Arteriohepatic dysplasia.

oleic acid increased the unconjugated bilirubin in the liver slices. I cannot agree that it is only breast milks from mothers of children with breast milk jaundice which develop increased inhibition to bilirubin conjugation on storage. The original observation (Hargreaves, 1970) that this could occur in milk from mothers of nonjaundiced children has been confirmed (Bevan and Holton, 1972). These authors also showed that the increased activity was associated with an increase in the free fatty acid content of the milk. The observation was thought to have practical implications in that deep-frozen milk is used for feeding premature infants, but it was shown that the inhibitory activity does not develop in sterilized milk (Hargreaves, 1970). TOM HARGREAVES Area Department of Pathology, Church Lane, Heavitree, Exeter, Devon EX2 5AD.