Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: from mechanism to therapy

[1]  Shanshan Hu,et al.  Catechol-Modified and MnO2-Nanozyme-Reinforced Hydrogel with Improved Antioxidant and Antibacterial Capacity for Periodontitis Treatment. , 2023, ACS biomaterials science & engineering.

[2]  Chen Zhang,et al.  Oral Delivery of Transformable Bilirubin Self‐Assembled System for Targeted Therapy of Colitis , 2023, Advanced healthcare materials.

[3]  Nagesh Kishan Panchal,et al.  Non-steroidal anti-inflammatory drugs (NSAIDs): A current insight into its molecular mechanism eliciting organ toxicities. , 2023, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[4]  Changren Zhou,et al.  ROS scavenging Manganese-loaded mesoporous silica nanozymes for catalytic anti-inflammatory therapy , 2023, Advanced Powder Technology.

[5]  Xu Cao,et al.  Linear ubiquitination of LKB1 activates AMPK pathway to inhibit NLRP3 inflammasome response and reduce chondrocyte pyroptosis in osteoarthritis , 2022, Journal of orthopaedic translation.

[6]  Li Wang,et al.  Multistage ROS-Responsive and Natural Polyphenol-Driven Prodrug Hydrogels for Diabetic Wound Healing. , 2022, ACS applied materials & interfaces.

[7]  G. Bifulco,et al.  Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: In Vitro and In Vivo Anti-Inflammatory Characterization , 2022, Journal of medicinal chemistry.

[8]  Lixue Liu,et al.  Functionalized Prussian Blue Nanozyme as Dual-Responsive Drug Therapeutic Nanoplatform Against Maxillofacial Infection via Macrophage Polarization , 2022, International journal of nanomedicine.

[9]  Yi Duan,et al.  Hydrogen gas alleviates lipopolysaccharide-induced acute lung injury and inflammatory response in mice , 2022, Journal of Inflammation.

[10]  Won Jong Kim,et al.  Biomimetic anti-inflammatory and osteogenic nanoparticles self-assembled with mineral ions and tannic acid for tissue engineering , 2022, Nano Convergence.

[11]  Chol-Jun Yu,et al.  Antioxidation activity of molecular hydrogen via protoheme catalysis in vivo: an insight from ab initio calculations , 2022, Journal of Molecular Modeling.

[12]  Guixue Wang,et al.  ROS responsive polydopamine nanoparticles to relieve oxidative stress and inflammation for ameliorating acute inflammatory bowel. , 2022, Biomaterials advances.

[13]  Salma Kouser,et al.  Synthesis, analgesic, anti-inflammatory, ulcerogenic evaluation, and docking study of (benzoylphenoxy)-N-{5-[2-methylphenyl-6-chlorobenzoxazole]} acetamides as COX/5-LOX inhibitor , 2022, Journal of Molecular Structure.

[14]  Yi Zhao,et al.  An ischemia-homing bioengineered nano-scavenger for specifically alleviating multiple pathogeneses in ischemic stroke , 2022, Journal of Nanobiotechnology.

[15]  Zhengbao Zha,et al.  Ultrathin Hafnium Disulfide Atomic Crystals with ROS-Scavenging and Colon-Targeting Capabilities for Inflammatory Bowel Disease Treatment. , 2022, ACS nano.

[16]  Xiang Gao,et al.  Carbon dots nanozyme for anti-inflammatory therapy via scavenging intracellular reactive oxygen species , 2022, Frontiers in Bioengineering and Biotechnology.

[17]  B. Zhu,et al.  Inhibition of H1N1 Influenza Virus-induced Apoptosis by Ebselen Through ROS-mediated ATM/ATR Signaling Pathways , 2022, Biological Trace Element Research.

[18]  Maowei Yang,et al.  Glycosaminoglycan-Based Hydrogel Delivery System Regulates the Wound Microenvironment to Rescue Chronic Wound Healing. , 2022, ACS applied materials & interfaces.

[19]  Rahim Ullah,et al.  Tannic acid inhibits lipopolysaccharide-induced cognitive impairment in adult mice by targeting multiple pathological features. , 2022, International immunopharmacology.

[20]  Bin Du,et al.  Folic acid-targeted pluronic F127 micelles improve oxidative stress and inhibit fibrosis for increasing AKI efficacy. , 2022, European journal of pharmacology.

[21]  Jinmin Zhao,et al.  NIR-driven polydopamine based nanoenzymes as ROS scavengers to suppress osteoarthritis progression , 2022, Materials Today Nano.

[22]  A. Shtil,et al.  The Thioredoxin System of Mammalian Cells and Its Modulators , 2022, Biomedicines.

[23]  Chun-xiao Hu,et al.  A narrative review of the protective effects of curcumin in treating ischemia-reperfusion injury , 2022, Annals of translational medicine.

[24]  Wei Jiang,et al.  Application of Metal-Based Nanozymes in Inflammatory Disease: A Review , 2022, Frontiers in Bioengineering and Biotechnology.

[25]  Shuai Chen,et al.  The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation , 2022, Neural regeneration research.

[26]  Yuanyi Zheng,et al.  Prussian Blue Scavenger Ameliorates Hepatic Ischemia-Reperfusion Injury by Inhibiting Inflammation and Reducing Oxidative Stress , 2022, Frontiers in Immunology.

[27]  D. Mecerreyes,et al.  Thioether-based ROS responsive polymers for biomedical applications. , 2022, Journal of materials chemistry. B.

