Assessment of hyperpolarized 3He lung MRI for regional evaluation of interventional therapy: A pilot study in pediatric cystic fibrosis

To determine whether regional changes in lung ventilation in a group of pediatric cystic fibrosis (CF) patients following a course of chest physiotherapy could be detected with 3He MRI.

[1]  J. Gustafson,et al.  Cystic Fibrosis , 2009, Journal of the Iowa Medical Society.

[2]  W. Hop,et al.  Lung morphology assessment using MRI: A robust ultra‐short TR/TE 2D steady state free precession sequence used in cystic fibrosis patients , 2009, Magnetic resonance in medicine.

[3]  Neil Woodhouse,et al.  An image acquisition and registration strategy for the fusion of hyperpolarized helium-3 MRI and x-ray CT images of the lung , 2008, Physics in medicine and biology.

[4]  Klaas P Pruessmann,et al.  Asymmetric quadrature split birdcage coil for hyperpolarized 3He lung MRI at 1.5T , 2008, Magnetic resonance in medicine.

[5]  H. Tiddens,et al.  Estimation of the radiation dose from CT in cystic fibrosis. , 2008, Chest.

[6]  Wiley Interscience,et al.  Chest physiotherapy during anesthesia for children with cystic fibrosis: Effects on respiratory function , 2007, Pediatric pulmonology.

[7]  H. Kauczor,et al.  Assessment of Morphological MRI for Pulmonary Changes in Cystic Fibrosis (CF) Patients: Comparison to Thin-Section CT and Chest X-ray , 2007, Investigative radiology.

[8]  D. Porteous,et al.  Lung clearance index is a sensitive, repeatable and practical measure of airways disease in adults with cystic fibrosis , 2007, Thorax.

[9]  H. Tiddens,et al.  Multiple-breath inert gas washout and spirometry versus structural lung disease in cystic fibrosis , 2007, Thorax.

[10]  Talissa A Altes,et al.  Magnetic resonance imaging of the lung in cystic fibrosis. , 2007, Proceedings of the American Thoracic Society.

[11]  Jim M. Wild,et al.  Assessment of lung disease in children with cystic fibrosis using hyperpolarized 3-Helium MRI: comparison with Shwachman score, Chrispin-Norman score and spirometry , 2007, European Radiology.

[12]  M. Stanton,et al.  Cystic fibrosis mortality and survival in the UK: 1947–2003 , 2007, European Respiratory Journal.

[13]  O. Hjalmarson,et al.  Immediate changes in blood-gas tensions during chest physiotherapy with positive expiratory pressure and oscillating positive expiratory pressure in patients with cystic fibrosis. , 2006, Respiratory care.

[14]  Jim M. Wild,et al.  Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: comparison with high resolution CT and spirometry , 2006, European Radiology.

[15]  J. Bradley,et al.  Evidence for physical therapies (airway clearance and physical training) in cystic fibrosis: an overview of five Cochrane systematic reviews. , 2006, Respiratory medicine.

[16]  D. Sin,et al.  Estimation of cancer mortality associated with repetitive computed tomography scanning. , 2006, American journal of respiratory and critical care medicine.

[17]  Eduard E de Lange,et al.  Hyperpolarized HHe 3 MRI of the lung in cystic fibrosis: assessment at baseline and after bronchodilator and airway clearance treatment. , 2005, Academic radiology.

[18]  Edwin J R van Beek,et al.  Quantitative analysis of regional airways obstruction using dynamic hyperpolarized 3He MRI—Preliminary results in children with cystic fibrosis , 2005, Journal of magnetic resonance imaging : JMRI.

[19]  Edwin J R van Beek,et al.  Combined helium‐3/proton magnetic resonance imaging measurement of ventilated lung volumes in smokers compared to never‐smokers , 2005, Journal of magnetic resonance imaging : JMRI.

[20]  Janet Stocks,et al.  Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis. , 2005, American journal of respiratory and critical care medicine.

[21]  J. Stocks,et al.  Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis , 2004, Thorax.

[22]  E. V. van Beek,et al.  Comparison between 2D and 3D gradient‐echo sequences for MRI of human lung ventilation with hyperpolarized 3He , 2004, Magnetic resonance in medicine.

[23]  P. Molina,et al.  High-resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests. , 2004, The Journal of pediatrics.

[24]  P. Jakob,et al.  Assessment of human pulmonary function using oxygen‐enhanced T1 imaging in patients with cystic fibrosis , 2004, Magnetic resonance in medicine.

[25]  R. Boucher,et al.  New concepts of the pathogenesis of cystic fibrosis lung disease , 2004, European Respiratory Journal.

[26]  P. Gustafsson,et al.  Evaluation of ventilation maldistribution as an early indicator of lung disease in children with cystic fibrosis , 2003, European Respiratory Journal.

[27]  D. Murphy Chest physiotherapy in cystic fibrosis: improved tolerance with nasal pressure support ventilation. , 2001, Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association.

[28]  R. Hubbard,et al.  International comparison of median age at death from cystic fibrosis. , 2000, Chest.

[29]  H C Charles,et al.  Cystic fibrosis: combined hyperpolarized 3He-enhanced and conventional proton MR imaging in the lung--preliminary observations. , 1999, Radiology.

[30]  D. Altman,et al.  Measuring agreement in method comparison studies , 1999, Statistical methods in medical research.

[31]  A. Harf,et al.  Chest physiotherapy in cystic fibrosis: improved tolerance with nasal pressure support ventilation. , 1999, Pediatrics.

[32]  A. Chrispin,et al.  The systematic evaluation of the chest radiograph in cystic fibrosis , 2005, Pediatric Radiology.

[33]  R. Busse,et al.  Cystic fibrosis: cost of illness and considerations for the economic evaluation of potential therapies. , 2003, PharmacoEconomics.