Design of an expert system and its application to dermatopathology

Expert systems are computer programs which use inference and knowledge to solve problems which usually require the expertise of a human specialist. This paper examines the application of expert systems to histopathology and explains their construction by describing the design of an expert system ‘dermdx’, intended to aid in the interpretation and diagnosis of biopsies of inflammatory diseases of the skin. The system consists of an expert shell, which performs the inference, and a rule‐base, which contains the knowledge with which the system operates. The system can be easily updated or adapted to other tasks.