[28]  Xu Chen,et al.  An Engineered, Self-Propelled Nanozyme as Reactive Oxygen Species Scavenger , 2022, Chemical Engineering Journal.

[29]  F. Guan,et al.  In situ forming and biocompatible hyaluronic acid hydrogel with reactive oxygen species-scavenging activity to improve traumatic brain injury repair by suppressing oxidative stress and neuroinflammation , 2022, Materials today. Bio.

[30]  Nanping Ai,et al.  Biliverdin/Bilirubin Redox Pair Protects Lens Epithelial Cells against Oxidative Stress in Age-Related Cataract by Regulating NF-κB/iNOS and Nrf2/HO-1 Pathways , 2022, Oxidative medicine and cellular longevity.

[31]  Xiankun Cao,et al.  Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation , 2022, Theranostics.

[32]  Zhenzhong Zhang,et al.  Physiologically Inspired Mucin Coated Escherichia coli Nissle 1917 Enhances Biotherapy by Regulating the Pathological Microenvironment to Improve Intestinal Colonization. , 2022, ACS nano.

[33]  B. Sullenger,et al.  Design of therapeutic biomaterials to control inflammation , 2022, Nature Reviews Materials.

[34]  H. M. Abdel-Mageed,et al.  Antioxidant-biocompatible and stable catalase-based gelatin–alginate hydrogel scaffold with thermal wound healing capability: immobilization and delivery approach , 2022, 3 Biotech.

[35]  Mingzhen Zhang,et al.  Biomimetic MOF Nanoparticles Delivery of C-Dot Nanozyme and CRISPR/Cas9 System for Site-Specific Treatment of Ulcerative Colitis. , 2022, ACS applied materials & interfaces.

[36]  L. Miao,et al.  Cerium oxide nanozyme attenuates periodontal bone destruction by inhibiting the ROS-NFκB pathway. , 2022, Nanoscale.

[37]  Jianjun Zhou,et al.  Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis , 2021, Frontiers in Physiology.

[38]  Jianliang Shen,et al.  Facile formation of injectable quaternized chitosan/tannic acid hydrogels with antibacterial and ROS scavenging capabilities for diabetic wound healing. , 2021, International journal of biological macromolecules.

[39]  Hongwei Gao,et al.  Fe-Curcumin Nanozyme-Mediated Reactive Oxygen Species Scavenging and Anti-Inflammation for Acute Lung Injury , 2021, ACS central science.

[40]  W. Xue,et al.  Self-polymerized Polydopamine-based Nanoparticles for Acute Kidney Injury Treatment through Inhibiting Oxidative Damages and Inflammatory. , 2021, The international journal of biochemistry & cell biology.

[41]  V. Ganapathy,et al.  Self-assembled nanoparticles with bilirubin/JPH203 alleviate imiquimod-induced psoriasis by reducing oxidative stress and suppressing Th17 expansion , 2021, Chemical Engineering Journal.

[42]  S. Seal,et al.  Cerium oxide nanoparticle conjugation to microRNA-146a mechanism of correction for impaired diabetic wound healing. , 2021, Nanomedicine : nanotechnology, biology, and medicine.

[43]  Kyu-Jae Lee,et al.  Antioxidant Properties of Hydrogen Gas Attenuates Oxidative Stress in Airway Epithelial Cells , 2021, Molecules.

[44]  P. Kang,et al.  Bilirubin Nanoparticles Protect Against Cardiac Ischemia/Reperfusion Injury in Mice , 2021, Journal of the American Heart Association.

[45]  Masafumi Takahashi,et al.  Loop Between NLRP3 Inflammasome and Reactive Oxygen Species. , 2021, Antioxidants & redox signaling.

[46]  A. Matsumoto,et al.  Molecular hydrogen suppresses Porphyromonas gingivalis lipopolysaccharide-induced increases in interleukin-1 alpha and interleukin-6 secretion in human gingival cells , 2021, Molecular and Cellular Biochemistry.

[47]  Hong Zhu,et al.  Nanoceria potently reduce superoxide fluxes from mitochondrial electron transport chain and plasma membrane NADPH oxidase in human macrophages , 2021, Molecular and Cellular Biochemistry.

[48]  H. Ta,et al.  Different approaches to synthesising cerium oxide nanoparticles and their corresponding physical characteristics, and ROS scavenging and anti-inflammatory capabilities. , 2021, Journal of materials chemistry. B.

[49]  Kai Chen,et al.  Curcumin-loaded sandwich-like nanofibrous membrane prepared by electrospinning technology as wound dressing for accelerate wound healing. , 2021, Materials science & engineering. C, Materials for biological applications.

[50]  Daidi Fan,et al.  Construction of multifunctional hydrogel based on the tannic acid-metal coating decorated MoS2 dual nanozyme for bacteria-infected wound healing , 2021, Bioactive materials.

[51]  Kyeongsoon Park,et al.  Multifunctional Tannic Acid-Alendronate Nanocomplexes with Antioxidant, Anti-Inflammatory, and Osteogenic Potency , 2021, Nanomaterials.

[52]  Craig J. Neal,et al.  Engineered nanoceria modulate neutrophil oxidative response to low doses of UV-B radiation through the inhibition of reactive oxygen species production. , 2021, Journal of biomedical materials research. Part A.

[53]  C. Keck,et al.  Hesperetin Nanocrystals Improve Mitochondrial Function in a Cell Model of Early Alzheimer Disease , 2021, Antioxidants.

[54]  S. Jon,et al.  A bilirubin-derived nanomedicine attenuates the pathological cascade of pulmonary fibrosis , 2021, Biomaterials.

