Descriptions of two new cases of Rocky Mountain spotted fever in Panama, and coincident infection with Rickettsia rickettsii in Rhipicephalus sanguineus s.l. in an urban locality of Panama City, Panama

Abstract The clinical and pathologic characterisation of two fatal cases of tick-borne rickettsiosis in rural (El Valle) and urban (City of Panama) Panama are described. Clinical and autopsy findings were non-specific, but the molecular analysis was used to identify Rickettsia rickettsii in both cases. No ticks were collected in El Valle, while in the urban case, R. rickettsii was detected in Rhipicephalus sanguineus s.l., representing the first molecular finding in this tick in Panama and Central America.

[1]  G. Álvarez-Hernández,et al.  Rocky Mountain spotted fever in Mexico: past, present, and future. , 2017, The Lancet. Infectious diseases.

[2]  D. Walker,et al.  Rickettsiae as Emerging Infectious Agents. , 2017, Clinics in laboratory medicine.

[3]  L. Killmaster,et al.  Vector competence of Amblyomma americanum (Acari: Ixodidae) for Rickettsia rickettsii. , 2017, Ticks and tick-borne diseases.

[4]  M. Labruna,et al.  Vectorial competence of Amblyomma tonelliae to transmit Rickettsia rickettsii , 2016, Medical and veterinary entomology.

[5]  S. V. Oliveira,et al.  A fatal case of Brazilian spotted fever in a non-endemic area in Brazil: the importance of having health professionals who understand the disease and its areas of transmission. , 2016, Revista da Sociedade Brasileira de Medicina Tropical.

[6]  E. Bermingham,et al.  Molecular Ecological Insights into Neotropical Bird–Tick Interactions , 2016, PloS one.

[7]  Roberto J. Miranda,et al.  Distribution of Spotted Fever Group Rickettsiae in Hard Ticks (Ixodida: Ixodidae) from Panamanian Urban and Rural Environments (2007–2013) , 2016, EcoHealth.

[8]  M. Labruna,et al.  Rickettsia rickettsii in Amblyomma patinoi Ticks, Colombia , 2015, Emerging infectious diseases.

[9]  G. Álvarez-Hernández,et al.  Clinical Profile and Predictors of Fatal Rocky Mountain Spotted Fever in Children from Sonora, Mexico , 2015, The Pediatric infectious disease journal.

[10]  Jorge Zavala-Castro,et al.  Guías Latinoamericanas de la RIICER para el diagnóstico de las rickettsiosis transmitidas por garrapatas , 2014 .

[11]  Oswaldo Gutiérrez Sotelo.  La práctica de la medicina en la Caja Costarricense de Seguro Social , 2013 .

[12]  S. Bermúdez,et al.  Serologic evidence of human Rickettsia infection found in three locations in Panamá. , 2012, Biomedica : revista del Instituto Nacional de Salud.

[13]  Angélica Castro,et al.  Nuevo caso de rickettsiosis humana en Panamá, a partir de evidencia serológica y clínica Informe de Caso , 2013 .

[14]  L. Hun,et al.  A fatal urban case of rocky mountain spotted fever presenting an eschar in San Jose, Costa Rica. , 2012, The American journal of tropical medicine and hygiene.

[15]  L. Hun,et al.  Case Report: A Fatal Urban Case of Rocky Mountain Spotted Fever Presenting an Eschar in San Jose´, Costa Rica , 2012 .

[16]  M. Tribaldos,et al.  Rocky Mountain spotted fever in Panama: a cluster description. , 2011, Journal of infection in developing countries.

[17]  S. Mattar,et al.  Rickettsioses in Latin America, Caribbean, Spain and Portugal , 2011 .

[18]  Roberto J. Miranda,et al.  Rickettsial infection in domestic mammals and their ectoparasites in El Valle de Antón, Coclé, Panamá. , 2011, Veterinary parasitology.

[19]  R. C.,et al.  Distribution of ectoparasites of Canis lupus familiaris L. (Carnivora: Canidae) from Panama , 2011 .

[20]  Roberto J. Miranda,et al.  Distribution of ectoparasites of Canis lupus familiaris L. (Carnivora: Canidae) from Panama , 2011 .

[21]  S. Buckingham,et al.  Managing Rocky Mountain spotted fever , 2009, Expert review of anti-infective therapy.

[22]  H. A. Thompson,et al.  Rocky Mountain Spotted Fever, Panama , 2007, Emerging infectious diseases.

[23]  D. Swerdlow,et al.  Rocky Mountain spotted fever from an unexpected tick vector in Arizona. , 2005, The New England journal of medicine.

[24]  D. Raoult,et al.  Differentiation of spotted fever group rickettsiae by sequencing and analysis of restriction fragment length polymorphism of PCR-amplified DNA of the gene encoding the protein rOmpA , 1996, Journal of clinical microbiology.

[25]  E. D. de RODANICHE.  Natural infection of the tick, Amblyomma cajennense, with Rickettsia rickettsii in Panama. , 1953, The American journal of tropical medicine and hygiene.

[26]  C. Calero,et al.  Rocky Mountain spotted fever in Panama; report of two cases. , 1952, The American journal of tropical medicine and hygiene.

[27]  E. D. de RODANICHE,et al.  Spotted fever in Panama; isolation of the etiologic agent from a fatal case. , 1950, The American journal of tropical medicine and hygiene.

[28]  G. Harrell.  ROCKY MOUNTAIN SPOTTED FEVER , 1949, Medicine.