RIP1 activates PI3K-Akt via a dual mechanism involving NF-kappaB-mediated inhibition of the mTOR-S6K-IRS1 negative feedback loop and down-regulation of PTEN.
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V. Rangnekar | E. Wong | M. Story | S. Burma | D. Boothman | M. Georgescu | K. Hatanpaa | D. Saha | B. Mickey | Dawen Zhao | A. Habib | Seongmi Park | Sandili S Chauncey