[55]  Xiaoxuan Liu,et al.  Reactive oxygen species-responsive nanoplatforms for nucleic acid-based gene therapy of cancer and inflammatory diseases , 2021, Biomedical materials.

[56]  Marisa P. Sárria,et al.  Novel concept of exosome-like liposomes for the treatment of Alzheimer's disease. , 2021, Journal of controlled release : official journal of the Controlled Release Society.

[57]  J. Deng,et al.  Reactive-oxygen-species-scavenging nanomaterials for resolving inflammation , 2021, Materials today. Bio.

[58]  William Ho,et al.  An intrinsically bioactive hydrogel with on-demand drug release behaviors for diabetic wound healing , 2021, Bioactive materials.

[59]  Zhiguo Yuan,et al.  Biocatalytic and Antioxidant Nanostructures for ROS Scavenging and Biotherapeutics , 2021, Advanced Functional Materials.

[60]  Fabio Mollica,et al.  Hydrogen Atom Transfer from HOO. to ortho‐Quinones Explains the Antioxidant Activity of Polydopamine , 2021, Angewandte Chemie.

[61]  Zhipeng Gu,et al.  Reduced polydopamine nanoparticles incorporated oxidized dextran/chitosan hybrid hydrogels with enhanced antioxidative and antibacterial properties for accelerated wound healing. , 2021, Carbohydrate polymers.

[62]  Bradford J. Smith,et al.  Cerium oxide nanoparticle delivery of microRNA-146a for local treatment of acute lung injury , 2021, Nanomedicine: Nanotechnology, Biology and Medicine.

[63]  Zhengwei Mao,et al.  Construction of heparin-based hydrogel incorporated with Cu5.4O ultrasmall nanozymes for wound healing and inflammation inhibition , 2021, Bioactive materials.

[64]  Yufeng Zheng,et al.  Tannic Acid/Sr2+-Coated Silk/Graphene Oxide-Based Meniscus Scaffold with Anti-Inflammatory and Anti-ROS Functions for Cartilage Protection and Delaying Osteoarthritis. , 2021, Acta biomaterialia.

[65]  Mitchell A. Kuss,et al.  Tannic acid-inspired, self-healing, and dual stimuli responsive dynamic hydrogel with potent antibacterial and anti-oxidative properties. , 2021, Journal of materials chemistry. B.

[66]  S. Hirano,et al.  Potential Therapeutic Applications of Hydrogen in Chronic Inflammatory Diseases: Possible Inhibiting Role on Mitochondrial Stress , 2021, International journal of molecular sciences.

[67]  H. Cheong,et al.  Malonic Acid Isolated from Pinus densiflora Inhibits UVB-Induced Oxidative Stress and Inflammation in HaCaT Keratinocytes , 2021, Polymers.

[68]  Rutong Yu,et al.  In Situ implantable, post-trauma microenvironment-responsive, ROS Depletion Hydrogels for the treatment of Traumatic brain injury. , 2021, Biomaterials.

[69]  Ping Yang,et al.  Intracellular ethanol‐mediated oxidation and apoptosis in HepG2/CYP2E1 cells impaired by two active peptides from seahorse (Hippocampus kuda bleeler) protein hydrolysates via the Nrf2/HO‐1 and akt pathways , 2021, Food science & nutrition.

[70]  Yuanyi Zheng,et al.  Excavating bioactivities of nanozyme to remodel microenvironment for protecting chondrocytes and delaying osteoarthritis , 2021, Bioactive materials.

[71]  H. Feng,et al.  Diphenyl Diselenide Protects Motor Neurons through Inhibition of Microglia-Mediated Inflammatory Injury in Amyotrophic Lateral Sclerosis. , 2021, Pharmacological research.

[72]  Chuanglong He,et al.  Cartilage-targeting peptide-modified dual-drug delivery nanoplatform with NIR laser response for osteoarthritis therapy , 2021, Bioactive materials.

[73]  Qionglin Liang,et al.  Multi-shell nanocomposites based multienzyme mimetics for efficient intracellular antioxidation , 2021, Nano Research.

[74]  C. Keck,et al.  Investigating hesperetin nanocrystals with tailor-made sizes for the prevention and treatment of Alzheimer’s disease , 2021, Drug delivery and translational research.

[75]  Hyeran Kim,et al.  Lysophosphatidylcholine Enhances Bactericidal Activity by Promoting Phagosome Maturation via the Activation of the NF-κB Pathway during Salmonella Infection in Mouse Macrophages , 2020, Molecules and cells.

[76]  L. Saso,et al.  An Overview of Nrf2 Signaling Pathway and Its Role in Inflammation , 2020, Molecules.

[77]  H. Yang,et al.  Antioxidant and anti-inflammatory activities of Prussian blue nanozyme promotes full-thickness skin wound healing. , 2020, Materials science & engineering. C, Materials for biological applications.

[78]  Craig J. Neal,et al.  Ceria Nanoparticles Decrease UVA-Induced Fibroblast Death Through Cell Redox Regulation Leading to Cell Survival, Migration and Proliferation , 2020, Frontiers in Bioengineering and Biotechnology.

[79]  L. Chu,et al.  Tannic acid attenuates hepatic oxidative stress, apoptosis and inflammation by activating the Keap1‑Nrf2/ARE signaling pathway in arsenic trioxide‑toxicated rats. , 2020, Oncology reports.

