Paediatric facial paralysis caused by Lyme borreliosis: a prospective and retrospective analysis.

The incidence of Lyme borreliosis (LB) was studied prospectively in 49 children (< 17 years of age) with 50 episodes of acute FP. In addition, 43 children with a history of FP (average follow-up of 5.2 y) were studied retrospectively for the outcome of FP and for the symptoms and signs of late LB. In the prospective study, 17 (34%) patients with FP proved to have acute LB. They all received antibiotic treatment and their FP had a favourable outcome. In the retrospective study the patients had had FP before the diagnostic tests for LB were available. Thus, none of the 43 patients had been diagnosed to have, or treated for, LB. The outcome of their FP had generally been favourable. None of them had any signs of late LB at the follow-up visit. Our results indicate that LB is a frequent cause of acute paediatric FP in an endemic area. In addition our data suggests that FP caused by LB in children has a favourable prognosis, even when left untreated.

[1]  R. Zbinden,et al.  Value of clinical symptoms, intrathecal specific antibody production and PCR in CSF in the diagnosis of childhood Lyme neuroborreliosis. , 1996, Klinische Padiatrie.

[2]  N. Hato,et al.  Bell Palsy and Herpes Simplex Virus: Identification of Viral DNA in Endoneurial Fluid and Muscle , 1996, Annals of Internal Medicine.

[3]  S. Galetta,et al.  Neurologic manifestations in children with Lyme disease. , 1995, Pediatrics.

[4]  D. Berggren,et al.  Borreliosis as a cause of peripheral facial palsy: a multi-center study. , 1995, ORL; journal for oto-rhino-laryngology and its related specialties.

[5]  R. Dattwyler,et al.  Neurologic manifestations in children with North American Lyme disease , 1993, Neurology.

[6]  D. Deluke,et al.  Melkersson-Rosenthal syndrome. Review of literature and case report. , 1992, International Journal of Oral & Maxillofacial Surgery.

[7]  R. Picken.  Polymerase chain reaction primers and probes derived from flagellin gene sequences for specific detection of the agents of Lyme disease and North American relapsing fever , 1992, Journal of clinical microbiology.

[8]  E. Peitersen.  Natural history of Bell's palsy. , 1992, Acta oto-laryngologica. Supplementum.

[9]  W. Krüger,et al.  Detection of Borrelia burgdorferi in cerebrospinal fluid by the polymerase chain reaction. , 1991, Journal of medical microbiology.

[10]  J. Ernerudh,et al.  Acute peripheral facial palsy: CSF findings and etiology , 1991, Acta neurologica Scandinavica.

[11]  P. Wahlberg.  Incidence of tick-bite in man in Aland Islands: reference to the spread of Lyme borreliosis. , 1990, Scandinavian journal of infectious diseases.

[12]  L. Thomander,et al.  Tick-borne Borrelia infection in patients with Bell's palsy. , 1987, Archives of otolaryngology--head & neck surgery.

[13]  H. Curtin,et al.  Facial Paralysis in Children: Differential Diagnosis , 1981, Otolaryngology Head & Neck Surgery.

[14]  Sonck Ce.  Erythema chronicum migrans in the face of three children , 1954 .