Rapid, one-pot synthesis of α,α-disubstituted primary amines by the addition of Grignard reagents to nitriles under microwave heating conditions

[1]  J. Quinn,et al.  1,4-Cyclohexadiene with Pd/C as a rapid, safe transfer hydrogenation system with microwave heating , 2008 .

[2]  J. Quinn,et al.  Expedient Lewis acid catalyzed synthesis of a 3-substituted 5-arylidene-1-methyl-2-thiohydantoin Library. , 2007, Journal of combinatorial chemistry.

[3]  B. T. Gregg,et al.  Pyrazolo[1,5-a]pyrimidines. Identification of the privileged structure and combinatorial synthesis of 3-(hetero)arylpyrazolo[1,5-a]pyrimidine-6-carboxamides. , 2007, Journal of combinatorial chemistry.

[4]  C. Lindsley,et al.  Synthesis and SAR of GlyT1 inhibitors derived from a series of N-((4-(morpholine-4-carbonyl)-1-(propylsulfonyl)piperidin-4-yl)methyl)benzamides. , 2006, Bioorganic & medicinal chemistry letters.

[5]  C. Bender,et al.  Room temperature hydroamination of N-alkenyl ureas catalyzed by a gold(i) N-heterocyclic carbene complex. , 2006, Organic letters.

[6]  D. Rognan,et al.  N1-Benzoyl-N2-[1-(1-naphthyl)ethyl]-trans-1,2-diaminocyclohexanes: Development of 4-chlorophenylcarboxamide (calhex 231) as a new calcium sensing receptor ligand demonstrating potent calcilytic activity. , 2006, Journal of medicinal chemistry.

[7]  J. Marrot,et al.  3-Aminopyrrolidines via ring rearrangement of 2-aminomethylazetidines. Synthesis of (-)-absouline. , 2005, Organic letters.

[8]  Hong-jun Wang,et al.  Microwave-assisted synthesis of 1-aryl-1H-indazoles via one-pot two-step Cu-catalyzed intramolecular N-arylation of arylhydrazones , 2005 .

[9]  Hong-jun Wang,et al.  Microwave-assisted cross-coupling of 3-chloro-2-pyrazolines and 3-chloro-1-phenyl-1,4,5,6-tetrahydropyridazine with aryl boronic acids , 2005 .

[10]  D. Sauer,et al.  Rapid and efficient synthesis of 1,2,4-oxadiazoles utilizing polymer-supported reagents under microwave heating. , 2005, Organic letters.

[11]  Ying Han,et al.  Efficient synthesis of 4-aminoquinazoline and thieno[3,2-d]pyrimidin-4-ylamine derivatives by microwave irradiation. , 2004, Organic letters.

[12]  D. Sauer,et al.  Use of polymer-supported Pd reagents for rapid and efficient Suzuki reactions using microwave heating. , 2004, Organic letters.

[13]  D. Sauer,et al.  Microwave-assisted synthesis utilizing supported reagents: a rapid and efficient acylation procedure. , 2003, Organic letters.

[14]  Sven Mangelinckx,et al.  Synthesis of substituted benzhydrylamines , 2002 .

[15]  S. Hall,et al.  Copper(I)-activated addition of Grignard reagents to nitriles. Synthesis of ketimines, ketones, and amines , 1987 .

[16]  S. Hall,et al.  Tandem alkylation-reduction of nitriles. Synthesis of branched primary amines , 1986 .

[17]  B. T. Gregg,et al.  Solution Phase Synthesis of a 3,5,7-Substituted Indolin-2-one Library as Potential CDK2 Inhibitor Isosteres , 2008 .

[18]  M. Larhed,et al.  Microwave methods in organic synthesis , 2006 .

[19]  E. Paietta,et al.  [Pharmacological Properties of Fendiline in Cardiac and Smooth Muscle (author's transl)]. , 1976, Arzneimittel-Forschung.

[20]  W. Oelssner,et al.  [On the effect of aminoacetonitrile and alpha-phenyl-alpha-(1-phenylisopropyl)-amino-acetonitrile on the skeletal system of the skeletal system of the white rat in subchronic overfeeding]. , 1968, Acta biologica et medica Germanica.