[80]  P. Zhu,et al.  Hydrogen: A Novel Option in Human Disease Treatment , 2020, Oxidative medicine and cellular longevity.

[81]  Shaohua Jiang,et al.  Polydopamine free radical scavengers. , 2020, Biomaterials science.

[82]  E. Sinibaldi,et al.  Polydopamine Nanoparticles as an Organic and Biodegradable Multitasking Tool for Neuroprotection and Remote Neuronal Stimulation , 2020, ACS applied materials & interfaces.

[83]  S. Jon,et al.  Bilirubin nanomedicine alleviates psoriatic skin inflammation by reducing oxidative stress and suppressing pathogenic signaling. , 2020, Journal of controlled release : official journal of the Controlled Release Society.

[84]  T. Haqqi,et al.  Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[85]  Zui-su Yang,et al.  Physicochemical Properties of Collagen from Acaudina Molpadioides and Its Protective Effects against H2O2-Induced Injury in RAW264.7 Cells , 2020, Marine drugs.

[86]  Zhipeng Gu,et al.  ROS Scavenging Biopolymers for Anti‐Inflammatory Diseases: Classification and Formulation , 2020, Advanced Materials Interfaces.

[87]  Xiaoyuan Chen,et al.  Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases , 2020, Nature Communications.

[88]  Shikun Chen,et al.  Corticosterone Inhibits LPS-Induced NLRP3 Inflammasome Priming in Macrophages by Suppressing Xanthine Oxidase , 2020, Mediators of inflammation.

[89]  E. Mijiritsky,et al.  Albumin-impregnated bone granules modulate the interactions between mesenchymal stem cells and monocytes under in vitro inflammatory conditions. , 2020, Materials science & engineering. C, Materials for biological applications.

[90]  Yubin Huang,et al.  Absorbable Thioether Grafted Hyaluronic Acid Nanofibrous Hydrogel for Synergistic Modulation of Inflammation Microenvironment to Accelerate Chronic Diabetic Wound Healing , 2020, Advanced healthcare materials.

[91]  Craig J. Neal,et al.  Antioxidative photochemoprotector effects of cerium oxide nanoparticles on UVB irradiated fibroblast cells. , 2020, Colloids and surfaces. B, Biointerfaces.

[92]  Ying-zheng Zhao,et al.  Protective effects and mechanisms of bilirubin nanomedicine against acute pancreatitis. , 2020, Journal of controlled release : official journal of the Controlled Release Society.

[93]  Xinbing Sui,et al.  The emerging role of ferroptosis in inflammation. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[94]  D. Hoskin,et al.  Instrumental role for reactive oxygen species in the inflammatory response. , 2020, Frontiers in bioscience.

[95]  Qiang Yang,et al.  Poly(N-Isopropyl-Acrylamide)/Poly(γ-Glutamic Acid) Thermo-Sensitive Hydrogels Loaded with Superoxide Dismutase for Wound Dressing Application , 2020, International journal of nanomedicine.

[96]  R. Terracciano,et al.  Role of p38-mitogen-activated protein kinase in COPD: pathobiological implications and therapeutic perspectives , 2020, Expert review of respiratory medicine.

[97]  Jeong-Su Kim,et al.  Vitamin D and Endothelial Function , 2020, Nutrients.

[98]  M. Lu,et al.  Photosynthesis-inspired H2 generation using a chlorophyll-loaded liposomal nanoplatform to detect and scavenge excess ROS , 2020, Nature Communications.

[99]  Chengjie Deng,et al.  The role of JAK/STAT signaling pathway and its inhibitors in diseases. , 2020, International immunopharmacology.

[100]  Zhong Li,et al.  Activation of STAT-3 signalling by RECK downregulation via ROS is involved in the 27-hydroxycholesterol-induced invasion in breast cancer cells , 2020, Free radical research.

[101]  Jianhua Yao,et al.  miRNA-103 promotes chondrocyte apoptosis by down-regulation of Sphingosine kinase-1 and ameliorates PI3K/AKT pathway in osteoarthritis , 2019, Bioscience reports.

[102]  Resham Bhattacharya,et al.  Hydrogen sulfide signaling in mitochondria and disease , 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[103]  J. Moon,et al.  Hyaluronic acid-bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome, and immune responses in colitis. , 2019, Nature Materials.

[104]  Yuan He,et al.  The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation , 2019, International journal of molecular sciences.

[105]  Shuai Jiang,et al.  Mitochondrial electron transport chain, ROS generation and uncoupling (Review) , 2019, International journal of molecular medicine.

[106]  Yu Chen,et al.  Reactive Oxygen Species (ROS)-Based Nanomedicine. , 2019, Chemical reviews.

[107]  Eunkyoung Kim,et al.  Role of polydopamine's redox-activity on its pro-oxidant, radical-scavenging, and antimicrobial activities. , 2019, Acta biomaterialia.

[108]  J. Su,et al.  Acinetobacter baumannii outer membrane protein 34 elicits NLRP3 inflammasome activation via mitochondria-derived reactive oxygen species in RAW264.7 macrophages. , 2019, Microbes and infection.

[109]  Richard d'Arcy,et al.  Reactive Oxygen Species‐Responsive Nanoparticles for the Treatment of Ischemic Stroke , 2019, Advanced Therapeutics.

[110]  M. Harmsen,et al.  Reactive oxygen species (ROS) in macrophage activation and function in diabetes. , 2019, Immunobiology.

[111]  G. Sethi,et al.  Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication , 2019, Front. Oncol..

