论文信息 - A rare case of granulomatosis with polyangiitis with involvement of the gastrointestinal system

A rare case of granulomatosis with polyangiitis with involvement of the gastrointestinal system

ABSTRACT We report a rare case of a 37-year-old man with granulomatosis with polyangiitis (GPA) with gastrointestinal system (GIS) involvement who needed 526 units of blood and blood product transfusions and was followed up in the intensive care unit (ICU). GIS involvement due to GPA is a rare condition that increases morbidity and mortality of patients. Patients may require ultramassive blood product transfusions. Thus, patients with GPA can be admitted to ICUs because of massive hemorrhage due to multisystem involvement, and survival is achievable with meticulous care through a multidisciplinary approach.

[1] Jonathan H. Esensten,et al. Outcomes after ultramassive transfusion in the modern era: An Eastern Association for the Surgery of Trauma multicenter study , 2021, The journal of trauma and acute care surgery.

[2] P. Cacoub,et al. Granulomatosis with polyangiitis (Wegener): clinical aspects and treatment. , 2014, Autoimmunity reviews.

[3] D. D'cruz,et al. Diagnosis and classification of granulomatosis with polyangiitis (aka Wegener's granulomatosis). , 2014, Journal of autoimmunity.

[4] E. Tezel,et al. Wegener’s granulomatosis with massive gastrointestinal hemorrhage due to jejunal and colonic involvement: Report of a case , 2008, Surgery Today.

[5] N. Fahmy,et al. Extensive gastrointestinal tract and thyroid involvement with Wegeners granulomatosis. , 2007, Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology.

[6] L. Guillevin,et al. Presentation and Outcome of Gastrointestinal Involvement in Systemic Necrotizing Vasculitides: Analysis of 62 Patients With Polyarteritis Nodosa, Microscopic Polyangiitis, Wegener Granulomatosis, Churg-Strauss Syndrome, or Rheumatoid Arthritis-Associated Vasculitis , 2005, Medicine.