Mechanisms of aneuploidy.

[1]  F. Mitelman,et al.  Chromosomes and cancer , 2009 .

[2]  K. Kinzler,et al.  Genetic instability in colorectal cancers , 1997, Nature.

[3]  Bert Vogelstein,et al.  Mutations of mitotic checkpoint genes in human cancers , 1998, Nature.

[4]  D. Cimini,et al.  Differences in malsegregation rates obtained by scoring ana-telophases or binucleate cells. , 1999, Mutagenesis.

[5]  Alexey Khodjakov,et al.  Merotelic Kinetochore Orientation Is a Major Mechanism of Aneuploidy in Mitotic Mammalian Tissue Cells , 2001, The Journal of cell biology.

[6]  S. Rehen,et al.  Chromosomal variation in neurons of the developing and adult mammalian nervous system , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[7]  P. Hunt,et al.  To err (meiotically) is human: the genesis of human aneuploidy , 2001, Nature Reviews Genetics.

[8]  Erich A. Nigg,et al.  Centrosome aberrations: cause or consequence of cancer progression? , 2002, Nature Reviews Cancer.

[9]  D. Cimini,et al.  Merotelic kinetochore orientation occurs frequently during early mitosis in mammalian tissue cells and error correction is achieved by two different mechanisms , 2003, Journal of Cell Science.

[10]  David Pellman,et al.  Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells , 2005, Nature.

[11]  J. Chun,et al.  Aneuploid neurons are functionally active and integrated into brain circuitry , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[12]  S. Gollin,et al.  Spindle Multipolarity Is Prevented by Centrosomal Clustering , 2005, Science.

[13]  D. Hansemann Ueber asymmetrische Zelltheilung in Epithelkrebsen und deren biologische Bedeutung , 1890, Archiv für pathologische Anatomie und Physiologie und für klinische Medicin.

[14]  E. Revenkova,et al.  SMC1β-deficient female mice provide evidence that cohesins are a missing link in age-related nondisjunction , 2005, Nature Genetics.

[15]  Y. Yung,et al.  Constitutional Aneuploidy in the Normal Human Brain , 2005, The Journal of Neuroscience.

[16]  B. Weaver,et al.  Does aneuploidy cause cancer? , 2006, Current opinion in cell biology.

[17]  Neil J Ganem,et al.  Tetraploidy, aneuploidy and cancer. , 2007, Current opinion in genetics & development.

[18]  Y. Lazebnik,et al.  A Virus Causes Cancer by Inducing Massive Chromosomal Instability through Cell Fusion , 2007, Current Biology.

[19]  Maitreya J. Dunham,et al.  Effects of Aneuploidy on Cellular Physiology and Cell Division in Haploid Yeast , 2007, Science.

[20]  Y. Lazebnik,et al.  Cell-to-cell fusion as a link between viruses and cancer , 2007, Nature Reviews Cancer.

[21]  S. Bickel,et al.  Aging Predisposes Oocytes to Meiotic Nondisjunction When the Cohesin Subunit SMC1 Is Reduced , 2008, PLoS genetics.

[22]  Angelika Amon,et al.  Aneuploidy: Cells Losing Their Balance , 2008, Genetics.

[23]  G. Parmigiani,et al.  Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers , 2008, Proceedings of the National Academy of Sciences.

[24]  Angelika Amon,et al.  Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells , 2008, Science.

[25]  Duane A. Compton,et al.  Examining the link between chromosomal instability and aneuploidy in human cells , 2008, The Journal of cell biology.

[26]  D. Compton,et al.  Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability , 2009, Current Biology.

[27]  Samuel F. Bakhoum,et al.  Genome stability is ensured by temporal control of kinetochore-microtubule dynamics , 2008, Nature Cell Biology.

[28]  David Pellman,et al.  A Mechanism Linking Extra Centrosomes to Chromosomal Instability , 2009, Nature.

[29]  M. Lampson,et al.  Evidence that Weakened Centromere Cohesion Is a Leading Cause of Age-Related Aneuploidy in Oocytes , 2010, Current Biology.

[30]  N. Dyson,et al.  Loss of pRB causes centromere dysfunction and chromosomal instability. , 2010, Genes & development.

[31]  D. Compton,et al.  Mechanisms of Chromosomal Instability , 2010, Current Biology.

[32]  F. Dick,et al.  Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive. , 2010, Genes & development.

[33]  Duane A. Compton,et al.  Proliferation of aneuploid human cells is limited by a p53-dependent mechanism , 2010, The Journal of cell biology.

[34]  Chromosome Instability Is Common in Human Cleavage-Stage Embryos , 2012 .