[112]  Gang Chen,et al.  Antioxidant and xanthine oxidase inhibitory properties and LC-MS/MS identification of compoundsof ethanolic extract from Mulberry leaves. , 2018, Acta scientiarum polonorum. Technologia alimentaria.

[113]  Jinyoung Yoo,et al.  Protective effects of diphenyleneiodonium, an NADPH oxidase inhibitor, on lipopolysaccharide‐induced acute lung injury , 2018, Clinical and experimental pharmacology & physiology.

[114]  Nam Soo Kim,et al.  Collagen-based sponge hastens wound healing via decrease of inflammatory cytokines , 2018, 3 Biotech.

[115]  J. Babon,et al.  The molecular details of cytokine signaling via the JAK/STAT pathway , 2018, Protein science : a publication of the Protein Society.

[116]  Xiangmei Zhou,et al.  The role of mitochondria in NLRP3 inflammasome activation. , 2018, Molecular immunology.

[117]  Sung Eun Kim,et al.  Design of a 3D BMP-2-Delivering Tannylated PCL Scaffold and Its Anti-Oxidant, Anti-Inflammatory, and Osteogenic Effects In Vitro , 2018, International journal of molecular sciences.

[118]  E. Wine,et al.  Regulation of Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κβ) in Inflammatory Bowel Diseases , 2018, Front. Pediatr..

[119]  Ho Yeon Son,et al.  Tannin-Titanium Oxide Multilayer as a Photochemically Suppressed Ultraviolet Filter. , 2018, ACS applied materials & interfaces.

[120]  Xiurong Yang,et al.  Polydopamine Nanoparticles as Efficient Scavengers for Reactive Oxygen Species in Periodontal Disease. , 2018, ACS nano.

[121]  T. G. Back,et al.  Cyclic Seleninate Esters, Spirodioxyselenuranes and Related Compounds: New Classes of Biological Antioxidants That Emulate Glutathione Peroxidase. , 2018, Chemistry.

[122]  R. Branicky,et al.  Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling , 2018, The Journal of cell biology.

[123]  Yugang Wang,et al.  Ebselen suppresses inflammation induced by Helicobacter pylori lipopolysaccharide via the p38 mitogen-activated protein kinase signaling pathway. , 2018, Molecular medicine reports.

[124]  Zhuang Liu,et al.  Polydopamine nanoparticles for the treatment of acute inflammation-induced injury. , 2018, Nanoscale.

[125]  M. Chien,et al.  The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance , 2018, Journal of Experimental & Clinical Cancer Research.

[126]  Yuan Cheng,et al.  ROS scavenging Mn3O4 nanozymes for in vivo anti-inflammation , 2018, Chemical science.

[127]  Lin Sun,et al.  Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis , 2018, Redox biology.

[128]  Chunhua Yan,et al.  Chitosan-coated cerium oxide nanocubes accelerate cutaneous wound healing by curtailing persistent inflammation , 2018 .

[129]  J. Kobayashi,et al.  Potential relationship between the biological effects of low-dose irradiation and mitochondrial ROS production , 2018, Journal of radiation research.

[130]  T. Kanneganti,et al.  Recent advances in inflammasome biology. , 2018, Current opinion in immunology.

[131]  J. T. Njardarson,et al.  Analysis of US FDA-Approved Drugs Containing Sulfur Atoms , 2018, Topics in Current Chemistry.

[132]  Tianyi Liu,et al.  Antioxidants Maintain Cellular Redox Homeostasis by Elimination of Reactive Oxygen Species , 2017, Cellular Physiology and Biochemistry.

[133]  A. Meireles,et al.  Dimethyl Sulfoxide (DMSO) Decreases Cell Proliferation and TNF-α, IFN-γ, and IL-2 Cytokines Production in Cultures of Peripheral Blood Lymphocytes , 2017, Molecules.

[134]  Masayuki Yamamoto,et al.  An Overview of the Advantages of KEAP1-NRF2 System Activation During Inflammatory Disease Treatment. , 2017, Antioxidants & redox signaling.

[135]  N. Bottari,et al.  Toxoplasmosis treatment with diphenyl diselenide in infected mice modulates the activity of purinergic enzymes and reduces inflammation in spleen. , 2017, Experimental parasitology.

[136]  Haocai Chang,et al.  Induction of reactive oxygen species: an emerging approach for cancer therapy , 2017, Apoptosis.

[137]  T. Hyeon,et al.  Ceria-Zirconia Nanoparticles as an Enhanced Multi-Antioxidant for Sepsis Treatment. , 2017, Angewandte Chemie.

[138]  Hsin‐Lung Chen,et al.  In Situ Nanoreactor for Photosynthesizing H2 Gas To Mitigate Oxidative Stress in Tissue Inflammation. , 2017, Journal of the American Chemical Society.

[139]  K. Vårum,et al.  Butyrate-Loaded Chitosan/Hyaluronan Nanoparticles: A Suitable Tool for Sustained Inhibition of ROS Release by Activated Neutrophils. , 2017, Macromolecular bioscience.

[140]  D. N. Chadee,et al.  MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells , 2017, Oncogene.

[141]  Dong Eon Kim,et al.  Bilirubin nanoparticles ameliorate allergic lung inflammation in a mouse model of asthma. , 2017, Biomaterials.

[142]  Alexander W. Magsam,et al.  Core-Cross-Linked Nanoparticles Reduce Neuroinflammation and Improve Outcome in a Mouse Model of Traumatic Brain Injury. , 2017, ACS nano.

