medzhitov. Origin and physiological roles of inflammation , 2008, Nature.
[69] C. Mayer,et al. Whole-Genome Transcription Profiling Reveals Genes Up-Regulated by Growth on Fucose in the Human Gut Bacterium “Roseburia inulinivorans” , 2006, Journal of bacteriology.
[70] Jimmy D Bell,et al. Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults , 2014, Gut.
[71] G. Cresci,et al. Colonic Gene Expression in Conventional and Germ-Free Mice with a Focus on the Butyrate Receptor GPR109A and the Butyrate Transporter SLC5A8 , 2010, Journal of Gastrointestinal Surgery.
[72] D. Yoo,et al. Synergistic Effects of Sodium Butyrate, a Histone Deacetylase Inhibitor, on Increase of Neurogenesis Induced by Pyridoxine and Increase of Neural Proliferation in the Mouse Dentate Gyrus , 2011, Neurochemical Research.
[73] M. Tomita,et al. Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells , 2013, Nature.
[74] Mikhail Tikhonov,et al. Diet-induced extinction in the gut microbiota compounds over generations , 2015, Nature.
[75] T. Wiele,et al. Arabinoxylan‐oligosaccharides (AXOS) affect the protein/carbohydrate fermentation balance and microbial population dynamics of the Simulator of Human Intestinal Microbial Ecosystem , 2008, Microbial biotechnology.
[76] Tomoko Kayashima,et al. Cecal succinate elevated by some dietary polyphenols may inhibit colon cancer cell proliferation and angiogenesis. , 2014, Journal of agricultural and food chemistry.
[77] Yi Zhang,et al. Butyrate Promotes Induced Pluripotent Stem Cell Generation* , 2010, The Journal of Biological Chemistry.
[78] M. Rumbo,et al. Is lactate an undervalued functional component of fermented food products? , 2015, Front. Microbiol..
[79] D. Nie,et al. G‐protein‐coupled receptor for short‐chain fatty acids suppresses colon cancer , 2011, International journal of cancer.
[80] G. Macfarlane,et al. The control and consequences of bacterial fermentation in the human colon. , 1991, The Journal of applied bacteriology.
[81] Ricky W. Johnstone,et al. Histone-deacetylase inhibitors: novel drugs for the treatment of cancer , 2002, Nature Reviews Drug Discovery.
[82] E. van Santen,et al. Short-chain fatty acids and succinate in feces of healthy human volunteers and their correlation with anaerobe cultural counts. , 1987, Scandinavian journal of gastroenterology.
[83] H. Flint,et al. Role of the gut microbiota in nutrition and health , 2018, British Medical Journal.
[84] J. Cummings,et al. Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers. , 1990, The American journal of gastroenterology.
[85] J. Karp,et al. Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny , 2013, Nature Methods.
[86] R. Medzhitov,et al. The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition , 2014, Proceedings of the National Academy of Sciences.
[87] S. Kang,et al. Short chain fatty acids induce both effector and regulatory T cells by suppression of histone deacetylases and regulation of the mTOR-S6K pathway , 2014, Mucosal Immunology.
[88] J. Rougemont,et al. The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation , 2015, Immunity.
[89] S. Mazmanian,et al. A microbial symbiosis factor prevents intestinal inflammatory disease , 2008, Nature.
[90] C. Knauf,et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia , 2007, Diabetologia.
[91] E. Mardis,et al. An obesity-associated gut microbiome with increased capacity for energy harvest , 2006, Nature.
[92] H. Vidal,et al. Insulin-sensitizing effects of dietary resistant starch and effects on skeletal muscle and adipose tissue metabolism. , 2005, The American journal of clinical nutrition.
[93] Harry J. Flint,et al. The gut microbiota, bacterial metabolites and colorectal cancer , 2014, Nature Reviews Microbiology.
[94] Petia Kovatcheva-Datchary,et al. The Gut Microbiota , 2013 .
[95] H. Yamashita,et al. Improvement of Obesity and Glucose Tolerance by Acetate in Type 2 Diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) Rats , 2007, Bioscience, biotechnology, and biochemistry.
[96] R. Xavier,et al. Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43 , 2009, Nature.
[97] T. Junt,et al. Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis , 2014, Nature Medicine.
[98] G. Mithieux,et al. Vasoactive intestinal peptide is a local mediator in a gut‐brain neural axis activating intestinal gluconeogenesis , 2015, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
[99] T. Wolever,et al. Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-α , 2009, British Journal of Nutrition.
[100] G. Reid,et al. Oral use of Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 significantly alters vaginal flora: randomized, placebo-controlled trial in 64 healthy women. , 2003, FEMS immunology and medical microbiology.
[101] H. Flint,et al. Restricted Distribution of the Butyrate Kinase Pathway among Butyrate-Producing Bacteria from the Human Colon , 2004, Journal of bacteriology.
[102] M. Hartmann,et al. Early life antibiotic‐driven changes in microbiota enhance susceptibility to allergic asthma , 2012, EMBO reports.
[103] S. Ragsdale,et al. Acetogenesis and the Wood-Ljungdahl pathway of CO(2) fixation. , 2008, Biochimica et biophysica acta.