[143]  K. Linher-Melville,et al.  The complex roles of STAT3 and STAT5 in maintaining redox balance: Lessons from STAT-mediated xCT expression in cancer cells , 2017, Molecular and Cellular Endocrinology.

[144]  Shao-Cong Sun,et al.  NF-κB signaling in inflammation , 2017, Signal Transduction and Targeted Therapy.

[145]  K. Leong,et al.  Functional Recovery of Contused Spinal Cord in Rat with the Injection of Optimal‐Dosed Cerium Oxide Nanoparticles , 2017, Advanced science.

[146]  Dong Yun Lee,et al.  Bilirubin nanoparticle preconditioning protects against hepatic ischemia-reperfusion injury. , 2017, Biomaterials.

[147]  K. Griendling,et al.  Zinc regulates Nox1 expression through a NF‐&kgr;B and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells , 2017, Free radical biology & medicine.

[148]  Zhongze Gu,et al.  Bio-inspired self-healing structural color hydrogel , 2017, Proceedings of the National Academy of Sciences.

[149]  C. Duvall,et al.  Drug-Free ROS Sponge Polymeric Microspheres Reduce Tissue Damage from Ischemic and Mechanical Injury. , 2017, ACS biomaterials science & engineering.

[150]  D. Schwartz,et al.  JAK–STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects , 2017, Drugs.

[151]  Dan Li,et al.  Exposure to PM2.5 induces aberrant activation of NF-κB in human airway epithelial cells by downregulating miR-331 expression. , 2017, Environmental toxicology and pharmacology.

[152]  Z. Qin,et al.  Combined NADPH and the NOX inhibitor apocynin provides greater anti‐inflammatory and neuroprotective effects in a mouse model of stroke , 2017, Free radical biology & medicine.

[153]  A. Matsuzawa.  Thioredoxin and redox signaling: Roles of the thioredoxin system in control of cell fate. , 2017, Archives of biochemistry and biophysics.

[154]  B. Kuster,et al.  K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria. , 2016, Immunity.

[155]  R. Roskoski.  Janus kinase (JAK) inhibitors in the treatment of inflammatory and neoplastic diseases. , 2016, Pharmacological research.

[156]  Pierre P. D. Kondiah,et al.  A dual pH/Redox responsive copper-ligand nanoliposome bioactive complex for the treatment of chronic inflammation. , 2016, International journal of pharmaceutics.

[157]  Jinho Park,et al.  Bilirubin Nanoparticles as a Nanomedicine for Anti-inflammation Therapy. , 2016, Angewandte Chemie.

[158]  N. Sahiner,et al.  Inherently antioxidant and antimicrobial tannic acid release from poly(tannic acid) nanoparticles with controllable degradability. , 2016, Colloids and surfaces. B, Biointerfaces.

[159]  I. Samudio,et al.  DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis , 2016, PloS one.

[160]  J. Hong,et al.  Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches , 2016, Cells.

[161]  W. Kao,et al.  Loss of IκB kinase β promotes myofibroblast transformation and senescence through activation of the ROS-TGFβ autocrine loop , 2016, Protein & Cell.

[162]  Emma L. Smith,et al.  The Regulation of NF-κB Subunits by Phosphorylation , 2016, Cells.

[163]  Dandan Wu,et al.  ROS and ROS-Mediated Cellular Signaling , 2016, Oxidative medicine and cellular longevity.

[164]  D. Granger,et al.  Reperfusion injury and reactive oxygen species: The evolution of a concept☆ , 2015, Redox biology.

[165]  Y. Iwamoto,et al.  Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases. , 2015, Molecular medicine reports.

[166]  Yanhang Hong,et al.  A poly(γ-glutamic acid)-based hydrogel loaded with superoxide dismutase for wound healing , 2015 .

[167]  Ravikumar Arvapalli,et al.  Effect of cerium oxide nanoparticles on sepsis induced mortality and NF-κB signaling in cultured macrophages. , 2015, Nanomedicine.

[168]  D. Pal,et al.  Free radicals, natural antioxidants, and their reaction mechanisms , 2015 .

[169]  E. Choi,et al.  Compromised MAPK signaling in human diseases: an update , 2015, Archives of Toxicology.

[170]  S. Ohta.  Molecular hydrogen as a preventive and therapeutic medical gas: initiation, development and potential of hydrogen medicine. , 2014, Pharmacology & therapeutics.

[171]  M. Herrmann,et al.  Working with "H2S": facts and apparent artifacts. , 2014, Nitric oxide : biology and chemistry.

[172]  Zhenyuan Miao,et al.  Updated research and applications of small molecule inhibitors of Keap1-Nrf2 protein-protein interaction: a review. , 2014, Current medicinal chemistry.

[173]  R. Touyz,et al.  Acute ethanol intake induces mitogen-activated protein kinase activation, platelet-derived growth factor receptor phosphorylation, and oxidative stress in resistance arteries , 2014, Journal of Physiology and Biochemistry.

[174]  M. Abdelsaid,et al.  Deletion of thioredoxin‐interacting protein preserves retinal neuronal function by preventing inflammation and vascular injury , 2014, British journal of pharmacology.

[175]  Min Suk Shim,et al.  Nanoparticles with dual responses to oxidative stress and reduced ph for drug release and anti-inflammatory applications. , 2014, ACS nano.

[176]  M. Harper,et al.  Unearthing the secrets of mitochondrial ROS and glutathione in bioenergetics. , 2013, Trends in biochemical sciences.

[177]  R. Touyz,et al.  NADPH oxidases, reactive oxygen species, and the kidney: friend and foe. , 2013, Journal of the American Society of Nephrology : JASN.

[178]  J. Arthur,et al.  Mitogen-activated protein kinases in innate immunity , 2013, Nature Reviews Immunology.

[179]  A. Khabir,et al.  Biological therapy of strontium-substituted bioglass for soft tissue wound-healing: responses to oxidative stress in ovariectomised rats. , 2013, Annales pharmaceutiques francaises.

[180]  G. Núñez,et al.  K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter. , 2013, Immunity.

[181]  M. Kaplan,et al.  STAT signaling in inflammation , 2013, JAK-STAT.

[182]  R. Siegel,et al.  New tricks from an old dog: mitochondrial redox signaling in cellular inflammation. , 2012, Seminars in immunology.

[183]  R. Germain,et al.  The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP , 2012, Nature.

[184]  Chuen-Mao Yang,et al.  Role of NADPH oxidase/ROS in pro-inflammatory mediators-induced airway and pulmonary diseases. , 2012, Biochemical pharmacology.

[185]  Takafumi Suzuki,et al.  Validation of the multiple sensor mechanism of the Keap1-Nrf2 system. , 2012, Free radical biology & medicine.

[186]  A. Alfadda,et al.  Reactive Oxygen Species in Health and Disease , 2012, Journal of biomedicine & biotechnology.

[187]  C. Luchese,et al.  Protective Effect of Diphenyl Diselenide on Ischemia and Reperfusion-Induced Cerebral Injury: Involvement of Oxidative Stress and Pro-Inflammatory Cytokines , 2012, Neurochemical Research.

[188]  Jiujiu Yu,et al.  Critical role for calcium mobilization in activation of the NLRP3 inflammasome , 2012, Proceedings of the National Academy of Sciences.

[189]  Hong Zhu,et al.  Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence , 2012, Experimental biology and medicine.

[190]  D. S. St. Clair,et al.  Manganese superoxide dismutase, MnSOD and its mimics. , 2012, Biochimica et biophysica acta.

[191]  Nicole S. Bryce,et al.  p38 MAPK inhibitors attenuate pro-inflammatory cytokine production and the invasiveness of human U251 glioblastoma cells , 2012, Journal of Neuro-Oncology.

[192]  E. Jung,et al.  Anti‐inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation , 2012, Immunology and cell biology.

[193]  Moshe Arditi,et al.  Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis. , 2012, Immunity.

[194]  I. Ivanović‐Burmazović,et al.  Biochemical insight into physiological effects of H₂S: reaction with peroxynitrite and formation of a new nitric oxide donor, sulfinyl nitrite. , 2012, The Biochemical journal.

[195]  P. Xu,et al.  Enzyme-Nanoporous Gold Biocomposite: Excellent Biocatalyst with Improved Biocatalytic Performance and Stability , 2011, PloS one.

[196]  M. Hersberger,et al.  Nrf2 is essential for cholesterol crystal‐induced inflammasome activation and exacerbation of atherosclerosis , 2011, European journal of immunology.

[197]  Jae-Hong Kim,et al.  Bioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen species , 2011, Molecules and cells.

[198]  Daniel L. Kastner,et al.  Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS) , 2011, The Journal of experimental medicine.

[199]  Q. Luo,et al.  Artificial selenoenzymes: designed and redesigned. , 2011, Chemical Society reviews.

[200]  Sky W. Brubaker,et al.  Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome , 2011, Infection and Immunity.

[201]  S. Ryter,et al.  Autophagy proteins regulate innate immune response by inhibiting NALP3 inflammasome-mediated mitochondrial DNA release , 2010, Nature Immunology.

[202]  T. Kondo,et al.  Protective effects of platinum nanoparticles against UV‐light‐induced epidermal inflammation , 2010, Experimental dermatology.

[203]  Biswal,et al.  NADPH Oxidase-Dependent Reactive Oxygen Species Mediate Amplified TLR4 Signaling and Sepsis-Induced Mortality in Nrf2-Deficient Mice , 2010, The Journal of Immunology.

[204]  Hye-Youn Cho,et al.  Nrf2 protects against airway disorders. , 2010, Toxicology and applied pharmacology.

[205]  J. Tschopp,et al.  Thioredoxin-interacting protein links oxidative stress to inflammasome activation , 2010, Nature Immunology.

[206]  Xianglin Shi,et al.  Reactive Oxygen Species-Activated Akt/ASK1/p38 Signaling Pathway in Nickel Compound-Induced Apoptosis in BEAS 2B Cells , 2010, Chemical research in toxicology.

[207]  D. Armstrong,et al.  Protein phosphatase 5 protects neurons against amyloid‐β toxicity , 2009, Journal of neurochemistry.

[208]  J. Blenis,et al.  Molecular mechanisms of mTOR-mediated translational control , 2009, Nature Reviews Molecular Cell Biology.

[209]  E. Sen,et al.  Ebselen abrogates TNFα induced pro‐inflammatory response in glioblastoma , 2009, Molecular oncology.

[210]  K. Rock,et al.  Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization , 2008, Nature Immunology.

[211]  R. Medzhitov.  Origin and physiological roles of inflammation , 2008, Nature.

[212]  Yoshihiro Kakeji,et al.  Deregulation of the Akt pathway in human cancer. , 2008, Current cancer drug targets.

[213]  M. Toledano,et al.  ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis , 2007, Nature Reviews Molecular Cell Biology.

[214]  M. Traber,et al.  Vitamin E, antioxidant and nothing more. , 2007, Free radical biology & medicine.

[215]  Q. She,et al.  AKT and cancer--is it all mTOR? , 2006, Cancer cell.

[216]  H. Sumimoto,et al.  Phagocytosis-Coupled Activation of the Superoxide-Producing Phagocyte Oxidase, a Member of the NADPH Oxidase (Nox) Family , 2006, International journal of hematology.

[217]  M. Cynader,et al.  Biliverdin reductase, a major physiologic cytoprotectant, suppresses experimental autoimmune encephalomyelitis. , 2006, Free radical biology & medicine.

[218]  C. Hsieh,et al.  Thioredoxin‐ASK1 complex levels regulate ROS‐mediated p38 MAPK pathway activity in livers of aged and long‐lived Snell dwarf mice , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[219]  D. Guertin,et al.  Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex , 2005, Science.

[220]  Ken Itoh,et al.  Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome. , 2005, Archives of biochemistry and biophysics.

[221]  I. Choi,et al.  Blockade of airway hyperresponsiveness and inflammation in a murine model of asthma by a prodrug of cysteine, L‐2‐ oxothiazolidine‐4‐carboxylic acid , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[222]  Masayuki Yamamoto,et al.  Nrf2-Keap1 defines a physiologically important stress response mechanism. , 2004, Trends in molecular medicine.

[223]  E. Tremoli,et al.  Apocynin prevents cyclooxygenase 2 expression in human monocytes through NADPH oxidase and glutathione redox-dependent mechanisms. , 2004, Free radical biology & medicine.

[224]  H. Drexler,et al.  5-Lipoxygenase is involved in the angiotensin II-induced NAD(P)H-oxidase activation. , 2003, Biochemical and biophysical research communications.

[225]  Sujay K. Singh,et al.  Hydrogen Peroxide Activates NF-κB through Tyrosine Phosphorylation of IκBα and Serine Phosphorylation of p65 , 2003, Journal of Biological Chemistry.

[226]  E Yoshida,et al.  Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription , 2001, Genes to cells : devoted to molecular & cellular mechanisms.

[227]  David S. McClintock,et al.  Role of Oxidants in NF-κB Activation and TNF-α Gene Transcription Induced by Hypoxia and Endotoxin1 , 2000, The Journal of Immunology.

[228]  B. Cochran,et al.  Activation of the JAK-STAT pathway by reactive oxygen species. , 1998, American journal of physiology. Cell physiology.

[229]  Jie Wu,et al.  Participation of Reactive Oxygen Species in the Lysophosphatidic Acid-stimulated Mitogen-activated Protein Kinase Kinase Activation Pathway (*) , 1995, The Journal of Biological Chemistry.

[230]  P. Baeuerle,et al.  Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1. , 1991, The EMBO journal.

[231]  B. Ames,et al.  Bilirubin is an antioxidant of possible physiological importance. , 1987, Science.

[232]  OUP accepted manuscript , 2022, European Heart Journal.

[233]  A. Mehmood,et al.  Stevia residue extract alone and combination with allopurinol attenuate hyperuricemia in fructose-PO-induced hyperuricemic mice. , 2019, Journal of food biochemistry.

[234]  Hyeyoung Kim,et al.  Effect of thiol antioxidants on lipopolysaccharide-induced cyclooxygenase-2 expression in pulmonary epithelial cells. , 2018, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[235]  R. Hoover,et al.  NADPH oxidase-2 mediates zinc deficiency-induced oxidative stress and kidney damage. , 2017, American journal of physiology. Cell physiology.

[236]  Ming-feng Yang,et al.  Enhanced Therapeutic Potential of Nano-Curcumin Against Subarachnoid Hemorrhage-Induced Blood–Brain Barrier Disruption Through Inhibition of Inflammatory Response and Oxidative Stress , 2015, Molecular Neurobiology.

[237]  F. Ichinose,et al.  Hydrogen Sulfide and Neuroinflammation. , 2015, Handbook of experimental pharmacology.

[238]  Fatema Z. Chowdhury,et al.  STAT2: A shape-shifting anti-viral super STAT. , 2013, JAK-STAT.

[239]  Bao-en Wang,et al.  HMGB1 promotes the synthesis of pro-IL-1β and pro-IL-18 by activation of p38 MAPK and NF-κB through receptors for advanced glycation end-products in macrophages. , 2012, Asian Pacific journal of cancer prevention : APJCP.

[240]  J. Sahni,et al.  Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line. , 2012, Journal of Alzheimer's disease : JAD.

[241]  Hassane Oudadesse,et al.  Antioxidative/oxidative effects of strontium-doped bioactive glass as bone graft. In vivo assays in ovariectomised rats , 2012 .

[242]  K. Krause,et al.  The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. , 2007, Physiological reviews.

[243]  J. Engelhardt,et al.  Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase. , 2006, The Journal of biological chemistry.

[244]  A. Toker,et al.  Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling. , 2004, Molecular and cellular biology.

[245]  N. Chandel,et al.  Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin. , 2000, Journal of immunology.

[246]  S. Ameshima,et al.  [Glutathione peroxidase]. , 1995, Nihon rinsho. Japanese journal of clinical medicine.

[247]  Jürg Tschopp,et al.  Serveur Académique Lausannois SERVAL serval.unil.ch , 2022 .

[248]  B. Gao,et al.  Clinical Pharmacology: Advances and Applications Dovepress the Clinical Potential of Influencing Nrf2 Signaling in Degenerative and Immunological Disorders , 2022 .